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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid. Cholesterol also comes from eating foods taken from animals such as egg yolks, meat, and whole-milk dairy products. Too much cholesterol in the blood may build up in blood vessel walls, block blood flow to tissues and organs, and increase the risk of developing heart disease and stroke.
UNMC researcher receives $3.3 million grant to study rare diseases that affect children

UNMC researcher receives $3.3 million grant to study rare diseases that affect children

University of Nebraska Medical Center researcher, William Rizzo, M.D., has received a five-year, $3.3 million grant to study 10 rare diseases that affect children beginning in infancy or early childhood and throughout their life. [More]
Low vitamin D levels linked to poor brain function after sudden cardiac arrest

Low vitamin D levels linked to poor brain function after sudden cardiac arrest

Vitamin D deficiency increases the risk of poor brain function after sudden cardiac arrest by seven-fold, according to research presented at Acute Cardiovascular Care 2014 by Dr Jin Wi from Korea. Vitamin D deficiency also led to a higher chance of dying after sudden cardiac arrest. [More]
Amgen files lawsuit against Regeneron, Sanofi to prevent infringing manufacture of alirocumab

Amgen files lawsuit against Regeneron, Sanofi to prevent infringing manufacture of alirocumab

Amgen today announced that it filed a lawsuit in the United States (U.S.) District Court of Delaware against Sanofi, Aventisub LLC, formerly doing business as Aventis Pharmaceuticals Inc. (collectively "Sanofi"), and Regeneron Pharmaceuticals, Inc. ("Regeneron") for patent infringement of U.S. Patent Numbers 8,563,698, 8,829,165, and 8,859,741. [More]
Potatoes can be part of a weight loss program, shows new study

Potatoes can be part of a weight loss program, shows new study

The study, a collaborative effort between the University of California at Davis and the Illinois Institute of Technology, sought to gain a better understanding of the role of calorie reduction and the glycemic index in weight loss when potatoes are included in the diet. [More]
Major scientific breakthrough in understanding retinal degenerative diseases that cause blindness

Major scientific breakthrough in understanding retinal degenerative diseases that cause blindness

An important scientific breakthrough by a team of IRCM researchers led by Michel Cayouette, PhD, is being published today by The Journal of Neuroscience. The Montréal scientists discovered that a protein found in the retina plays an essential role in the function and survival of light-sensing cells that are required for vision. [More]
Reducing heart failure deaths: an interview with Dimitrios Georgiopoulos, UK Medical Director, Novartis

Reducing heart failure deaths: an interview with Dimitrios Georgiopoulos, UK Medical Director, Novartis

Heart failure is a debilitating, and life-threatening, condition in which the heart cannot pump enough blood around the body. When heart failure continues to progress and worsen over time, the persistent condition is known as chronic heart failure. [More]
Cardiometabolic health intervention urged for schizophrenia patients

Cardiometabolic health intervention urged for schizophrenia patients

Research shows high cardiometabolic risk, particularly increased dyslipidaemia and smoking, but little related medical treatment in patients with first-episode schizophrenia. [More]
Astellas partners with Men's Health Network and USA Rugby to offer free health screenings

Astellas partners with Men's Health Network and USA Rugby to offer free health screenings

Astellas Pharma US, Inc., in partnership with USA Rugby and national patient advocacy organization Men's Health Network, will offer free health screenings and education around the historic match between the USA Eagles and the world champion New Zealand All Blacks rugby teams. [More]
Rockefeller University researchers gain new insight into how cholesterol processes in our body

Rockefeller University researchers gain new insight into how cholesterol processes in our body

In spite of its dangerous reputation, cholesterol is in fact an essential component of human cells. Manufactured by the cells themselves, it serves to stiffen the cell's membrane, helping to shape the cell and protect it. By mapping the structure of a key enzyme involved in cholesterol production, Rockefeller University researchers and a colleague in Italy have gained new insight into this complex molecular process. [More]
BIDMC scientists uncover new class of molecules that protects against diabetes

