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Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

For twenty years, it has been understood that dystrophin is expressed in differentiated muscle fibers where it is part of a protein complex that crosses the membrane and connects the extracellular matrix to the actin network inside the cell to provide structural integrity. [More]
UTHealth researchers demonstrate new way to reduce preterm birth

UTHealth researchers demonstrate new way to reduce preterm birth

Using nanoparticles to engineer a special drug, a team of researchers from McGovern Medical School at The University of Texas Health Science Center at Houston has demonstrated in pre-clinical trials a new way to both reduce preterm birth and avoid the risks of medication in pregnancy to unborn babies. [More]
Lamin nucleoskeleton disordered in Alzheimer's

Lamin nucleoskeleton disordered in Alzheimer's

Brain cell death in Alzheimer's disease is linked to disruption of a skeleton that surrounds the nucleus of the cells, a researcher in the School of Medicine at The University of Texas Health Science Center at San Antonio said. [More]
New method could help scientists conduct in-depth research on malignant tumors in cancer patients

New method could help scientists conduct in-depth research on malignant tumors in cancer patients

Scientists at the Children's Medical Center Research Institute at UT Southwestern have pioneered a new method for conducting in-depth research on malignant tumors in patients, in the process discovering new complexities underlying cancer biology and overturning a nearly century-old perception about cancer metabolism. [More]
Novel non-invasive method of vagus nerve stimulation reduces depressive symptoms

Novel non-invasive method of vagus nerve stimulation reduces depressive symptoms

Researchers of a new study published in the current issue of Biological Psychiatry report successful reduction of depressive symptoms in patients using a novel non-invasive method of vagus nerve stimulation, or VNS. [More]
Duke scientists reveal how gut inflammation increases colon cancer risk

Duke scientists reveal how gut inflammation increases colon cancer risk

Chronic inflammation in the gut increases the risk of colon cancer by as much as 500 percent, and now Duke University researchers think they know why. [More]
Mitochondria essential for cellular ageing

Mitochondria essential for cellular ageing

An international team of scientists has for the first time shown that mitochondria, the batteries of the cells, are essential for ageing. [More]
NIH researchers identify genetic mutation responsible for vibratory urticaria

NIH researchers identify genetic mutation responsible for vibratory urticaria

Scientists at the National Institutes of Health have identified a genetic mutation responsible for a rare form of inherited hives induced by vibration, also known as vibratory urticaria. Running, hand clapping, towel drying or even taking a bumpy bus ride can cause temporary skin rashes in people with this rare disorder. [More]
Rockefeller University study shows how herpes virus causes traffic jam in immune system pathway

Rockefeller University study shows how herpes virus causes traffic jam in immune system pathway

With over half the U.S. population infected, most people are familiar with the pesky cold sore outbreaks caused by the herpes virus. The virus outsmarts the immune system by interfering with the process that normally allows immune cells to recognize and destroy foreign invaders. How exactly the herpes simplex 1 virus pulls off its nifty scheme has long been elusive to scientists. [More]
Duke researchers identify promising target for renal cell carcinomas

Duke researchers identify promising target for renal cell carcinomas

All cells need nutrients, but cancer cells are notoriously power hungry. As a result, cancer cells must alter their metabolism to provide the additional fuel needed for them to survive, grow and spread. [More]
UC Davis researchers develop Hepatitis virus-like particles to target breast cancer

UC Davis researchers develop Hepatitis virus-like particles to target breast cancer

UC Davis researchers have developed a way to use the empty shell of a Hepatitis E virus to carry vaccines or drugs into the body. The technique has been tested in rodents as a way to target breast cancer, and is available for commercial licensing through UC Davis Office of Research. [More]
Prevalence of past-year generalized anxiety disorder much higher among older adults with COPD

Prevalence of past-year generalized anxiety disorder much higher among older adults with COPD

The prevalence of past-year generalized anxiety disorder (GAD) for adults aged 50 and older with chronic obstructive pulmonary disease (COPD) is much higher compared to older adults without COPD (5.8% vs 1.7%), according to a new study published by University of Toronto researchers. [More]
New Leica Bioimaging Center for applied cell research opens in Munich

New Leica Bioimaging Center for applied cell research opens in Munich

Leica Microsystems and the Biomedical Center (BMC) of the Ludwig-Maximilians-Universität (LMU) Munich, Germany, will inaugurate the new core facility Bioimaging. Leica Microsystems will use the facility as reference and demo center. [More]
AstraZeneca’s TAGRISSO (osimertinib) approved in EU for metastatic EGFR T790M mutation-positive NSCLC

AstraZeneca’s TAGRISSO (osimertinib) approved in EU for metastatic EGFR T790M mutation-positive NSCLC

AstraZeneca today announced that the European Commission (EC) has granted conditional marketing authorisation for TAGRISSO™ (AZD9291, osimertinib) 80mg once-daily tablets for the treatment of adult patients with locally advanced or metastatic epidermal growth factor receptor (EGFR) T790M mutation-positive non-small cell lung cancer (NSCLC). [More]
Cell Therapy Catapult becomes Cell and Gene Therapy Catapult

Cell Therapy Catapult becomes Cell and Gene Therapy Catapult

The Cell Therapy Catapult, the UK organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the official change of its name to the Cell and Gene Therapy Catapult. [More]
New study highlights important milestone for future development of infant milk formula

New study highlights important milestone for future development of infant milk formula

New data published today in The Journal of Nutrition show that Bimuno, a unique galacto-oligosaccharide, is functionally similar to human milk oligosaccharides (HMOS) by producing comparable anti-inflammatory intestinal protection. [More]
New research identifies key enzyme linked to age-related increases in cancer and inflammation

New research identifies key enzyme linked to age-related increases in cancer and inflammation

For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration, according to new research from the Perelman School of Medicine at the University of Pennsylvania. [More]
Potential treatment target identified for fatty liver disease

Potential treatment target identified for fatty liver disease

Two proteins, p38 gamma and p38 delta, control the accumulation of fat in the liver, a process linked to the development of insulin resistance and diabetes, which are common outcomes of obesity. These findings are presented in an article published by researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC). [More]
Study reveals fetal origin for social and repetitive behavior deficits

Study reveals fetal origin for social and repetitive behavior deficits

Fetal development has been known to play an important role in social interaction, a fundamental behavior found in nearly all organisms, and later adult social behaviors. Autism, a highly heritable neurodevelopment disorder that causes difficulties with social interactions, has been postulated to be caused by neuron overgrowth in the prenatal period, although the precise timing and cause of this overgrowth has been unknown. [More]
'Housekeeping' gene may have a link to male infertility

'Housekeeping' gene may have a link to male infertility

Researchers at Iowa State University have found evidence that a "housekeeping" gene present in every cell of the body may have a link to male infertility. [More]
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