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Study: Most stroke survivors can safely take two types of common antidepressants

Most stroke survivors were able to safely take two types of common antidepressants, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2024.

1 Feb 2024

Tirzepatide shows success in maintaining weight loss in obese adults

Study finds that the anti-obesity medication tirzepatide effectively maintains weight loss in obese adults, offering a promising approach to managing obesity and related health complications.

12 Dec 2023

Intracellular journey: The penetration of antidepressants into cells, organelles, and membranes

Researchers in neuropsychopharmacology challenge conventional wisdom about antidepressants' actions, revealing significant intracellular activity that influences their effectiveness. Utilizing advanced technologies, the study prompts a reevaluation of drug targeting and mechanisms, opening new avenues for treating depression.

12 Oct 2023

GLP-1 weight loss drugs linked to heightened GI risks, says new study

Study from JAMA reveals that users of GLP-1 agonists, recent drugs for weight management, show a heightened risk of gastrointestinal complications like intestinal obstruction, gastroparesis, and pancreatitis. Though these effects are rare, those considering these drugs for weight loss should weigh the benefits against potential risks, especially if not using them for diabetes.

5 Oct 2023

GLP-1 agonists linked to higher risk for gastrointestinal complications

They're being hailed as an effective way to lose weight, but diabetes drugs like Ozempic may come with a heightened risk of severe gastrointestinal problems.

5 Oct 2023

Antidepressants may help prevent bipolar depression relapse

Treatment with modern antidepressants may help prevent patients with bipolar disorder from relapsing into a depressive episode, according to an international clinical trial led by researchers at the University of British Columbia.

2 Aug 2023

Research reveals a potential gap in recommended care for people with obesity and overweight

By being undiagnosed or untreated, a significant fraction of people with obesity or overweight are not getting the recommended care, despite an increase in new treatment options, according to research being presented on June 17 at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

18 Jun 2023

Intermittent fasting shows potential benefits for obesity treatment and brain-gut-microbiome health

A recent Nutrients journal study by researchers at the David Geffen School of Medicine at the University of California, Los Angeles, has discussed the effects of time-restricted eating on BGM and reviewed its promising effects in obesity treatment.

26 Mar 2023

Smoking cessation drug may help people stop using cocaine while in treatment for OUD

For some people receiving methadone for treatment of opioid use disorder (OUD), the co-use of opioids and stimulants such as cocaine is an issue.

15 Mar 2023

Augmenting an antidepressant with aripiprazole may help some older adults with treatment-resistant depression

For older adults with clinical depression that has not responded to standard treatments, adding the drug aripiprazole (brand name Abilify) to an antidepressant they're already taking is more effective than switching from one antidepressant to another, according to a new multicenter study led by Washington University School of Medicine in St. Louis.

3 Mar 2023

In the wake of Chantix's recall, Varenicline use for nicotine dependence dropped by 75%

The recent JAMA Network Open study evaluated how the Chantix recall influenced prescribing varenicline and other nicotine dependency medications. For this cross-sectional study, a large US-based national cohort was used. All relevant data between January 1, 2021, and June 30, 2022, was obtained from the national pharmacy benefit database.

7 Feb 2023

Commonly prescribed antidepressants can increase bacteria's resistance to antibiotics

University of Queensland researchers have found a range of commonly prescribed antidepressants can increase bacteria's resistance to antibiotic medications.

1 Feb 2023

AGA releases evidence-based guidelines that recommend new obesity medications and lifestyle changes

Diet and exercise fail for most adults who try to lose weight in the long-term. Today the American Gastroenterological Association (AGA) released new evidence-based guidelines strongly recommending that these patients with obesity use recently approved medications paired with lifestyle changes.

20 Oct 2022

The effectiveness of three repurposed drugs in preventing serious SARS-CoV-2 infection in non-hospitalized adults

Researchers conducted a phase III clinical trial to test the effectiveness of three repurposed drugs - metformin, ivermectin, and fluvoxamine, in preventing progression to severe COVID-19.

22 Aug 2022

Study shows efficacy and safety of cytisine as a smoking cessation therapy

Research published in the Journal of Thoracic Oncology shows cytisine may be a safe and effective smoking cessation therapy in lung cancer screening volunteers.

28 Jul 2022

Study assesses the effectiveness of e-cigarettes as a smoking cessation aid

Using e-cigarettes to stop smoking may result in fewer successful quit attempts than trying to quit using other smoking cessation aids, such as nicotine replacement therapy (NRT) or meds, suggests US research published online in the journal Tobacco Control.

8 Feb 2022

NRG Oncology CC004 trial: Bupropion does not improve sexual desire for female cancer survivors

Despite preliminary supporting evidence that the dopaminergic agent bupropion might improve sexual desire for female cancer survivors, the NRG Oncology CC004 clinical trial determined that bupropion did not improve outcomes when compared to a placebo.

10 Dec 2021

MRI brain imaging biomarkers bring new levels of precision for prescribing antidepressants

Research led by UT Southwestern has identified MRI brain imaging biomarkers that bring new levels of precision for prescribing the most effective antidepressants.

9 Nov 2021

Combination therapies are the most effective smoking cessation medicines, review finds

Combination therapies, particularly varenicline and nicotine replacement therapy (NRT) combined, are the most effective tobacco cessation pharmacotherapies, the largest review to examine the effectiveness and safety of electronic cigarettes (e-cigarettes) and medicines that people use to quit tobacco has found.

11 Oct 2021

WHO's new List of Essential Medicines prioritizes access to diabetes and cancer treatments

WHO today published the new edition of its Model Lists of Essential Medicines and Essential Medicines for Children, which include new treatments for various cancers, insulin analogues and new oral medicines for diabetes, new medicines to assist people who want to stop smoking, and new antimicrobials to treat serious bacterial and fungal infections.

1 Oct 2021