BIDMC scientists uncover new class of molecules that protects against diabetes

Scientists at the Salk Institute and Beth Israel Deaconess Medical Center in Boston have discovered a new class of molecules—produced in human and mouse fat—that protects against diabetes. [More]
TSRI research points toward new method for treating atherosclerosis

TSRI research points toward new method for treating atherosclerosis

Scientists at The Scripps Research Institute have created a synthetic molecule that mimics "good" cholesterol and have shown it can reduce plaque buildup in the arteries of animal models. The molecule, taken orally, improved cholesterol in just two weeks. [More]
VolitionRx announces additional colorectal cancer data at International Conference of Anticancer Research

VolitionRx announces additional colorectal cancer data at International Conference of Anticancer Research

VolitionRx Limited, a life sciences company focused on developing blood-based diagnostic tests, today announced that further data analysis from its colorectal cancer study was presented today at the 9th International Conference of Anticancer Research, being held October 6-10, 2014 in Sithonia, Greece. [More]
Magnesium essential to the activity of vitamin D

Magnesium essential to the activity of vitamin D

Extensive research has shown that vitamin D deficiencies play a major role in the development of dozens of diseases, including breast, prostate and colon cancer, as well as diabetes, heart disease, arthritis, osteoporosis, psoriasis and mental illness. [More]
Endocrine Society issues updated Clinical Practice Guideline on androgens in women

Endocrine Society issues updated Clinical Practice Guideline on androgens in women

The Endocrine Society today issued a Clinical Practice Guideline (CPG) advising against the use of testosterone therapy in healthy women. [More]
IRCM researchers discover mechanism that promotes progression of medulloblastoma

IRCM researchers discover mechanism that promotes progression of medulloblastoma

Scientists at the IRCM discovered a mechanism that promotes the progression of medulloblastoma, the most common brain tumour found in children. The team, led by Fr-d-ric Charron, PhD, found that a protein known as Sonic Hedgehog induces DNA damage, which causes the cancer to develop. [More]
Genetic susceptibility to psychosocial stress can increase risk of cardiovascular disease

Genetic susceptibility to psychosocial stress can increase risk of cardiovascular disease

A new genetic finding from Duke Medicine suggests that some people who are prone to hostility, anxiety and depression might also be hard-wired to gain weight when exposed to chronic stress, leading to diabetes and heart disease. [More]
Galmed Pharmaceuticals purchases EndoPAT devices, accessories from Itamar Medical

Galmed Pharmaceuticals purchases EndoPAT devices, accessories from Itamar Medical

Galmed Pharmaceuticals Ltd. ("Galmed"), a clinical-stage biopharmaceutical company focused on the development and commercialization of a once-daily, oral medication for the treatment of liver diseases and cholesterol gallstones, announced today that it purchased 60 EndoPAT™ devices and accessories from Itamar Medical Ltd. [More]
HerKare opens new location in Mansfield, Texas

HerKare opens new location in Mansfield, Texas

HerKare opens a new location today in Mansfield, Texas. This marks HerKare's third center in Dallas-Fort Worth. HerKare recently expanded to Houston area and continues to accelerate their growth plans, making the treatment of hormonal imbalance in women more convenient. [More]
Gastric bypass surgery provides better results than gastric banding

Gastric bypass surgery provides better results than gastric banding

Gastric bypass surgery has better outcomes than gastric banding for long-term weight loss, controlling type 2 diabetes and high blood pressure, and lowering cholesterol levels, according to a new review by UT Southwestern Medical Center surgeons of nearly 30 long-term studies comparing the two types of bariatric procedures. [More]
Metabolic abnormalities predict severe hypertension

Metabolic abnormalities predict severe hypertension

Components of the metabolic syndrome, as well as a family history of hypertension, identify people at risk of developing severe hypertension, say researchers. [More]