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Advanced Instruments launches novel GloCyte System at 68th AACC Annual Scientific Meeting

Advanced Instruments launches novel GloCyte System at 68th AACC Annual Scientific Meeting

Advanced Instruments, Inc., a leader in laboratory instrumentation, launches their GloCyte Automated Cell Counter System at the 68th AACC Annual Scientific Meeting & Clinical Lab Expo in Philadelphia, PA July 31-August 4. [More]
Study verifies human gene therapy in MPS I animal model

Study verifies human gene therapy in MPS I animal model

Researchers are closer to finding a better way to treat children with a rare metabolic disorder called MPS I. It is caused by a deficiency of the key enzyme IDUA needed to break down complex sugars in cells. [More]
Scientists develop photosensitive mimics of class of signaling molecules

Scientists develop photosensitive mimics of class of signaling molecules

Teams at Ludwig-Maximilians-Universitaet in Munich and EMBL have created photosensitive mimics of a class of signaling molecules, thus enabling their actions to be regulated by light, and affording new insights into the communications networks that control cellular metabolism. [More]
Study discovers mechanism by which bioscaffolds influence cellular behavior

Study discovers mechanism by which bioscaffolds influence cellular behavior

A study from the University of Pittsburgh School of Medicine and the McGowan Institute for Regenerative Medicine identifies a mechanism by which bioscaffolds used in regenerative medicine influence cellular behavior, a question that has remained unanswered since the technology was first developed several decades ago. [More]
New research sheds light on how fruit flies sense foods

New research sheds light on how fruit flies sense foods

Some people love avocados. Others hate them. For many of the latter, the fruit's texture is the source of their intense dislike. What gives? [More]
MIT researchers develop portable device to manufacture biopharmaceuticals on demand

MIT researchers develop portable device to manufacture biopharmaceuticals on demand

For medics on the battlefield and doctors in remote or developing parts of the world, getting rapid access to the drugs needed to treat patients can be challenging. [More]
Researchers identify reason why antidepressants take so long to work

Researchers identify reason why antidepressants take so long to work

An episode of major depression can be crippling, impairing the ability to sleep, work, or eat. In severe cases, the mood disorder can lead to suicide. But the drugs available to treat depression, which can affect one in six Americans in their lifetime, can take weeks or even months to start working. [More]
UAB researchers uncover vital mechanism for L-DOPA-induced-dyskinesia

UAB researchers uncover vital mechanism for L-DOPA-induced-dyskinesia

Though the drug levodopa can dramatically improve Parkinson's disease symptoms, within five years one-half of the patients using L-DOPA develop an irreversible condition -- involuntary repetitive, rapid and jerky movements. [More]
Study identifies two proteins crucial for self-renewal of skin stem cells

Study identifies two proteins crucial for self-renewal of skin stem cells

Our skin renews, heals wounds, and regenerates the hair that covers it thanks to a small group of stem cells. These cells continually produce new ones, which appear on the skin surface after a few days. [More]
T-cell technology could be used to treat ovarian tumors with no adverse effects

T-cell technology could be used to treat ovarian tumors with no adverse effects

With only incremental improvements in ovarian cancer survival over the last 40 years, there is a clear need for new treatment options with long-lasting results. Many researchers have turned toward the development of immunotherapies that direct T-cells to selectively eliminate ovarian tumor cells, but an appropriate therapeutic target for ovarian cancers has remained elusive. [More]
Novel conjugate therapy shows promise in destroying ALL cells with few side effects

Novel conjugate therapy shows promise in destroying ALL cells with few side effects

Researchers at UC Davis and Ionis Pharmaceuticals have developed a hybrid treatment that harnesses a monoclonal antibody to deliver antisense DNA to acute lymphoblastic leukemia (ALL) cells and that may lead to less toxic treatments for the disease. [More]
Research findings may offer new way to strengthen body’s natural defenses to battle pneumonia

Research findings may offer new way to strengthen body’s natural defenses to battle pneumonia

A molecule being targeted in cancer is also critical for the immune system's ability to battle pneumonia, researchers at the University of Virginia School of Medicine have determined. [More]
Scientists identify novel way to target lung cancer through KRAS gene

Scientists identify novel way to target lung cancer through KRAS gene

UT Southwestern Medical Center researchers have identified a new way to target lung cancer through the KRAS gene, one of the most commonly mutated genes in human cancer and one researchers have so far had difficulty targeting successfully. [More]
Researchers uncover novel virulence strategies employed by Leishmania parasite

Researchers uncover novel virulence strategies employed by Leishmania parasite

Professor Albert Descoteaux of INRS-Institut Armand-Frappier Research Centre and his team have discovered novel virulence strategies employed by the Leishmania parasite. [More]
CD4/CD8 ratio biomarker could help identify HIV-infected individuals at risk for heart disease

CD4/CD8 ratio biomarker could help identify HIV-infected individuals at risk for heart disease

The ratio of CD4 to CD8 T cells in the blood-a marker of immune system health and associated with mortality risk in the general population-is an independent predictor of coronary heart disease in HIV-infected patients, according to a new study published in AIDS Research and Human Retroviruses, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. [More]
Blood pressure hormone system important for cardiovascular health can promote obesity

Blood pressure hormone system important for cardiovascular health can promote obesity

New research by University of Iowa scientists helps explain how a hormone system often targeted to treat cardiovascular disease can also lower metabolism and promote obesity. [More]
Scientists identify new group of molecules that could slow tumour growth in prostate cancer patients

Scientists identify new group of molecules that could slow tumour growth in prostate cancer patients

Prostate cancer patients have been offered hope after scientists at Newcastle University, UK, have identified a new group of molecules that could be targeted to slow tumour growth. [More]
Human immune system proteins can help combat chlamydia infections

Human immune system proteins can help combat chlamydia infections

Scientists from Federal Research and Clinical Centre of Physical-Chemical Medicine, Koltzov Institute of Developmental Biology and MIPT have shown that peptidoglycan recognition proteins (PGLYRPs) of the human immune system can play a key role in the fight against chlamydia infections. Their study was published in Infection and Immunity. [More]
New gene therapy shows promising results for treating neurodegenerative disorders

New gene therapy shows promising results for treating neurodegenerative disorders

A new gene therapy approach designed to replace the enzyme that is deficient in patients with the inherited neurodegenerative disorders Tay-Sachs and Sandhoff diseases successfully delivered the therapeutic gene to the brains of treated mice, restored enzyme function, and extended survival by about 2.5-fold. [More]
Researchers discover genetic changes in MSH3 gene in patients with hereditary colon cancer

Researchers discover genetic changes in MSH3 gene in patients with hereditary colon cancer

The formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated. [More]
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