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Pew funds early-career scientists researching the basis of perplexing health problems

Pew funds early-career scientists researching the basis of perplexing health problems

Twenty-two of the nation's most enterprising researchers were named Pew Scholars in the Biomedical Sciences by The Pew Charitable Trusts today. The scholarships provide flexible funding to early-career scientists researching the basis of perplexing health problems such as diabetes, autism, Parkinson's disease, and cancer. [More]

Pew Charitable Trusts selects NYU professor as Pew Scholar in Biomedical Sciences

Fei Li, an assistant professor in New York University's Department of Biology, has been selected as a Pew Scholar in the Biomedical Sciences by The Pew Charitable Trusts. [More]
Virginia Tech's Chang Lu awarded new NIH grant to research on cancer

Virginia Tech's Chang Lu awarded new NIH grant to research on cancer

Progress made in the technology development for studying protein-DNA interactions, conducted by Chang Lu, associate professor of chemical engineering and a core faculty member of the School of Biomedical Engineering and Sciences at Virginia Tech, has led to the National Institutes of Health (NIH) awarding a new project to continue his groundbreaking work. [More]
Discovery of impaired molecular pathway may help treat children with leukemia

Discovery of impaired molecular pathway may help treat children with leukemia

Through genetic engineering of laboratory models, researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center have uncovered a vulnerability in the way cancer cells diverge from normal regenerating cells that may help treat children with leukemia as reported in the journal PNAS on June 3, 2013. [More]
Researchers identify a new mechanism that appears to suppress tumor growth

Researchers identify a new mechanism that appears to suppress tumor growth

Researchers at the University of California, San Diego School of Medicine, with colleagues at the University of Rochester Medical Center, have identified a new mechanism that appears to suppress tumor growth, opening the possibility of developing a new class of anti-cancer drugs. [More]

Chromatrap® ChIP assay kit enriches epigenetic marks from primary human tissue cells

A new application note from Porvair Sciences details a protocol for its Chromatrap® ChIP assay kit that has been developed to enrich epigenetic marks from primary human tissue cells. [More]
Researchers identify mutations in new genes that might be associated with ALS disease

Researchers identify mutations in new genes that might be associated with ALS disease

Researchers at the Stanford University School of Medicine have identified mutations in several new genes that might be associated with the development of spontaneously occurring cases of the neurodegenerative disease known as amyotrophic lateral sclerosis, or ALS. [More]
Vijay Tiwari from IMB receives Bruno Speck Award from Swiss Foundation of Haematological Research

Vijay Tiwari from IMB receives Bruno Speck Award from Swiss Foundation of Haematological Research

Dr Vijay Tiwari, a Group Leader at the Institute of Molecular Biology (IMB) in Mainz, has been awarded the Bruno Speck Award by the Swiss Foundation of Haematological Research. The award recognises outstanding work by young scientists in the fields of haematology and stem cell research. [More]
Modifications in key epigenetic markers influence human embryonic stem cells

Modifications in key epigenetic markers influence human embryonic stem cells

Scientists have long known that control mechanisms known collectively as "epigenetics" play a critical role in human development, but they did not know precisely how alterations in this extra layer of biochemical instructions in DNA contribute to development. [More]
Gene offers new insights into treatment strategies for deep-vein thrombosis

Gene offers new insights into treatment strategies for deep-vein thrombosis

A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep-vein thrombosis -- the formation of a harmful clot in a deep vein. [More]
Researchers find deficiency in anti-tumor protein can delay DNA repair after radiation treatment

Researchers find deficiency in anti-tumor protein can delay DNA repair after radiation treatment

Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression of two enzymes (JMJD2b and SUV39H1) that control the folding of DNA. [More]
National Jewish Health researchers unravel mystery of adjuvants

National Jewish Health researchers unravel mystery of adjuvants

Aluminum salts, or alum, have been injected into billions of people as an adjuvant to make vaccines more effective. [More]
Study links mutated histone protein to rare brain stem cancer in children

Study links mutated histone protein to rare brain stem cancer in children

Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. [More]
Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Inflammation can be thought of as taking two major forms: acute or chronic. Acute inflammation, which can be painful, usually arises quickly and resolves quickly. It accompanies bacterial infections, traumatic injury and is useful to fight infections and promote healing. [More]
Chromatrap chromatin immunoprecipitation (ChIP) assay range added to Porvair Sciences’ portfolio of products for epigenetics

Chromatrap chromatin immunoprecipitation (ChIP) assay range added to Porvair Sciences’ portfolio of products for epigenetics

Porvair Sciences has announced the addition of the novel Chromatrap chromatin immunoprecipitation (ChIP) assay range to its portfolio of products for epigenetics. [More]

UCI study finds novel molecular mechanism that helps trigger formation of long-term memory

UC Irvine neurobiologists have found a novel molecular mechanism that helps trigger the formation of long-term memory. The researchers believe the discovery of this mechanism adds another piece to the puzzle in the ongoing effort to uncover the mysteries of memory and, potentially, certain intellectual disabilities. [More]
Protein with key job in muscle function moonlights in nucleus to help regulate genes

Protein with key job in muscle function moonlights in nucleus to help regulate genes

A key building block of life, actin is one of the most abundant and highly conserved proteins in eukaryotic cells. [More]

Study uncovers new relationship between nuclear architecture, gene activity

Every time a cell divides it makes a carbon copy of crucial ingredients, including the histone proteins that are responsible for spooling yards of DNA into tight little coils. [More]
Cocaine can be lethal for people living with HIV

Cocaine can be lethal for people living with HIV

Cocaine, already a damaging drug for those with healthy immune systems, can be lethal for those living with human immunodeficiency virus. Mudit Tyagi, Ph.D., assistant professor of medicine at the George Washington University School of Medicine and Health Sciences, has received two federally funded grants to study how dangerous this combination is in HIV patients. [More]
Chroma Therapeutics, CTI announce results from tosedostat Phase 2 study on AML

Chroma Therapeutics, CTI announce results from tosedostat Phase 2 study on AML

Cell Therapeutics, Inc. (CTI) and Chroma Therapeutics Ltd. announced today that Lancet Oncology has published results from the OPAL Phase 2 study of tosedostat in elderly patients with relapsed or refractory acute myeloid leukemia (AML). [More]