Cell Death News and Research

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Study reveals role of protein modification in neurodegenerative disease progression

Neurodegenerative diseases, such as Alzheimer's and Parkinson's, present a significant health challenge, affecting over 50 million people globally.

12 Feb 2024

Androgen receptor signaling found to upregulate gene driving melanoma severity in men

Method by which androgen-activated androgen receptors (ARs) increase fucosyltransferase 4 (FUT4) expression.

12 Feb 2024

New drug targets key mechanism in ALS, protects motor neurons

A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS).

8 Feb 2024

Smoking triggers red blood cell death, raising anemia and circulation concerns

Smoking significantly increases suicidal erythrocyte death, potentially leading to anemia and microcirculation issues, despite showing no adverse effects on overall red blood cell indices.

7 Feb 2024

New study sheds light on sex differences in allergic airway inflammation

Researchers explored how sex hormones and chromosomes influence allergic inflammation and gene expression in four-core genotype (FCG) mice exposed to house dust mites (HDMs).

7 Feb 2024

Eleven stroke researchers to be recognized during the 2024 International Stroke Conference

Eleven scientists leading the way in stroke research will be recognized during the American Stroke Association's International Stroke Conference 2024 for their exceptional professional achievements.

6 Feb 2024

Hydrogel with built-in antibiofilm and antioxidative functions promotes faster healing of infected chronic wounds

A novel hydrogel dressing was developed recently to combat both these undesirable characteristics and tested for its effects on diabetic-infected wound healing.

5 Feb 2024

Researchers discover mechanism that protects tissue after faulty gene expression

The genetic material, in the form of DNA, contains the information that is crucial for the correct functioning of every human and animal cell.

2 Feb 2024

Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.

1 Feb 2024

Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

New research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations has identified a next-generation BTK degrader that could help overcome treatment resistance in chronic lymphocytic leukemia (CLL) and related blood cancers.

1 Feb 2024

Gingko biloba compound injections linked to better stroke outcomes

People with ischemic (clot-caused) stroke had better early recovery of cognitive function if treated with intravenous injections of a combination of biologically active components of ginkgo biloba during the first two weeks after the stroke, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2024.

1 Feb 2024

Combination drug treatment could be effective against malignant peripheral nerve sheath tumors

A combination of two cancer drugs could be effective against malignant peripheral nerve sheath tumors (MPNSTs) -; soft tissue tumors that are stubbornly resistant to chemotherapy and radiation -; according to a laboratory study led by researchers at the Johns Hopkins Kimmel Cancer Center.

31 Jan 2024

mRNA therapy revives p53 to combat ovarian tumors

Ovarian cancer is often very aggressive and responds poorly to the therapies currently available. A recent study by Goethe University Frankfurt and University Hospital Frankfurt offers hope that this could change in the medium term.

24 Jan 2024

Nutrigenomics paves the way for customized diets in lactose intolerance care

The current evidence on omics tools that allow for developing tailored nutrition strategies for individuals with lactose intolerance (LI).

24 Jan 2024

New study reveals effective strategies against drug resistance in hospital-acquired pneumonia treatment

A novel rabbit infection model to investigate meropenem's resistance development.

23 Jan 2024

Lung cancer prediction using biomarkers based on bronchoalveolar fluid microbiomes

The lung microbiomes of patients with benign and malignant pulmonary diseases.

23 Jan 2024

Cancer drug holds promise for shrinking polycystic kidney cysts

Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function.

22 Jan 2024

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Researchers explored how Death Induced by Survival gene Elimination through the analysis of RNA-induced silencing complex-bound short RNAs in Alzheimer's disease models influences neuronal survival and correlates with neurotoxicity in AD.

22 Jan 2024

RecA protein skips "unwinding" step in DNA repair

Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a dangling single-strand end into intact double strands, and repairing the break based on the undamaged sequence.

20 Jan 2024

Immune checkpoint inhibitor target found to promote skin cancer growth

Programmed cell death 1 (PD-1) is an important target for immune checkpoint inhibitor therapies that block its signaling and boost T-cell activity. PD-1 inhibitors have been approved for treating various types of cancer.

19 Jan 2024

Cell Death News and Research

Study reveals role of protein modification in neurodegenerative disease progression

Androgen receptor signaling found to upregulate gene driving melanoma severity in men

New drug targets key mechanism in ALS, protects motor neurons

Smoking triggers red blood cell death, raising anemia and circulation concerns

New study sheds light on sex differences in allergic airway inflammation

Eleven stroke researchers to be recognized during the 2024 International Stroke Conference

Hydrogel with built-in antibiofilm and antioxidative functions promotes faster healing of infected chronic wounds

Researchers discover mechanism that protects tissue after faulty gene expression

Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

Gingko biloba compound injections linked to better stroke outcomes

Combination drug treatment could be effective against malignant peripheral nerve sheath tumors

mRNA therapy revives p53 to combat ovarian tumors

Nutrigenomics paves the way for customized diets in lactose intolerance care

New study reveals effective strategies against drug resistance in hospital-acquired pneumonia treatment

Lung cancer prediction using biomarkers based on bronchoalveolar fluid microbiomes

Cancer drug holds promise for shrinking polycystic kidney cysts

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

RecA protein skips "unwinding" step in DNA repair

Immune checkpoint inhibitor target found to promote skin cancer growth

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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