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Scientists discover genetic pathway responsible for brain development

Scientists discover genetic pathway responsible for brain development

Scientists at A*STAR's Institute of Medical Biology and Institute of Molecular and Cellular Biology have identified a genetic pathway that accounts for the extraordinary size of the human brain. [More]

Leica Microsystems offers preview of light sheet module for confocal microscope at ASCB annual meeting

At the annual meeting of the American Society for Cell Biology (ASCB) in Philadelphia, PA, USA, from December 6 to 10, 2014, Leica Microsystems offers visitors a preview of its latest development: a light sheet module as an optional add-on to the Leica TCS SP8 confocal microscope for the observation of developing organisms in real time and 3D. The synergy of light sheet and confocal microscopy opens novel fields of application. [More]
Phenotyping human diseases in mice: an interview with Professor Carola Vinuesa

Phenotyping human diseases in mice: an interview with Professor Carola Vinuesa

One of the main obstacles to finding effective therapies for human diseases has been our limited understanding of disease pathogenesis: we lack detailed knowledge of the cellular and molecular mechanisms that lead to the development of disease. [More]
Eminent molecular cell biologist awarded GRC fellowship

Eminent molecular cell biologist awarded GRC fellowship

The Gutenberg Research College of Johannes Gutenberg University Mainz has awarded the coveted GRC fellowship to Professor Krishnaraj Rajalingam. In the upcoming years, he will lead a research team at the Research Center for Immunotherapy at Mainz University. [More]
Automated biospecimen thawing: an interview with Dr Rolf Ehrhardt, CEO of BioCision

Automated biospecimen thawing: an interview with Dr Rolf Ehrhardt, CEO of BioCision

Surprisingly, even with decades of cryopreservation research, little progress has been made in the way frozen biospecimens are thawed. It’s still very common for researchers and clinicians to thaw cells and other frozen biological samples in a variety of manual ways ... [More]
Authors review current progress in developing transgenic pig models for human diseases

Authors review current progress in developing transgenic pig models for human diseases

Genetically engineered pigs, minipigs, and microminipigs are valuable tools for biomedical research, as their lifespan, anatomy, physiology, genetic make-up, and disease mechanisms are more similar to humans than the rodent models typically used in drug discovery research. [More]
Logos Biosystems enters agreement with Stanford University to License “Clarity™” Technology

Logos Biosystems enters agreement with Stanford University to License “Clarity™” Technology

Logos Biosystems, a leading developer of various cellular imaging instruments for life science research, announced that it has entered into an agreement with Stanford University in order to access to the intellectual properties for the Clarity™ technology. [More]

Microscope objectives for ultra-deep biological imaging introduced by Olympus

Two dedicated microscope objectives optimized for deep, high-resolution imaging of life science specimens up to 8mm beneath the surface have been introduced by Olympus. [More]
3D brain-like tissue: an interview with Professor David Kaplan, Tufts University

3D brain-like tissue: an interview with Professor David Kaplan, Tufts University

In 2D, neurons tend to form limited connectivity reflective of the 3D complexity in the brain and have more limited cultivation time before reduction in functions. [More]
Einstein-Montefiore researchers to present latest finding on aging research at GSA 2014

Einstein-Montefiore researchers to present latest finding on aging research at GSA 2014

Investigators at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center will present their latest aging research at the Gerontological Society of America's 67th Annual Scientific Meeting. [More]
Lucideon to run Biodensol together with the University of Lyon

Lucideon to run Biodensol together with the University of Lyon

Lucideon is pleased to announce that, together with the University of Lyon, it has been successful in its application to run ‘Biodensol’, a 7th framework European project to provide a network for initial training in the field of dentistry. [More]
Discovery may provide new therapeutic avenue to target autophagy in tumors

Discovery may provide new therapeutic avenue to target autophagy in tumors

No matter what type of chemotherapy you attack a tumor with, many cancer cells resort to the same survival tactic: They start eating themselves. [More]
Scanning electron microscope for 3D volume imaging of cells and tissues announced by FEI

Scanning electron microscope for 3D volume imaging of cells and tissues announced by FEI

FEI (NASDAQ: FEIC) announced today its new Teneo VS™ scanning electron microscope (SEM), which offers a VolumeScope™ capability for life science applications. The Teneo platform tightly integrates FEI’s latest-generation SEM with VolumeScope, an in-chamber microtome and proprietary analytical software to provide fully-automated, large-volume reconstructions with dramatically improved z-axis resolution. [More]
Protein p66ShcA shows promise as biomarker to identify breast cancers with poor prognoses

Protein p66ShcA shows promise as biomarker to identify breast cancers with poor prognoses

A protein named p66ShcA shows promise as a biomarker to identify breast cancers with poor prognoses, according to research published ahead of print in the journal Molecular and Cellular Biology. [More]
Allen Institute for Brain Science welcomes visiting scientist engineer

Allen Institute for Brain Science welcomes visiting scientist engineer

The Allen Institute for Brain Science welcomes a visiting scientist from Harvard and a visiting engineer from Georgia Tech: Sharad Ramanathan, Ph.D.; and Craig Forest, Ph.D. Both Ramanathan and Forest will bring their distinct knowledge and backgrounds to the expanding scientific teams at the Allen Institute. [More]
Live cell imaging solution launched by QImaging

Live cell imaging solution launched by QImaging

QImaging™ today launched a new, all-in-one camera package that supports demanding live cell fluorescence imaging requirements. The Live Cell Imaging Package provides researchers with the sensitivity of EMCCD and the versatility of sCMOS camera technologies by combining QImaging’s Rolera™ Thunder EMCCD and optiMOS™ sCMOScameras. Now, researchers can address their unique imaging needs for a broader, more diverse set of scientific applications. [More]
Study sheds light on genetic alterations that may contribute to luminal B breast cancer

Study sheds light on genetic alterations that may contribute to luminal B breast cancer

Researchers from the Lester and Sue Smith Breast Center at Baylor College of Medicine have uncovered new information about the genetic alterations that may contribute to the development of a subtype breast cancer typically associated with more aggressive forms of the disease and higher recurrence rates. [More]
Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results using FEI’s Titan Krios™ transmission electron microscope

Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results using FEI’s Titan Krios™ transmission electron microscope

FEI is pleased to announce that researchers at the NIH-FEI Living Lab for Structural Biology have achieved breakthrough biological results, using FEI’s Titan Krios™ transmission electron microscope (TEM), to elucidate the structural mechanism by which glutamate receptors participate in the transmission of signals between neurons in the brain. Their work is described in Nature, “Structural Mechanism of Glutamate Receptor Activation and Desensitization,” by Meyerson, et al., (DOI: 10.1038/nature13603), http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13603.html . [More]

Study shows that mice can identify specific odors amid complex olfactory environments

For many animals, making sense of the clutter of sensory stimuli is often a matter or literal life or death. Exactly how animals separate objects of interest, such as food sources or the scent of predators, from background information, however, remains largely unknown. [More]
Chronic obstructive pulmonary disease flare-ups: an interview with Dr. MeiLan Han, University of Michigan and Scott Cerreta, Director of Education, COPD Foundation

Chronic obstructive pulmonary disease flare-ups: an interview with Dr. MeiLan Han, University of Michigan and Scott Cerreta, Director of Education, COPD Foundation

During a flare-up, symptoms of a patient’s COPD worsen significantly, and breathing becomes more difficult. A persistent increase in shortness of breath, cough and sputum production are typical symptoms. [More]