Calcification News and Research

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Study uses MRI to evaluate cardiovascular risk in WTC first responders

In the first study using magnetic resonance imaging (MRI) to evaluate cardiovascular risk in World Trade Center (WTC) first responders, researchers from Mount Sinai School of Medicine have found that the responders who experienced high levels of exposure to the initial dust cloud on September 11, 2001, demonstrate high-risk features of atherosclerosis.

17 Nov 2011

Genetic variant may increase severity of coronary artery disease in patients with diabetes

Researchers at Washington University School of Medicine in St. Louis have identified the first genetic variant associated with severity of coronary artery disease in patients with type 2 diabetes.

29 Sep 2011

High levels of calcium in coronary arteries increase risk of stroke, heart attack

The presence of calcium in coronary arteries is a much better predictor of heart attack and stroke than C-reactive protein among people with normal levels of LDL cholesterol, according to a study of more than 2,000 people led by a Johns Hopkins heart specialist.

19 Aug 2011

Vitamin D, UVB may help prevent dental caries

Large geographical variations in dental health and tooth loss among U.S. adolescents and young adults have been reported since the mid-1800s. The first study finding a north-south gradient in dental caries was a report of men rejected from the draft for the Civil War for lost teeth, from 8 per 1000 men in Kentucky to 25 in New England.

10 Aug 2011

Prosthetic heart valve market to reach $1.3 billion by 2017

The prosthetic heart valve market is expected to reach a value of $1.3 billion by 2017, according to a new report available from companiesandmarkets.com.

8 Aug 2011

Sorin Group's Mitroflow valve with PRT receives CE Mark approval

Sorin Group,, a global medical company and a leader in the treatment of cardiovascular diseases, announced today that it received the CE Mark approval for the Mitroflow Aortic Pericardial Heart Valve with PRT.

28 Jul 2011

Substances found in cigarette smoke damage blood vessels' endothelial cells

A research term headed by David Bernhard from the University Department of Surgery at the Medical University of Vienna has found out that substances found in cigarette smoke lead to blood vessels' endothelial cells constantly digesting themselves.

26 Jul 2011

Humans' desire to kill rats has only made them stronger

Over millennia, mice have thrived despite humanity's efforts to keep them at bay. A Rice University scientist argues some mice have found two ways to achieve a single goal -- resistance to common poison.

22 Jul 2011

ULMCA PCI with DES a viable option for low-risk patients with normal left ventricular function

23 Jun 2011

Positive results for unprotected left main coronary artery PCI with drug-eluting stents

Patients with normal left ventricular function who undergo elective unprotected left main coronary artery (ULMCA) percutaneous coronary intervention (PCI) with drug-eluting stents (DES) had favorable outcomes according to new research. Results of the multicenter, retrospective study are reported in the June issue of Catheterization and Cardiovascular Interventions, a journal published by Wiley-Blackwell on behalf of The Society for Cardiovascular Angiography and Interventions (SCAI).

22 Jun 2011

Positive results for unprotected left main coronary artery PCI with drug-eluting stents

22 Jun 2011

First genetic, biochemical tests for Idiopathic Infantile Hypercalcemia

A breakthrough in genetic research has uncovered the defect behind a rare hereditary children's disease that inhibits the body's ability to break down vitamin D. This discovery has led researchers to develop the first genetic and biochemical tests that positively identify the disease.

17 Jun 2011

Promising results from KAI-4169 program for CKD-MBD presented at ENDO 2011

KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced clinical and preclinical data from its lead program, KAI-4169, at the Endocrine Society's 93rd Annual Meeting (ENDO 2011) taking place in Boston, June 4-7, 2011. KAI-4169 is a novel pharmaceutical agent being developed for the treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD).

7 Jun 2011

Scleroderma is an independent determinant for coronary calcification, study suggests

A new study by researchers in Hong Kong suggests that systemic sclerosis is an independent determinant for moderate to severe coronary calcification or atherosclerosis.

11 May 2011

Research suggests systemic sclerosis is an independent risk factor for atherosclerosis

A new study by researchers in Hong Kong suggests that systemic sclerosis is an independent determinant for moderate to severe coronary calcification or atherosclerosis. Conventional cardiovascular risk factors such as age and hypertension predispose patients with systemic sclerosis to plaque build-up in the heart arteries similar to the general population. Details of this study are now available in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR).

10 May 2011

Specific inflammatory factor may be responsible for aortic stenosis development

Research from Karolinska Institutet in Sweden shows that a specific inflammatory factor may be important in the development of the heart valve disease aortic stenosis. The results suggest that anti-inflammatory medication could be a possible new treatment.

15 Mar 2011

KAI initiates enrollment in KAI-4169 Phase 2 study for secondary hyperparathyroidism

KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced enrollment of the first patients in a Phase 2 study of KAI-4169, a novel pharmaceutical agent being tested for the treatment of secondary hyperparathyroidism (SHPT), which is a frequent and serious complication of end-stage renal disease (ESRD).

14 Mar 2011

FDA approves ELANA Surgical Kit for standard bypass surgery in brain

U.S. Food and Drug Administration today approved a surgical kit that allows neurosurgeons to reroute blood flow around an aneurysm or a tumor in the brains of patients at greater risk of stroke during standard bypass surgery.

11 Mar 2011

Study: Low levels of Klotho protein may serve as early warning sign of CKD

Low levels of the anti-aging hormone Klotho may serve as an early warning sign of the presence of kidney disease and its deadly cardiovascular complications, according to findings by UT Southwestern Medical Center researchers.

18 Feb 2011

Rare new disease identified – calcium accumulates in blood vessels

A new rare disease has been identified. Louise Benge’s started having difficulty in walking when she was 25. She developed hardening and pain over her calves and hands. She worsened over the next 20 years. Her family physician in Mount Vernon, Ky., was at a loss, as were a vascular specialist, a hand specialist and a kidney specialist. Her two sisters and two brothers had the problem too, but no doctor could understand why.

3 Feb 2011

Calcification News and Research

Study uses MRI to evaluate cardiovascular risk in WTC first responders

Genetic variant may increase severity of coronary artery disease in patients with diabetes

High levels of calcium in coronary arteries increase risk of stroke, heart attack

Vitamin D, UVB may help prevent dental caries

Prosthetic heart valve market to reach $1.3 billion by 2017

Sorin Group's Mitroflow valve with PRT receives CE Mark approval

Substances found in cigarette smoke damage blood vessels' endothelial cells

Humans' desire to kill rats has only made them stronger

ULMCA PCI with DES a viable option for low-risk patients with normal left ventricular function

Positive results for unprotected left main coronary artery PCI with drug-eluting stents

Positive results for unprotected left main coronary artery PCI with drug-eluting stents

First genetic, biochemical tests for Idiopathic Infantile Hypercalcemia

Promising results from KAI-4169 program for CKD-MBD presented at ENDO 2011

Scleroderma is an independent determinant for coronary calcification, study suggests

Research suggests systemic sclerosis is an independent risk factor for atherosclerosis

Specific inflammatory factor may be responsible for aortic stenosis development

KAI initiates enrollment in KAI-4169 Phase 2 study for secondary hyperparathyroidism

FDA approves ELANA Surgical Kit for standard bypass surgery in brain

Study: Low levels of Klotho protein may serve as early warning sign of CKD

Rare new disease identified – calcium accumulates in blood vessels

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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