Cell Wall News and Research

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Bad news for disease-causing bacteria!

Scientists have what could be some very bad news for disease-causing bacteria. All three major classes of antibiotics that kill infectious bacteria do so in part by ramping up the production of harmful free radicals, researchers report in the September 7, 2007, issue of Cell, a publication of Cell Press.

10 Sep 2007

Nanotubes offer new approach to cancer radiotherapy

Radioactive elements, or radionuclides, are well-established anticancer agents whose main limitation is that they kill healthy cells almost as easily as they do tumors. But because nanoparticles can be targeted to tumors, researchers have seized on the idea of using nanoparticles to deliver radionuclides to tumors, thus sparing healthy tissues from radiation-induced damage.

22 Aug 2007

Antibacterial soaps show no health benefits over plain soaps

Antibacterial soaps show no health benefits over plain soaps and, in fact, may render some common antibiotics less effective, says a University of Michigan public health professor.

17 Aug 2007

Scientists find mechanisms controlling metastasis of breast cancer cells

When cancer cells dissociate from the original tumor and migrate via the blood stream to colonize distant organs, is the main cause of cancer death.

9 Aug 2007

White blood cells are picky about sugar

Biology textbooks are blunt - neutrophils are mindless killers. These white blood cells patrol the body and guard against infection by bacteria and fungi, identifying and destroying any invaders that cross their path. But new evidence, which may lead to better drugs to fight deadly pathogens, indicates that neutrophils might actually distinguish among their targets.

11 Jul 2007

Invertebrate immune systems are anything but simple

A hundred years since Russian microbiologist Elie Metschnikow first discovered the invertebrate immune system, scientists are only just beginning to understand its complexity.

23 Jun 2007

Discovery of new survival mechanism in common bacteria

Researchers at the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health, have discovered a survival mechanism in a common type of bacteria that can cause illness.

8 Jun 2007

Researchers track how spores break out of dormant state

Tapping into the unknown world of awakening dormant bacterial spores, researchers have revealed through atomic force microscopy (AFM) the alterations of spore coat and germ cell wall that accompany the transformation from a spore to a vegetative cell.

5 Jun 2007

Body uses a 'dual key' system to secure immune system

"Dual key" activation, in which two people must act in concert to launch a weapon, is often installed to safeguard highly destructive arms.

2 Apr 2007

Viral protein is an effective preventative against infection

For parents, eight million cases of acute middle-ear infections every year adds up to a lot of sleepless nights and trips to the pediatrician.

25 Mar 2007

Antibiotic doses could be reduced by up to 50 times using new approach

Steven Hagens, previously at the University of Vienna, told Chemistry & Industry, the magazine of the SCI, that certain bacteriophages, a type of virus that infects bacteria, can boost the effectiveness of antibiotics gentamicin, gramacidin or tetracycline.

29 Jan 2007

Sequella receives FDA fast track status for pulmonary tuberculosis drug

Sequella, Inc. has announced it has received Fast Track designation from the U.S. Food and Drug Administration (FDA) for SQ109, the company's proprietary lead drug candidate for treatment of pulmonary tuberculosis (TB).

22 Jan 2007

Researchers show brain injury may occur within one millisecond after head hits windshield

Research by a Sandia National Laboratories engineer and a University of New Mexico Health Sciences Center neurologist shows that brain injury may occur within one millisecond after a human head is thrust into a windshield as a result of a car accident.

7 Nov 2006

Transgenic goat's milk could help tackle children's intestinal disease

Milk produced by transgenic goats, which carry the gene for an antibacterial enzyme found in human breast milk, altered the intestinal bacteria in young goats and pigs that were fed the milk.

4 Aug 2006

Cell walls - an essential building block

Cancer cells, like houses, need building materials for their walls. And as with a house, the cell wall needs to be built at just the right moment to protect and allow the construction of internal components.

2 Aug 2006

Scientists discover a master key to microbes' pathogenic lifestyles

For some microbes, the transformation from a benign lifestyle in the soil to that of a potentially deadly human pathogen is just a breath away.

3 May 2006

Researchers find compound 10 times more effective than isoniazid, the leading anti-tuberculosis drug

Researchers at the Albert Einstein College of Medicine of Yeshiva University have synthesized chemicals that are up to 10 times more effective than isoniazid, the leading anti-tuberculosis drug.

28 Mar 2006

Crucial breakthrough in pectin biosynthesis

Most people know pectin as a common household gelling agent in making jams and jellies, but its uses are vast. It has anticancer properties, for instance, and may have a role in important biological functions including plant growth and development and defense against disease.

22 Mar 2006

Novel vaccine approach to listeria - potential protection against other intracellular bacterial pathogens

When bacterial pathogens attack the surface of a cell, vaccine-induced antibodies can mount a formidable defense and fend off the bad bugs.

21 Mar 2006

New molecule could help in treating hospital infections

The scientists replaced a single atom from the molecular structure of vancomycin aglycon, a glycopeptide antibiotic that attacks the bacteria by inhibiting cell wall synthesis, significantly increasing the drug's spectrum of activity.

24 Feb 2006