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Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Two recently discovered genetic differences between brain cancer cells and normal tissue cells -- an altered gene and a snippet of noncoding genetic material -- could offer clues to tumor behavior and potential new targets for therapy, Johns Hopkins scientists report. [More]
Sperm tail enzymes inspire nanobiotechnology

Sperm tail enzymes inspire nanobiotechnology

Just like workers in a factory, enzymes can create a final product more efficiently if they are stuck together in one place and pass the raw material from enzyme to enzyme, assembly line-style. [More]
New treatment prevents chemotherapy-induced hearing loss in children with cancer

New treatment prevents chemotherapy-induced hearing loss in children with cancer

Investigators from Children's Hospital Los Angeles and 37 other Children's Oncology Group hospitals in the U.S. and Canada have determined that sodium thiosulfate prevents cisplatin-induced hearing loss in children and adolescents with cancer. [More]
Combination of demineralized bone and gene therapy shows promise for treating pseudarthrosis

Combination of demineralized bone and gene therapy shows promise for treating pseudarthrosis

A team headed by Professor Albert Rizvanov, director of the Gene and Cell Technologies Open Lab, created a gene therapy drug that encodes growth factors for the stimulation of blood vessel and bone formation. [More]
WideCells signs LOI with Qigenix to undertake research at Manchester stem cell facility

WideCells signs LOI with Qigenix to undertake research at Manchester stem cell facility

WideCells Group PLC, the healthcare services company focused on providing stem cell banking services and ground breaking insurance for stem cell treatment, is pleased to announce that it has taken steps to secure a new revenue stream, in addition to the cash flow opportunities outlined in the Company’s prospectus published in July this year, having signed a Letter of Intent (‘LOI’) with Qigenix and its CEO, Dr. Todd Ovokaitys. [More]
Researchers receive Stafford Fox Medical Research Foundation grant to accelerate CFS diagnosis

Researchers receive Stafford Fox Medical Research Foundation grant to accelerate CFS diagnosis

Major improvement in the diagnosis of Chronic Fatigue Syndrome is expected following the award of $4m in funding to one of Australia’s foremost authorities on the condition. [More]
Elucigene collaborates with Congenica to develop new NGS kit for cystic fibrosis

Elucigene collaborates with Congenica to develop new NGS kit for cystic fibrosis

The emergence of new therapies that treat the causes of cystic fibrosis are creating an imperative for more accurate variant analysis. [More]
Researchers introduce first CVD method for producing degradable polymers

Researchers introduce first CVD method for producing degradable polymers

Polymerization by chemical vapor deposition (CVD) is a simple method for modifying surfaces by which topologically challenging substrates can be evenly coated with polymers. [More]
Applying quantitative microscopy to live cells

Applying quantitative microscopy to live cells

Microscopy's got a long history. It was developed about 350 years ago for scientists to visualize things they could discern, but not describe. The two pioneers of microscopy were Antoine van Leeuwenhoek, who developed the first microscope and soon after the renowned scientist, Robert Hooke. [More]
Menopausal women may experience accelerated decline in lung function, research shows

Menopausal women may experience accelerated decline in lung function, research shows

Menopausal women appear to experience an accelerated decline in lung function, according to new research published online ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. [More]
Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

Working with human immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular "off" switch for the inflammatory immune response that contributes to lung-constricting asthma attacks. [More]
New UGA research finds pathogen's motility activates immune response

New UGA research finds pathogen's motility activates immune response

Until now, a pathogen's ability to move through the body has been overlooked as a possible trigger of immune response, but new research from the University of Georgia College of Veterinary Medicine found that motility will indeed alarm the host and activate an immune response. [More]
UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs. [More]
Scientists discover unique genomic changes integral to testicular cancer development

Scientists discover unique genomic changes integral to testicular cancer development

Researchers led by scientists at Dana-Farber Cancer Institute say they have identified unique genomic changes that may be integral to testicular cancer development and explain why the great majority are highly curable with chemotherapy - unlike most solid tumors. [More]
Scientists discover molecular link between rare childhood genetic disease and major cancer gene

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

A team of researchers led by a University of Rhode Island scientist has discovered an important molecular link between a rare childhood genetic disease, Fanconi anemia, and a major cancer gene called PTEN. [More]
Monell Center receives Gates Foundation grant to support innovative global health research project

Monell Center receives Gates Foundation grant to support innovative global health research project

The Monell Center announced today that it has received a $345,000 grant from the Bill & Melinda Gates Foundation. The grant supports an innovative global health research project titled, "Developing Novel Pediatric Formulation Technologies for Global Health: Human Taste Assays." [More]
New three-dimensional map of cystic fibrosis protein offers new insights to treating fatal disease

New three-dimensional map of cystic fibrosis protein offers new insights to treating fatal disease

Rockefeller scientists have created the first three-dimensional map of the protein responsible for cystic fibrosis, an inherited disease for which there is no cure. [More]
Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells. [More]
Protective barrier inside chromosomes helps prevent errors during cell division, study finds

Protective barrier inside chromosomes helps prevent errors during cell division, study finds

Fresh insights into the structures that contain our genetic material could explain how the body's cells stay healthy. [More]
Study suggests new approach to treat white blood cells of sepsis patients

Study suggests new approach to treat white blood cells of sepsis patients

New research findings published in the Journal of Leukocyte Biology, suggest that treating the white blood cells of sepsis patients with antibodies that block programmed cell death-1 (PD-1) and programmed cell death ligand (PD-L1) molecules may restore their function and ultimately their ability to eradicate deadly bacteria. [More]
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