Capsid News and Research

RSS

A potential marker of increased histological activity in hepatitis C virus infection

Early, vigorous and sustained lymphocyte proliferative responses specific to hepatitis C virus (HCV) have been regarded as pivotal for viral clearance.

18 Feb 2009

Researchers identify clockwork that drives a powerful virus nanomotor

Peering at structures only atoms across, researchers have identified the clockwork that drives a powerful virus nanomotor.

30 Dec 2008

Advanced Cancer Therapeutics licenses technology to develop HPV vaccine

Advanced Cancer Therapeutics (ACT) has announced the signing of two new collaborative agreements that will advance development of the Company's novel human papillomavirus (HPV) vaccine program.

23 Jul 2008

Artificial viral shells for pinpoint drug delivery

Researchers at the Technion-Israel Institute of Technology and The Scripps Research Institute in California are designing an artificial viral shell as a valuable nano-container for pinpoint drug delivery, molecular computing components, and a host of other applications.

3 Jan 2008

Scientists learn three-dimensional structure of enzyme in unusual virus

Biologists have determined the three-dimensional structure of an unusual viral enzyme that is required in the assembly of new viruses.

18 Sep 2007

AACR's Sixth Annual Landon Awards recognize Richard Kolodner, Douglas Lowy and John Schiller

Scientists whose discoveries have led to fundamental advances in the science and treatment of cancer are the recipients of two prestigious international prizes offered by the Kirk A. and Dorothy P. Landon Foundation and the American Association for Cancer Research.

22 Mar 2007

How DNA is packed

The life cycles of many viruses include a self-assembly stage in which a powerful molecular motor must pack the DNA genome into the virus's preformed shell (the capsid). How it manages this intricate feat has been subject to debate, but we know that the DNA passes into the capsid shell through a channel formed by a structure called the connector. Scientists have speculated that rotation of the connector complex might feed the DNA into the capsid as it turns.

20 Feb 2007

Scientists discover how T-cell leukemia viruses evade defense mechanisms

National Cancer Institute (NCI) scientists have discovered how human T-cell leukemia virus type 1 (HTLV-1), which infects about 20 million people worldwide, evades being held in check by one of the body's natural defense mechanisms.

6 Feb 2007

Proteomic mass spectrometry helps identify viruses

Scientists have used mass spectrometry for decades to determine the chemical composition of samples but rarely has it been used to identify viruses, and never in complex environmental samples.

13 Apr 2006

Mass spectrometry could aid biodefense in rapidly detecting dangerous pathogens

Scientists have used mass spectrometry for decades to determine the chemical composition of samples but rarely has it been used to identify viruses, and never in complex environmental samples.

10 Apr 2006

New understanding of the critical molecular factors that permit viruses to jump from one species to another

Researchers studying strains of a lethal canine virus and a related human virus have determined why the canine virus was able to spread so quickly from cats to dogs, and then from sick dogs to healthy dogs.

19 Mar 2006

Researchers unmask secrets of a tiny virus that infects bacteria

Using powerful computer tools and cryo-electron microscopes, researchers at Baylor College of Medicine unmasked the secrets of a tiny virus that infects bacteria and, in doing so, opened the door to a better understanding of a variety of viruses that infect people and animals.

13 Feb 2006

Viruses can be forced to evolve in ways to benefit humans

Viruses and humans have evolved together over millions of years in a game of one-upmanship that, often as not, left humans sick or worse.

7 Feb 2006

Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer

Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer, thanks to a newly developed technique that enables scientists to mass-produce human papillomavirus (HPV) in the laboratory.

13 Jun 2005

Research accelerates the search for an effective cancer vaccine

By devising a novel way to package the genome of a common human tumor virus - the virus that causes common warts, genital warts and that is implicated in prevalent cancers - scientists have paved the way for making the pathogen far more accessible to biomedical science.

13 Jun 2005

WIN compound - a prototype drug for curing colds - is showing so much promise

An antiviral compound that wiggles its way into the common cold virus may provide one piece of the solution to halting the infection, say Purdue University scientists.

25 May 2005

Novel strategy to create a genetic vaccine against P. aeruginosa

Pseudomonas aeruginosa is a bacterium that can cause respiratory tract infections, which can be life threatening in patients who have cystic fibrosis. It is therefore important to develop a vaccine against this pathogen.

3 Apr 2005

DNA ejection from single phage particles

Studying phage, a primitive class of virus that infects bacteria by injecting its genomic DNA into host cells, researchers have gained insight into the driving force behind this poorly understood injection process, which has been proposed in the past to occur through the release of pressure accumulated within the viral particle itself.

7 Mar 2005

Virologists make major step towards understanding the process of HIV infection

A working group of virologists headed by Professor Hans-Georg Kräusslich at Heidelberg University Hospitals, jointly with Professor Hanswalter Zentgraf, Division of Applied Tumor Virology of the Deutsches Krebsforschungszentrum (German Cancer Research Center, DKFZ), have been the first to label Human Immunodeficiency Viruses (HIV) for visual investigations without inhibiting the functional characteristics of the virus.

28 Feb 2005