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Possible therapeutic approach to lowering LDL cholesterol and homocysteine levels

Canadian scientists report that mice genetically altered so as to lack either of the two different pathways through which humans, mice, and other animals provide lipids for high density and low density lipoproteins (HDL and LDL) did not appear to suffer any ill effects. But animals from both groups had markedly lower levels of cholesterol in their blood stream.

14 Jun 2004

People with extremely early or extremely late sleep times may suffer from Circadian Rhythm Sleep Disorder

You probably know "night owls," those people not ready to fall asleep until the wee hours of the morning. And, you may also know "larks," those early risers who wake before the sun comes up and are ready for bed right after dinner. People with extremely early or extremely late sleep times may suffer from Circadian Rhythm Sleep Disorder (CRSD).

11 Jun 2004

Bone marrow stem cells exposed to damaged liver tissue quickly convert into healthy liver cells

Bone marrow stem cells, when exposed to damaged liver tissue, can quickly convert into healthy liver cells and help repair the damaged organ, according to new research from the Johns Hopkins Kimmel Cancer Center.

2 Jun 2004

Research laboratory at the forefront of the science of metabolomics

A new $1.8 million research laboratory will catapult Iowa State University to the forefront of the science of metabolomics.

2 Jun 2004

₤16.5 million investment in stem cell research

A ₤16.5 million investment in stem cell research was announced today, 27th May, promising to speed the development of new treatments and cures from the laboratory to the clinic. In total, 57 multidisciplinary research grants have been awarded as part of the new monies allocated via the 2002 Government Spending Review to the UK Research Councils.

27 May 2004

International adult stem cell 'retraining' project starts in Birmingham

An exciting research project to utilise the body's own stem cells to regenerate areas of tissue damage is uniting scientists in Birmingham, London and Ontario, Canada. The University of Birmingham is leading a three year study with long term aims of helping stroke, Parkinsons and diabetes patients.

27 May 2004

Toxoplasma gondii discovery may help fight against malaria

University of North Carolina at Chapel Hill scientists have discovered a protein in the cell wall of parasites that’s crucial to the molecular mechanism allowing them to move between cells, survive and cause disease.

25 May 2004

Revolutionary self healing bandage that uses the patient's own cells

A revolutionary type of 'self healing' bandage that uses the patient's own cells is being developed. The technique has already been tried successfully on patients with diabetic ulcers and in the long-term could offer a more effective, quicker and cost efficient way of treating many types of slow-healing wounds such as pressure ulcers.

24 May 2004

Are we as crazy as mad cows?

When proteins in our body work properly, we can see, smell, consume and digest food, grow muscle and brain cells. But when these infinitely useful biological building blocks fail, the most pernicious diseases arise. Susan Lindquist has scrutinized the complex origami-like shapes of proteins and come to understand how structural mistakes can lead to a frightening class of neurodegenerative disorders, including “Mad Cow Disease.”

20 May 2004

Cell division can be halted in multiple ways, with implications for cancer

Brown University researchers have found that there are multiple independent ways to stop cell division, a phenomenon that prevents the spread of genetic mutation, which can make cells cancerous. Results of this research, along with an accompanying editorial, were published in the current issue of the journal Molecular Cell.

20 May 2004

Scientists may have figured out how to use stem cells to regenerate lost or injured tissue

In experiments with fruit flies, Johns Hopkins scientists have restored the insect's sperm-making stem cells by triggering cells on the way to becoming sperm to reverse course. The unexpected findings are described in the May 13 issue of Science.

19 May 2004

Closer to understanding the function of a protein linked to an inherited form of the movement disorder dystonia

The protein, torsinA, is defective in patients with DYT1 dystonia, an inherited condition that causes uncontrollable movements in the limbs and torso. Learning what torsinA does could be an important step toward developing a treatment for the disorder.

19 May 2004

Scientists move closer toward treatment for degenerative diseases

Scientists at McGill University's Faculty of Medicine have discovered a key step that will provide new targets for treatments of many degenerative diseases such as Alzheimer's, Cystic Fibrosis and Diabetes.

17 May 2004

Study suggests that the vitamins, such as E, C, and beta carotene, could raise bad form of cholesterol

The notion that antioxidant vitamins could provide a safe, convenient way to protect the heart from disease appears to have hit a pothole.

3 May 2004

New technique of identifying genes may help researchers developing drugs

A quick new technique able to identify genes that evolve rapidly as well as those that change slowly already has pinpointed new targets for researchers developing drugs against tuberculosis and malaria, and it could do the same for other infectious diseases, according to a paper in this week's Nature.

29 Apr 2004

A burst of brain energy depends more on a unique molecular cycle than on blood flow variation

A century old mystery is taking place in your head as you read these words. Blood vessels in regions of your brain are widening, bathing cells in an increased blood flow.

28 Apr 2004

Protein on the centrosome key to new strategies for stopping cancer growth

A Mayo Clinic discovery about a protein known as Dynamin-2 has thrown conventional wisdom for a loop. Finding the protein on the centrosome, a minute structure near a cell’s nucleus, may lead to new strategies for stopping cancer growth.

20 Apr 2004

Link between iron regulation and the immune system

Patients with chronic inflammatory disorders, including infections, inflammatory bowel disease, arthritis and cancer, commonly become anemic. The anemia can make them sicker, is sometimes severe enough to require a blood transfusion, and responds only partially to current treatments.

20 Apr 2004

Second-hand smoke scars and affects healing

Researchers at the University of California, Riverside have found that breathing “second-hand” smoke reduces the speed at which wounds heal, leading to greater levels of scarring.

17 Apr 2004

Secrets of the human body unveiled at new museum

Ned Kelly’s death mask, skeletons from the 1800s and more than 12,000 assorted anatomy and pathology specimens will be on display at a special media event to launch the opening of a unique new anatomy and pathology museum at the University of Melbourne.

16 Apr 2004