Cerebrovascular Disease News and Research

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Cerebrovascular disease is a group of brain dysfunctions related to disease of the blood vessels supplying the brain. Hypertension is the most important cause; it damages the blood vessel lining, endothelium, exposing the underlying collagen where platelets aggregate to initiate a repairing process which is not always complete and perfect. Sustained hypertension permanently changes the architecture of the blood vessels making them narrow, stiff, deformed, uneven and more vulnerable to fluctuations in blood pressure.

Chiasma announces publication of octreotide capsules Phase III study results in JCEM

Chiasma Inc., a U.S. privately-held biopharma company, announced today that results from a multicenter Phase III study of the investigational new drug, octreotide capsules, were published online for early release on Feb. 9, ahead of print, by the Journal of Clinical Endocrinology & Metabolism.

10 Feb 2015

Vascular and Alzheimer's-related brain abnormalities cause dementia in older people

A growing body of research suggests that the most common cause of dementia in older people is a mix of vascular and Alzheimer's-related brain abnormalities, and that approximately half of people who die with Alzheimer's also have evidence of strokes in their brains. Furthermore, when strokes and hallmark Alzheimer's plaques and tangles are combined, it increases a person's likelihood of experiencing dementia.

15 Jan 2015

Lack of information increases depression risk in people recovering from stroke

People recovering from a stroke and living at home have generally a higher risk of suffering from depression. According to researchers lack of information is often a major concern for patients and this frequently contributes to their depression. This is the result of a new study from health sociologists of the University of Luxembourg.

12 Jan 2015

Hydroxyurea therapy offers safe, effective disease management of SCA

Conclusive data show that hydroxyurea therapy offers safe and effective disease management of sickle cell anemia (SCA) and reduces the risk of stroke, prompting early termination by the National Heart Lung and Blood Institute of a key clinical trial studying the drug's efficacy.

23 Nov 2014

Janssen announces submission of NDA for three-month paliperidone palmitate

Janssen Research & Development, LLC today announced the submission of a New Drug Application (NDA) for three-month atypical antipsychotic paliperidone palmitate to the U.S. Food and Drug Administration. The NDA seeks approval for the medication as a treatment for schizophrenia in adults.

19 Nov 2014

Impaired brain circulation in African Americans can increase risk of cerebrovascular disease

Researchers at The University of Texas have found that compared to Caucasian Americans, African Americans have impaired blood flow regulation in the brain that could contribute to a greater risk of cerebrovascular diseases such as stroke, transient ischaemic attack ("mini stroke"), subarachnoid haemorrhage or vascular dementia.

14 Nov 2014

Early brain imaging studies may help prevent vascular diseases

Future prevention and treatment strategies for vascular diseases may lie in the evaluation of early brain imaging tests long before heart attacks or strokes occur, according to a systematic review conducted by a team of cardiologists, neuroscientists, and psychiatrists from Icahn School of Medicine at Mount Sinai and published in the October issue of JACC Cardiovascular Imaging.

27 Oct 2014

UH's Neurological Institute designated as Gold Center of Excellence

The Neurological Institute at University Hospitals has been designated as a Gold Center of Excellence (COE) and featured as a top performing center by NeuStrategy, Inc., a Chicago consulting firm providing strategic support to neuroscience, oncology and orthopaedic service providers.

23 Oct 2014

Migraine in middle age linked to Parkinson's disease

A paper recently published in American Academy of Neurology suggests that migraine in middle age may indicate an increased risk of developing a movement disorder, such as Parkinson’s disease. The study also showed that people who experienced migraine with aura were twice as likely to develop Parkinson’s disease compared with those who did not suffer from headaches.

18 Sep 2014

FDA approves Contrave extended-release tablets for chronic weight management

Takeda Pharmaceuticals U.S.A., Inc. and Orexigen® Therapeutics, Inc. jointly announced today that the U.S. Food and Drug Administration has approved Contrave® extended-release tablets as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition.

11 Sep 2014

FDA approves Epaned for treatment of symptomatic and asymptomatic heart failure

Silvergate Pharmaceuticals, Inc., focused on the development and commercialization of innovative and safe medicines for children, today announced that the United States Food and Drug Administration approved Epaned for the treatment of symptomatic heart failure and the treatment of asymptomatic left ventricular dysfunction (to decrease the rate of development of overt heart failure and to reduce hospitalization for heart failure).

9 Sep 2014

Receiving prescription at discharge improves outcomes in stroke patients

Stroke patients are 70 per cent more likely to continue taking their stroke prevention medications one year later if they have a prescription in hand when discharged - according to researchers at St. Michael's Hospital and the Institute for Clinical Evaluative Sciences.

28 Aug 2014

People who develop depression, MCI after age 65 are more vulnerable for accelerated brain aging

People who develop depression and mild cognitive impairment (MCI) after age 65 are more likely to have biological and brain imaging markers that reflect a greater vulnerability for accelerated brain aging, according to a study conducted by researchers at the University of Pittsburgh School of Medicine. The findings were published online in Molecular Psychiatry.

8 Aug 2014

Patient goes on fishing trip after undergoing complex brain surgery

Just two weeks after undergoing delicate and complex brain surgery for a life-threatening condition, Bill Abt's surgeon cleared him to take a previously scheduled fishing trip.

9 Jul 2014

Fabry disease awareness: an interview with Dr. Hartmann Wellhoefer, Head of Medical Affairs, Rare Disease, Shire

Lysosomes are subcellular organelles that are present in most cells, with the major exception of red blood cells.

8 Jul 2014

Researchers confirm anecdotal information on Alzheimer's disease and cerebrovascular disease

Researchers from the Sanders-Brown Center on Aging at the University of Kentucky have been able to confirm anecdotal information on patients with both Alzheimer's disease (AD) and cerebrovascular disease (CVD) using mouse models in two different studies.

4 Jul 2014

Researchers confirm anecdotal information on patients with Alzheimer's disease, CVD

4 Jul 2014

Veterans with traumatic brain injury more likely to develop dementia in later life

Older veterans who have experienced a traumatic brain injury (TBI) are 60 percent more likely to later develop dementia than veterans without TBI, according to a study published in the June 25, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

25 Jun 2014

Penn researchers demonstrate new app to optimize acute stroke care

Stroke researchers from the Perelman School of Medicine at the University of Pennsylvania will unveil a map demonstrating geographic hotspots of increased stroke mortality across the United States, among a series of stroke studies being presented at the American Academy of Neurology's 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014.

29 Apr 2014

Heart problems less likely for spouses than for single people

People who are married have lower rates of several cardiovascular diseases compared with those who are single, divorced or widowed, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session. The relationship between marriage and lower odds of vascular diseases is especially pronounced before age 50.

29 Mar 2014