Chemokine News and Research

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Chemokines are a family of small cytokines, or proteins secreted by cells. Proteins are classified as chemokines according to shared structural characteristics such as small size (they are all approximately 8-10 kilodaltons in size), and the presence of four cysteine residues in conserved locations that are key to forming their 3-dimensional shape.

Primate model unlocks clues to long-COVID's impact on blood sugar, hints at vaccine benefits

The study uses a non-human primate model to explore the link between long-COVID and disruptions in glucose metabolism, finding a positive correlation. Vaccination appeared to improve glycemic control, suggesting a possible role in managing long-COVID symptoms.

28 Sep 2023

Could baseline gut microbiota predict the immune responses elicited by COVID-19 vaccines?

Researchers characterized the gut microbiota composition associated with the durability of COVID-19 vaccine-induced immunity.

27 Sep 2023

Researchers identify key regulators involved in genesis of multiple sclerosis lesions

By means of CRISPR screening, LMU researchers have provided the first ever comprehensive molecular characterization of T cell infiltration into the central nervous system of people with MS.

22 Sep 2023

Can COVID-19 vaccines turn the tide on long-haul symptoms?

The study finds that COVID-19 vaccination can significantly reduce symptoms and improve well-being in patients suffering from post-COVID-19 conditions (PCC). Vaccination also lowered systemic markers of inflammation but did not entirely eliminate persistent SARS-CoV-2 antigens, which may continue to contribute to inflammation.

22 Sep 2023

Early treatment with convalescent plasma may reduce risk of long COVID

Findings from a nationwide, multicenter study led by Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health suggest that patients with COVID-19 have less chance of developing post-COVID conditions -; commonly known as long COVID -; if they receive early treatment with plasma from convalescent (recovered) COVID patients that contain antibodies against SARS-CoV-2, the virus that causes COVID-19.

20 Sep 2023

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

18 Sep 2023

Reviving reservoirs: new findings shake up HIV treatment understanding

Researchers provide insight into the interaction between T lymphocytes and persisting reservoirs of HIV, with repercussions for harnessing effective, long-lasting responses to HIV eradication.

14 Sep 2023

Early sepsis detection: molecular immune markers show limited impact in screening tools

Researchers evaluated the additional predictive value of molecular immune markers with the Predict Sepsis screening tools developed previously by the same research team.

13 Sep 2023

Can yoga alleviate rheumatoid arthritis severity?

A recent Scientific Reports study investigated the effect of yoga on rheumatoid arthritis (RA) severity.

13 Sep 2023

Arf1 inhibition induces tumor regression by promoting T cell infiltration

In recent years, cancer immunotherapies, represented by immune checkpoint blockade (ICB), have been highly successful and have become an important basis for the future treatment of cancers.

12 Sep 2023

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Researchers conducted the phase 1 trial of orally-administered senolytic therapy comprising quercetin (Q) and dasatinib (D) for symptomatic and early-stage Alzheimer's disease (AD) patients.

8 Sep 2023

Rethinking menopause: Experts call for individualized treatment and more research

A comprehensive review in the journal Cell provides an in-depth look at the biology, clinical outcomes, and treatment options for menopause, including the effects of hormonal changes on metabolic and cognitive functions. The article also discusses various therapeutic interventions, from hormone therapy to alternative medicines, and their efficacy in managing menopausal symptoms.

7 Sep 2023

Eating for health: how dietary interventions impact pre-diabetic oral and gut microbiome, metabolites and cytokines

Researchers evaluated the impact of two diets on the intestinal and oral microbiota, cytokines, and metabolites of 200 pre-diabetic individuals.

7 Sep 2023

Immune cells can create their own chemical cues to navigate in complex environments

Human immune cells are capable of coordinating their own movement more independently than previously thought. InFLAMES researcher Jonna Alanko has discovered that immune cells do not just passively follow the chemical cues in their environment.

7 Sep 2023

Study sheds light on immune cells' ability to collectively migrate through complex environments

When fighting disease, our immune cells need to reach their target quickly. Researchers at the Institute of Science and Technology Austria (ISTA) now discovered that immune cells actively generate their own guidance system to navigate through complex environments.

1 Sep 2023

New 3D model mimics brain cell and immune cell interactions in Alzheimer's disease

Cognitive decline associated with Alzheimer's disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive inflammation in the brain triggered by amyloid beta deposits and tau tangles, two hallmarks of the disease.

25 Aug 2023

Chemokine News and Research

Further Reading

Primate model unlocks clues to long-COVID's impact on blood sugar, hints at vaccine benefits

Could baseline gut microbiota predict the immune responses elicited by COVID-19 vaccines?

Researchers identify key regulators involved in genesis of multiple sclerosis lesions

Can COVID-19 vaccines turn the tide on long-haul symptoms?

Early treatment with convalescent plasma may reduce risk of long COVID

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

Reviving reservoirs: new findings shake up HIV treatment understanding

Early sepsis detection: molecular immune markers show limited impact in screening tools

Can yoga alleviate rheumatoid arthritis severity?

Arf1 inhibition induces tumor regression by promoting T cell infiltration

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Rethinking menopause: Experts call for individualized treatment and more research

Eating for health: how dietary interventions impact pre-diabetic oral and gut microbiome, metabolites and cytokines

Immune cells can create their own chemical cues to navigate in complex environments

Study sheds light on immune cells' ability to collectively migrate through complex environments

New 3D model mimics brain cell and immune cell interactions in Alzheimer's disease

Study unveils how Cutibacterium acnes boosts epidermal lipids for enhanced barrier protection

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Identification of plasma proteins associated with ovarian cancer risk

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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