Cell Metabolism News and Research

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Study may help find treatments for nerve cell damage, neurodegenerative disorders

Scientists from Kyoto University's Institute for Integrated Cell-Material Sciences in Japan have have discovered how nerve cells adjust to low energy environments during the brain's growth process.

13 Apr 2015

New study could point to potential ways to address defects in learning, memory

Just as some people seem built to run marathons and have an easier time going for miles without tiring, others are born with a knack for memorizing things, from times tables to trivia facts. These two skills—running and memorizing—are not so different as it turns out.

8 Apr 2015

Study identifies gut immune system as new, effective target for diabetes

A commonly-used drug to treat inflammatory bowel disease, such as Crohn's disease, has been shown to lower blood sugar levels in obese mice, potentially identifying the gut immune system as a new and effective target in treating diabetes in humans.

8 Apr 2015

Mitochondrial DNA movement: an interview with Professor Jiri Neuzil, Griffith University

According to our understanding, mitochondria undergo cycles of fusion-fission, i.e. they divide within the constraints of a cell and, upon cell division, each of the two daughter cells gets its ‘share’ of mitochondria.

29 Mar 2015

Key 'energy producing' protein plays a critical role in a good immune system

A good immune system relies on a key 'energy producing' protein in immune cells to develop immunity to vaccines and disease, an international team of scientists has found.

6 Mar 2015

Salt may help control infection

Researchers at Vanderbilt University and in Germany have found that sodium - salt - accumulates in the skin and tissue in humans and mice to help control infection.

4 Mar 2015

Researchers reveal new pathway for inhibiting growth of tumor cells tied to BRCA mutations

Inhibiting the action of a particular enzyme dramatically slows the growth of tumor cells tied to BRCA1 and BRCA2 genetic mutations which, in turn, are closely tied to breast and ovarian cancers, according to researchers at NYU Langone Medical Center.

3 Feb 2015

UH Case Medical Center researchers find that coenzyme A plays key role in cell metabolism

Case Western Reserve and University Hospitals Case Medical Center researchers and physicians have discovered that the molecule known as coenzyme A plays a key role in cell metabolism by regulating the actions of nitric oxide. Cell metabolism is the ongoing process of chemical transformations within the body's cells that sustains life, and alterations in metabolism are a common cause of human disease, including cancer and heart disease.

15 Jan 2015

Enzymes linked to diabetes, obesity play major roles in arthritis and leukemia

Enzymes linked to diabetes and obesity appear to play key roles in arthritis and leukemia, potentially opening up new avenues for treating these diverse diseases, according to new research at Washington University School of Medicine in St. Louis.

8 Jan 2015

Research may provide new route to prevention and treatment of diabetes

An analysis of the genomes and epigenomes of lean and obese mice and humans has turned up a wealth of clues about how genes and the environment conspire to trigger diabetes, Johns Hopkins researchers say.

6 Jan 2015

Cornerstone Pharmaceuticals initiates CPI-613 Phase I trial in patients with B-cell NHL

Cornerstone Pharmaceuticals, Inc., a clinical stage company and leader in the growing field of cancer metabolism-based therapeutics, today announced the initiation of a Phase I clinical trial assessing the safety and efficacy of escalating doses of CPI-613, in combination with bendamustine and rituximab, in patients with relapsed or refractory B-cell Non-Hodgkin lymphoma (NHL).

8 Dec 2014

New type of cancer therapy shows promise in patients with advanced leukemia

A new type of cancer therapy that targets an oncometabolite produced dramatic results in patients with advanced leukemia in an early-phase clinical trial. The study, led by Eytan M. Stein, MD, a medical oncologist at Memorial Sloan Kettering Cancer Center, was presented today at the 56th Annual Meeting of the American Society of Hematology.

8 Dec 2014

Researchers find way to prevent noise-induced hearing loss

Researchers from Weill Cornell Medical College and the Gladstone Institutes have found a way to prevent noise-induced hearing loss in a mouse using a simple chemical compound that is a precursor to vitamin B3. This discovery has important implications not only for preventing hearing loss, but also potentially for treating some aging-related conditions that are linked to the same protein.

3 Dec 2014

New research suggests that brain aging can be postponed if placed on a high-fat diet

New Danish-led research suggests that signs of brain aging can be postponed in mice if placed on a high-fat diet. In the long term, this opens the possibility of treatment of children suffering from premature aging and patients with Alzheimer's and Parkinson's disease. The research project is headed by the Center for Healthy Aging, University of Copenhagen and the National Institute of Health.

6 Nov 2014

Changes in cell metabolism slow growth of colorectal cancer

Cancer is an unwanted experiment in progress. As the disease advances, tumor cells accumulate mutations, eventually arriving at ones that give them the insidious power to grow uncontrollably and spread. Distinguishing drivers of cancer from benign mutations open opportunities for developing targeted cancer therapies.

30 Oct 2014

Cell Metabolism News and Research

Study may help find treatments for nerve cell damage, neurodegenerative disorders

New study could point to potential ways to address defects in learning, memory

Study identifies gut immune system as new, effective target for diabetes

Mitochondrial DNA movement: an interview with Professor Jiri Neuzil, Griffith University

Key 'energy producing' protein plays a critical role in a good immune system

Salt may help control infection

Researchers reveal new pathway for inhibiting growth of tumor cells tied to BRCA mutations

UH Case Medical Center researchers find that coenzyme A plays key role in cell metabolism

Enzymes linked to diabetes, obesity play major roles in arthritis and leukemia

Research may provide new route to prevention and treatment of diabetes

Cornerstone Pharmaceuticals initiates CPI-613 Phase I trial in patients with B-cell NHL

New type of cancer therapy shows promise in patients with advanced leukemia

Researchers find way to prevent noise-induced hearing loss

New research suggests that brain aging can be postponed if placed on a high-fat diet

Changes in cell metabolism slow growth of colorectal cancer

UAlberta researchers discover link between pulmonary hypertension, diabetes and cancer

Research shows FGF21 hormone acts directly on brain to regulate obesity

MicroRNA molecule plays crucial role in managing cell survival and growth

'Achilles heel' in metabolic pathway could stop growth of lung cancer cells

Research performed in anemic mice shows acetate stimulates the formation of red blood cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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