Brain Cancer News and Research

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There are two main types of brain cancer. Primary brain cancer starts in the brain. Metastatic brain cancer starts somewhere else in the body and moves to the brain. Brain tumors can be benign, with no cancer cells, or malignant, with cancer cells that grow quickly. Also called glioma, meningioma.

European approval of Temodal (temozolomide) capsules for treatment of glioblastoma multiforme

Schering-Plough announced today that the European Commission has granted approval of Temodal (temozolomide) Capsules for first-line use for the treatment of patients with newly diagnosed glioblastoma multiforme (GBM), the most common and aggressive form of primary brain cancer.

10 Jun 2005

Study of glial cells in the roundworm C. elegans may provide insight into a variety of human brain diseases

The key to understanding our brains may lie within a one-millimeter long worm, new research from Rockefeller University indicates. Reporting in the June issue of Developmental Cell, Shai Shaham, Ph.D., and graduate student Elliot Perens use the roundworm, C. elegans, to investigate the mysterious glial cell, which makes up 90 percent of the human brain and, when it malfunctions, can contribute to diseases like Parkinson's disease and schizophrenia.

9 Jun 2005

FDA hearings on silicone breast implants

On April 11-13, the FDA's advisory panel on General and Plastic Surgery Devices will once again meet to review data on the safety of silicone breast implants. The panel will vote Tuesday on Inamed Corporation's application for approval, and on Wednesday on Mentor Corporation's application.

11 Apr 2005

Diffusion MRI gives early indication if brain cancer therapy is effective

A special type of MRI scan that measures the flow of water molecules through the brain can help doctors determine early in the course of brain cancer regimen if a patient's tumor will shrink, a new study shows.

28 Mar 2005

Approval for Temodar (temozolomide) capsules for newly diagnosed glioblastoma multiforme

Schering-Plough today reported that the U.S. Food and Drug Administration (FDA) has granted approval for Temodar (temozolomide) Capsules for use in combination with radiotherapy for the treatment of adult patients with newly diagnosed glioblastoma multiforme (GBM), a form of malignant brain cancer.

16 Mar 2005

New chemotherapy gives hope to brain tumour patients

A large international study conducted by the European Organisation for Research and Treatment of Cancer (EORTC) in collaboration with the National Cancer Institute of Canada (NCIC) Clinical Trials Group demonstrated that the addition of a novel chemotherapy agent, Temozolomide (brand name: Temodal®) to radiation therapy increases survival in patients suffering from glioblastoma, a very aggressive form of a brain tumour.

9 Mar 2005

Researchers turn fatal brain cancer into treatable disease for children

Some children with a rare brain tumor that is considered almost universally fatal can be saved if they receive radiation therapy followed by tandem (given one after the other) cycles of high-dose chemotherapy.

3 Mar 2005

Third of cancer patients in Europe make use of complementary and alternative medicine

More than a third of cancer patients in Europe make use of complementary and alternative medicine (CAM), according to one of the largest surveys undertaken of CAM in cancer.

3 Feb 2005

"Frank Must Die" boy to undergo revolutionary surgery

A 9-year-old boy with brain cancer, who gained international attention when his mother launched an online auction to pay for his biopsy, will undergo the surgery at no cost thanks to internationally renowned surgeon Hrayr Shahinian, M.D. of the Skull Base Institute.

31 Jan 2005

Stem cell gene linked to a portion of one of the most common childhood brain cancers

Scientists at Johns Hopkins have linked a stem-cell gene to a portion of one of the most common childhood brain cancers, opening the door to tailored therapies that block the gene's tumor-promoting ability.

10 Nov 2004

Protein called Mrp4 blocks the access of the anti-cancer drug topotecan into the brain

A protein called Mrp4 blocks the access of the anti-cancer drug topotecan into the brain by transporting this agent back into the bloodstream, thus reducing the ability of this agent to reach tumors.

11 Oct 2004

Researchers identify common mutation in T-cell acute lymphocytic leukemia

Researchers at Brigham and Women’s Hospital (BWH) and Dana-Farber Cancer Institute (DFCI) have made a breakthrough discovery, identifying a common mutation in T-cell acute lymphocytic leukemia (T-ALL), an important form of cancer in children and adolescents.

11 Oct 2004

Trial shows which brain cancer patients benefit from temozolomide

An international team of scientists and cancer specialists has identified which patients with the deadly form of brain tumours called glioblastomas are likely to live longer if they are treated with temozolomide, and which patients are likely to get only marginal, if any, benefit.

28 Sep 2004

Study on the long-term health effects associated with silicone breast implants

It is estimated that between 1.5 million and 2 million women in this country have had breast implants since they first appeared on the market in 1962.

23 Sep 2004

Certain cancers might one day be cured without the use of toxic chemotherapy and radiation

The eradication of brain tumors in mice following treatment with a novel drug suggests that certain cancers might one day be cured without the use of toxic chemotherapy and radiation.

20 Sep 2004

Researchers are making inroads to understanding what makes brain tumors so hard to treat

When he's not in the operating room performing surgery, Donald M. O'Rourke, M.D., Associate Professor of Neurosurgery at the University of Pennsylvania School of Medicine is fighting brain tumors from the research laboratory bench.

16 Sep 2004

Researchers have discovered a possible way to distinguish lethal from localized prostate cancers

If future studies show their test -- measuring the level of activity of a signaling pathway called Hedgehog -- can predict which prostate cancers will spread, the results could revolutionize decision making processes for prostate cancer patients, the researchers say.

13 Sep 2004

Exposure to natural and man-made substances in the environment accounts for at least two-thirds of all the cases of cancer in the U.S.

These environmental factors include lifestyle choices like cigarette smoking, excessive alcohol consumption, poor diet, lack of exercise and excessive sunlight exposure. Other factors include exposure to certain medical drugs, hormones, radiation, viruses, bacteria, and chemicals that may be present in the air, water, food and workplace.

18 Aug 2004

Stanford researchers identify leukemia stem cells

A handful of leukemia cells constantly replenish the supply of cancerous cells, according to new work by Stanford University School of Medicine researchers.

11 Aug 2004

New treatment strategy for brain cancer

Virginia Commonwealth University Massey Cancer Center researchers have found that combining ionizing radiation with a secreted protein that selectively inhibits tumor cell growth and survival can target cancer cells and leave healthy cells alone, perhaps presenting a new approach for treating the deadliest type of brain tumor.

9 Aug 2004