Catalyst News and Research

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Researchers create the first mouse model that develops a lymphoma the same way that humans do

This advancement has the potential to significantly speed the development of new, improved therapies for diffuse large B cell lymphoma (DLBCL), the most common type of human B cell lymphoma. Human B cell lymphomas cause 85 percent of non-Hodgkin's lymphomas, the sixth leading cause of cancer deaths in the United States.

17 May 2005

Simple and efficient method for creation of novel protein functions in an existing protein scaffold

By designing a molecular bridge, scientists at the University of Illinois at Urbana-Champaign have forged a successful pathway through a complex ocean of barriers: They've changed the function of a protein using a co-evolution approach.

8 May 2005

Molecular mechanism that desensitizes us to cold, discovered

Mount Sinai School of Medicine researchers have discovered how the membrane protein that allows us to sense cold works and how this protein becomes desensitized so that one no longer feels the cold.

27 Apr 2005

Isotopes for society

The nucleus of an atom contains protons and neutrons. However, some atoms of the same chemical element can have varying numbers of neutrons, giving so-called isotopes of that element.

27 Apr 2005

Researchers find ovarian cancer patients who appear to respond better than others to gefitinib, or Iressa

Researchers at Fox Chase Cancer Center in Philadelphia have identified a subset of ovarian cancer patients who appear to respond better than others to gefitinib, or Iressa. The research was presented today at the 96th Annual Meeting of the American Association for Cancer Research in Anaheim, Calif.

20 Apr 2005

New chemical reaction that could greatly accelerate pharmaceutical production

University of Toronto researchers have a developed a new chemical reaction that could greatly accelerate pharmaceutical production, while also cutting costs and toxic by-products.

19 Apr 2005

Hospital Compare gets thumbs up from National Quality Forum

The National Quality Forum (NQF) has applauded the public release of hospital performance measurement data through the launch of Hospital Compare.

3 Apr 2005

Scientists identify novel regulator of telomere homeostasis

Each of our 46 chromosomes is capped by a telomere – a long stretch of repeated DNA (TTAGG). Telomeres play a key protective function in our cells, and now Dr. In Kwon Chung and colleagues at Yonsei University (Seoul, Korea) and the University of Central Florida reveal a novel mechanism to modulate telomere length.

3 Apr 2005

Study links colic, maternal depression to family problems

Some families with new babies face excessive infant crying, or colic. And some new mothers go through maternal post-partum depression (PPD) following childbirth. Neither situation is considered healthy, but a recent study published in the Infant Mental Health Journal has found that the combined impact of colic and PPD can have a highly toxic outcome. Researchers have linked colicky babies and maternal depression to decrease in overall family functioning.

29 Mar 2005

MicroJet injector for painless injections

Parents know all too well the pain experienced by their children - and themselves - when the time comes for immunizations at the doctor's office.

21 Mar 2005

Massive weight loss patients continue to drive the growth in body contouring

More than 106,000 body contouring procedures were performed in 2004, up 77 percent over the last five years according to statistics released by the American Society of Plastic Surgeons.

21 Mar 2005

Massachusetts support of stem cell research

The Massachusetts Medical Society, the statewide association of physicians with some 18,000 members, has offered testimony before the Joint Committee on Economic Development and Emerging Technologies in support of Senate Bill 25, An Act Promoting Stem Cell Research.

17 Feb 2005

Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications

The Institute of Bioengineering and Nanotechnology (IBN) has developed a novel method to simultaneously control the size and morphology of nanoparticles, which can be used in pharmaceutical synthesis and novel biomedical applications.

8 Feb 2005

Novel approach to bioengineer artificial skin for burn victims

Each year more than 45,000 Americans suffer burns serious enough to require a hospital stay, according to the American Burn Association. While the traditional therapy of using skin grafts to cover burn sites has improved, a number of problems including scarring, infection and poor adhesion remain.

4 Jan 2005

Physicians remain negative in communicating a diagnosis of Down syndrome in newborn infants

A survey of mothers in the January issue of Pediatrics found that physicians remain overwhelmingly negative in communicating a diagnosis of Down syndrome in newborn infants.

3 Jan 2005

New malaria enzyme laid bare with help of computer calculations

Using only computers, a research team at Uppsala University in Sweden has managed to reveal both the structure and the function of a newly discovered enzyme from the most dangerous malaria parasite, Plasmodium falciparum.

8 Dec 2004

New technologies boost immunisation rates, safety

As global health leaders struggle to meet the United Nations goal of reducing mortality among the world's poorest children, vaccines are attracting more and more attention. The purchase of the vaccine is just the beginning, however, as the effectiveness of a vaccine is only as good as its delivery system.

6 Dec 2004