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AACR to honor Lewis C. Cantley with Princess Takamatsu Memorial Lectureship

AACR to honor Lewis C. Cantley with Princess Takamatsu Memorial Lectureship

The American Association for Cancer Research will honor Lewis C. Cantley, PhD, with the ninth annual Princess Takamatsu Memorial Lectureship at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22. [More]
Australian researchers find gene that drives aggressive form of triple-negative breast cancer

Australian researchers find gene that drives aggressive form of triple-negative breast cancer

Australian researchers have found that so-called 'triple-negative breast cancers' are two distinct diseases that likely originate from different cell types. This helps explain why survival prospects for women with the diagnosis tend to be either very good or very bad. [More]
UCSF professor wins Vilcek Prize in Biomedical Science

UCSF professor wins Vilcek Prize in Biomedical Science

Peter Walter was chosen as winner of the Vilcek Prize in Biomedical Science for his pioneering work on how proteins are transported between cellular compartments and for unraveling the components of a regulatory mechanism that cells use to handle stress tied to the aggregation of misshapen proteins. [More]
Stopping cellular quality-control mechanism can make chemotherapy more effective

Stopping cellular quality-control mechanism can make chemotherapy more effective

A University of Rochester team found a way to make chemotherapy more effective, by stopping a cellular quality-control mechanism, according to a study published today in Nature Communications. [More]
Radiation resistance in leukemia can be overcome by using new precision medicine, say researchers

Radiation resistance in leukemia can be overcome by using new precision medicine, say researchers

A team of researchers led by Fatih M. Uckun, MD, PhD, of The Saban Research Institute of Children's Hospital Los Angeles and Professor at the University of Southern California Keck School of Medicine has determined that radiation resistance in leukemia can be overcome by using an engineered protein they recently designed and developed as a new precision medicine against leukemia. [More]
Experts unveil strategic roadmap to advance treatments for people with lymphoma

Experts unveil strategic roadmap to advance treatments for people with lymphoma

A committee of lymphoma experts today unveiled a strategic roadmap identifying key priority areas in both infrastructure and research that will be critical for advancing treatments for people with lymphoma. [More]
3D respiratory tissue model shown to be effective for measuring impact of chemicals

3D respiratory tissue model shown to be effective for measuring impact of chemicals

A 3-dimensional model of human respiratory tissue has been shown to be an effective platform for measuring the impact of chemicals, like those found in cigarette smoke, or other aerosols on the lung. [More]
Taconic, Cellaria partner to facilitate use of patient-derived xenografts for oncology research

Taconic, Cellaria partner to facilitate use of patient-derived xenografts for oncology research

Taconic Biosciences and Cellaria Biosciences today announced that the two companies have entered into a scientific collaboration designed to facilitate and improve the utility of patient-derived xenografts (PDXs) in animal models for oncology and immuno-oncology research. Cellaria’s novel methodologies for generating cells from patient tumors will complement Taconic’s industry-leading portfolio of tissue humanized mouse models, which are well-suited as hosts for PDXs. [More]
apceth begins Agenmestencel-T Phase II clinical trial in gastrointestinal cancer patients

apceth begins Agenmestencel-T Phase II clinical trial in gastrointestinal cancer patients

apceth, a global leader in engineered cell therapies, today announced the successful completion of the Phase I and initiation of the Phase II part of its ongoing monocentric Phase I/II clinical trial TREAT-ME 1 with the engineered cell therapeutic product Agenmestencel-T, at the Klinikum Grosshadern in Munich. [More]
LifeCodexx announces promising results from proof-of-principle study of qPCR-based NIPT assay

LifeCodexx announces promising results from proof-of-principle study of qPCR-based NIPT assay

LifeCodexx AG today reports the successful outcome of a proof-of-principle of its novel assay for non-invasive prenatal testing (NIPT assay) based on quantitative real-time PCR (qPCR). This NIPT assay, designed to determine fetal aneuploidies from maternal blood, will offer significant advantages, such as enhanced test performance at affordable prices, over other prenatal examination methods. [More]
Updated guidelines for diagnosis, treatment of medullary thyroid carcinoma released

