Budding Yeast News and Research

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Researchers develop experimental approaches, analysis tools to understand phenotypic expression

The Human Genome Project, along with numerous parallel efforts to solve the DNA sequences of hundreds of animal, plant, fungal, and microbe genomes in the last few decades, has produced enormous amounts of genetic data with which researchers are struggling to keep pace.

23 Jun 2010

NSF Faculty Early Career Development Award for Zhihao Zhuang

Zhihao Zhuang, assistant professor in the Department of Chemistry and Biochemistry at the University of Delaware, has won the National Science Foundation Faculty Early Career Development Award.

17 Apr 2010

Mapping of all fragile sites of yeast S.cerevisiae may lead to better understanding of cancer development

The research group of Dr. Fran-ois Robert, a researcher at the Institut de recherches cliniques de Montr-al (IRCM), in collaboration with the team of Dr. Daniel Durocher (Samuel Lunenfeld Research Institute and University of Toronto) accomplished a technical breakthrough: they mapped all the fragile sites of a living organism, the budding yeast Saccharomyces cerevisiae. The method used by the researchers can be applied to humans. This study has been published online today in the scientific journal Nature Structural and Molecular Biology.

10 Feb 2010

New technology sheds light on intracellular transport

Using new technology developed in his University of Oregon lab, chemist Andrew H. Marcus and his doctoral student Eric N. Senning have captured what they describe as well-orchestrated, actin-driven, mitochondrial movement within a single cell.

18 Dec 2009

Regulatory differences between mother and daughter cells shed new light on cell division

When mother and daughter cells are created each time a cell divides, they are not exactly alike. They have the same set of genes, but differ in the way they regulate them. New research now reveals that these regulatory differences between mother and daughter cells are directly linked to how they prepare for their next split.

20 Oct 2009

Biologists discover link between CGG repeats in DNA and neurological disorders

Researchers have long known that some repetitive DNA sequences can make human chromosomes "fragile," i.e. appearing constricted or even broken during cell divisions.

12 Jan 2009

Biologists identify genes that prevent changes in physical traits due to environmental changes

New York University biologists have identified genes that prevent physical traits from being affected by environmental changes.

4 Nov 2008

Scientists identify 25 genes that regulate lifespan

Scientists at the University of Washington and other institutions have identified 25 genes regulating lifespan in two organisms separated by about 1.5 billion years in evolutionary change.

13 Mar 2008

Device allows scientists to control gene activity across generations of cells

Just as cells inherit genes, they also inherit a set of instructions that tell genes when to become active, in which tissues and to what extent.

4 Mar 2008

The cell size problem

For more than 100 years, scientists have tried to figure out the cell size problem: How does a cell know when it is big enough to divide?

25 Sep 2007

Researchers pinpoint when a cell is ready to reproduce

For more than 100 years, scientists have tried to figure out the cell size problem: How does a cell know when it is big enough to divide, In research conducted in budding yeast ( Saccharomyces cerevisiae ), scientists at Rockefeller University have now identified the cellular event that marks the moment when a cell knows it is big enough to commit to cell division and spawn genetic replicas of itself.

24 Sep 2007

Important step towards a spatially and temporally quantifiable model of the cell

Cell membranes are like two-dimensional fluids whose molecules are distributed evenly through lateral diffusion.

26 Apr 2007

DNA polymerase zeta gives cells with damaged DNA a new lease on life

Fortunately, our cells contain many enzymes devoted strictly to detecting and repairing any damage caused by these insults. In fact, failure of these enzymes to make needed repairs to genes can lead to the accumulation of mutations and, eventually, cell death or possibly cancer.

6 Jan 2006

Replication timing assays may allow much earlier cancer detection

Scientists have discovered a DNA sequence that is involved in controlling the timing of DNA replication. Because alterations in DNA replication timing are associated with cancer, this discovery may lead to improved methods for cancer detection.

26 Sep 2004