Cell Membrane News and Research

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New duo therapy offers hope for 'super blockage' of over-active immune system

A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.

15 Dec 2016

Elucigene collaborates with Congenica to develop new NGS kit for cystic fibrosis

The emergence of new therapies that treat the causes of cystic fibrosis are creating an imperative for more accurate variant analysis.

2 Dec 2016

New three-dimensional map of cystic fibrosis protein offers new insights to treating fatal disease

Rockefeller scientists have created the first three-dimensional map of the protein responsible for cystic fibrosis, an inherited disease for which there is no cure.

1 Dec 2016

Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

Researchers of the Sarcoma research group of the Bellvitge Biomedical Research Institute, led by Dr. Òscar Martínez-Tirado, have first described the methylation profile of Ewing's sarcoma, a cancer of bone and soft tissues that mainly affects children and teenagers.

1 Dec 2016

New research shows immune paralysis in sepsis patients can be reversed

Failure of the immune system during blood poisoning (sepsis) can be reversed by a specific sugar.

18 Nov 2016

New discovery may lead to targeted therapy for migraines

A PhD student at Xi'an Jiaotong-Liverpool University in Suzhou, China is carrying out work that could have a significant impact on drugs developed to prevent and treat migraines.

16 Nov 2016

TSRI study unravels how protein is directly responsible for sensing touch

A new study led by scientists at The Scripps Research Institute reveals that a protein first discovered at TSRI in 2010 is directly responsible for sensing touch.

14 Nov 2016

Researchers identify mechanism of how circadian clocks in neurons encode daily rhythms of excitability

Molecular clocks in cells throughout the body control many physiologic changes in a 24-hour day/night circadian rhythm -- among them the timing of sleep and wakefulness.

14 Nov 2016

Elucidating IDP behaviour on crowded membranes

IDPs are proteins that contain stretches of amino-acid sequence that are flexible and do not comprise stable structure in isolation. This is in contrast with a more traditional view of proteins as largely occupying a stable native structure that correlates with functions such as enzyme activity or binding.

10 Nov 2016

NCATS funds collaboration initiative aimed at repurposing antimalarial to combat Ebola virus

The National Center for Advancing Translational Sciences recently awarded $596,533.00 to Collaborations Pharmaceuticals, Inc. to initiate a partnership with Texas Biomedical Research Institute aimed at repurposing an antimalarial for use against the Ebola virus.

10 Nov 2016

New treatment with therapeutic short interfering RNA could help thwart cancer

In the fight against cancer, doctors dish out combination-blows of surgery, chemotherapy and other drugs to beat back a merciless foe. Now, scientists have taken early steps toward adding a stinging punch to clinicians' repertoire.

7 Nov 2016

Researchers identify heart defects in progeria patients that may raise risk of arrhythmias, premature death

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III, working in collaboration with colleagues at other centers in Spain and abroad, have identified defects in the hearts of progeria patients that appear to be related to an elevated risk of arrhythmias and premature death.

2 Nov 2016

Problems with nuclear membrane play role in leukemia, heart disease and aging disorders

We put things into a container to keep them organized and safe. In cells, the nucleus has a similar role: keeping DNA protected and intact within an enveloping membrane.

2 Nov 2016

Researchers identify possible trigger of chronic inflammation in people with diabetes

Inflammation is one of the main reasons why people with diabetes experience heart attacks, strokes, kidney problems and other, related complications. Now, in a surprise finding, researchers at Washington University School of Medicine in St. Louis have identified a possible trigger of chronic inflammation.

2 Nov 2016

Study reveals potential therapeutic targets for treating patients who carry IFNGR receptor mutation

The study began by taking the medical history of 11 children, all of whom had a disorder due to mycobacteria infections, as the basis. All were discovered to have the same phenotype with the same mutation, which was located in the interferon-gamma (IFNGR) receptor, so the group began to explore what was causing this dysfunction.

27 Oct 2016

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase.

20 Oct 2016

Novel device that uses gold nanowires may benefit biomedical professionals during medical procedures

Grown like a snowflake and sharpened with a sewing machine, a novel device by Kansas State University researchers may benefit biomedical professionals and the patients they serve during electrode and organ transplant procedures.

20 Oct 2016

DZNE scientists find new mechanism that allows damaged neurons to regenerate

Injuries to the spinal cord can cause paralysis and other permanent disabilities because severed nerve fibers do not regrow. Now, scientists of the German Center for Neurodegenerative Diseases have succeeded in releasing a molecular brake that prevents the regeneration of nerve connections.

7 Oct 2016

GDE2 protein could help predict course of neuroblastoma

The research group of Wouter Moolenaar of the Netherlands Cancer Institute (NKI) has, in collaboration with the group of Rogier Versteeg of the AMC Amsterdam, discovered a protein that can predict the course of neuroblastoma.

4 Oct 2016

Researchers uncover pneumonia causing bacteria as trigger for autoimmune disease GBS

Guillain-Barré syndrome (GBS) is an acute life-threatening disease of the nervous system that leads to sensory disturbances and acute flaccid paralysis.

3 Oct 2016

Cell Membrane News and Research

New duo therapy offers hope for 'super blockage' of over-active immune system

Elucigene collaborates with Congenica to develop new NGS kit for cystic fibrosis

New three-dimensional map of cystic fibrosis protein offers new insights to treating fatal disease

Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

New research shows immune paralysis in sepsis patients can be reversed

New discovery may lead to targeted therapy for migraines

TSRI study unravels how protein is directly responsible for sensing touch

Researchers identify mechanism of how circadian clocks in neurons encode daily rhythms of excitability

Elucidating IDP behaviour on crowded membranes

NCATS funds collaboration initiative aimed at repurposing antimalarial to combat Ebola virus

New treatment with therapeutic short interfering RNA could help thwart cancer

Researchers identify heart defects in progeria patients that may raise risk of arrhythmias, premature death

Problems with nuclear membrane play role in leukemia, heart disease and aging disorders

Researchers identify possible trigger of chronic inflammation in people with diabetes

Study reveals potential therapeutic targets for treating patients who carry IFNGR receptor mutation

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Novel device that uses gold nanowires may benefit biomedical professionals during medical procedures

DZNE scientists find new mechanism that allows damaged neurons to regenerate

GDE2 protein could help predict course of neuroblastoma

Researchers uncover pneumonia causing bacteria as trigger for autoimmune disease GBS

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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