Updated guidelines for diagnosis, treatment of medullary thyroid carcinoma released

A Task Force convened by the American Thyroid Association released updated guidelines for the diagnosis and treatment of medullary thyroid carcinoma (MTC). The current document is the first revision of the original guidelines published in 2009. [More]
Philip Low to be recognized with AACR Award for Outstanding Achievement in Chemistry in Cancer Research

Philip Low to be recognized with AACR Award for Outstanding Achievement in Chemistry in Cancer Research

The American Association for Cancer Research will recognize Philip S. Low, PhD, with the ninth annual AACR Award for Outstanding Achievement in Chemistry in Cancer Research at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22. [More]
Helsinn, Mundipharma sign distribution and license agreement for anamorelin

Helsinn, Mundipharma sign distribution and license agreement for anamorelin

Helsinn, a Swiss Group focused on building quality cancer care, and Mundipharma, today announce that they have entered into a distribution and license agreement for the exclusive rights to anamorelin in China, Hong Kong and Macao. [More]
Aridis Pharmaceuticals begins Aerucin Phase 1 clinical study for treatment of acute pneumonia

Aridis Pharmaceuticals begins Aerucin Phase 1 clinical study for treatment of acute pneumonia

Aridis Pharmaceuticals, Inc., a biopharmaceutical company applying proprietary technologies to produce novel therapies for infectious diseases, announced today the initiation of a Phase 1 clinical study of Aerucin, the Company's fully human IgG1 monoclonal antibody (mAb) against Pseudomonas aeruginosa bacteria, which is being developed as an adjunctive treatment for acute pneumonia. [More]
Study shows high-fat diet may increase risk for depression, psychiatric disorders

Study shows high-fat diet may increase risk for depression, psychiatric disorders

Can the consumption of fatty foods change your behavior and your brain? High-fat diets have long been known to increase the risk for medical problems, including heart disease and stroke, but there is growing concern that diets high in fat might also increase the risk for depression and other psychiatric disorders. [More]
Brainstorm Cell Therapeutics provides business update, announces financial results for 2014

Brainstorm Cell Therapeutics provides business update, announces financial results for 2014

BrainStorm Cell Therapeutics Inc., a leading developer of adult stem cell technologies for neurodegenerative diseases, today announced financial results for the three months and year ended December 31, 2014. [More]
Metabolic imbalance can trigger respiratory diseases in early childhood

Metabolic imbalance can trigger respiratory diseases in early childhood

An imbalance in our metabolism can trigger inflammatory processes in the body and activate the immune system. In a recent study, published in the Journal of Allergy and Clinical Immunology, UFZ researchers have been able to show that this applies even to newborns and children under one year of age, and is correlated with the development of respiratory diseases in early childhood. [More]
Patients with sickle cell disease have sleep disordered breathing problem

Patients with sickle cell disease have sleep disordered breathing problem

A new study in the Journal of Clinical Sleep Medicine revealed that 44 percent of adults with sickle cell disease who report trouble sleeping actually have a clinical diagnosis of sleep disordered breathing, including sleep apnea, which lowers their oxygen levels at night. [More]
UVA researchers develop compound that could lead to improved leukemia treatments

UVA researchers develop compound that could lead to improved leukemia treatments

Researchers at the University of Virginia School of Medicine have developed a compound that delays leukemia in mice and effectively kills leukemia cells in human tissue samples, raising hopes that the drug could lead to improved treatments in people. The researchers call it an exciting "new paradigm" for treating leukemia. [More]
Immunotherapy reverses memory problems in animal model of Alzheimer's disease

Immunotherapy reverses memory problems in animal model of Alzheimer's disease

A new study from the University of Texas Medical Branch at Galveston has revealed that a single dose of an immunotherapy reverses memory problems in an animal model of Alzheimer's disease. The article appears in the March 25 issue of the Journal of Neuroscience. [More]
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