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Engineers develop tools to efficiently analyze living cells

Engineers develop tools to efficiently analyze living cells

For more than a decade Chang Lu, associate professor of chemical engineering at Virginia Tech, has worked on the development of tools to efficiently analyze living cells. The long-term goal is to gain a better understanding of a range of diseases. [More]

Covaris' European subsidiary to commence operations on May 1, 2014

Covaris, Inc., an innovator in the life science tools and the clinical diagnostic market spaces, announced today that its European subsidiary, Covaris Ltd, which is located in the United Kingdom, will commence operations on May 1, 2014. [More]
Nanostring Technologies launches nCounter PanCancer Pathways Panel

Nanostring Technologies launches nCounter PanCancer Pathways Panel

NanoString Technologies, Inc., (NASDAQ:NSTG) a provider of life science tools for translational research and molecular diagnostic products, today announced the launch of the nCounter® PanCancer Pathways Panel, a highly-multiplexed, digital gene expression assay that offers a unique way for translational researchers to investigate cancer biology across all major cancer pathways. [More]
Sanford-Burnham to present new cancer research data at AACR 2014

Sanford-Burnham to present new cancer research data at AACR 2014

Sanford-Burnham Medical Research Institute will present a wide range of new research data at the annual American Association for Cancer Research Meeting in San Diego starting Saturday, April 5, at the San Diego Convention Center. The presentations will cover a variety of topics including breast, melanoma, and prostate cancer, as well as novel methods of delivering drugs to tumors. [More]
Scientists unlock one of mysteries of modern genetics

Scientists unlock one of mysteries of modern genetics

Scientists at Indiana University have unlocked one of the mysteries of modern genetics: how acquired traits can be passed between generations in a process called epigenetic inheritance. The new work finds that cells don't know to silence some genes based on information hardwired into their DNA sequences, but recognize heritable chemical marks that are added to the genes. These chemical tags serve as a form of molecular memory, allowing cells to recognize the genes and remember to silence them again in each new generation. [More]

Researchers identify steps by which cell removes RNA from cytoplasm

RNA encodes the proteins that play a key role in cellular reproduction, but the manner in which cells regulate its removal once these proteins are synthesized remains a mystery. One piece of this mystery has been solved as researchers at the University of North Carolina at Chapel Hill who have identified the steps by which a cell removes RNA from the cytoplasm. [More]

ChromaTrap™ Chromatin Immunoprecipitation technology receives positive commentary in published paper

Porvair Sciences reports on positive commentary by researchers in published papers citing how using the fast, sensitive ChromaTrap™ Chromatin Immunoprecipitation (ChIP) technology has benefited their research. [More]

Researchers identify high-speed cellular transport mechanism

Our DNA and its architecture are duplicated every time our cells divide. Histone proteins are key building blocks of this architecture and contain crucial information that regulates our genes. Danish researchers show how an enzyme controls reliable and high-speed delivery of histones to DNA copying hubs in our cells. This shuttling mechanism is crucial to maintain normal function of our genes and prevent disease. The results are published in the journal Nature Communications. [More]
Scientists uncover key mechanism of gene regulation

Scientists uncover key mechanism of gene regulation

In the cells of humans and other organisms, only a subset of genes are active at any given time, depending largely on the stage of life and the particular duties of the cell. Cells use different molecular mechanisms to orchestrate the activation and deactivation of genes as needed. [More]

Study identifies promising target for new drugs to treat lethal form of brain cancer

A molecule in cells that shuts down the expression of genes might be a promising target for new drugs designed to treat the most frequent and lethal form of brain cancer, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute. [More]
Study identifies enzyme with key role in precancerous lesions

Study identifies enzyme with key role in precancerous lesions

Cancer of the pancreas is usually not detected until it's too late to cure. But precursor lesions that form in the pancreas and its ducts can signal the disease before it strikes, and when caught early enough, they can be prevented from progressing to become cancer. [More]

Researchers develop new technology that reveals secrets of cellular memory

Cells in our body are constantly dividing to maintain our body functions. At each division, our DNA code and a whole machinery of supporting components has to be faithfully duplicated to maintain the cell's memory of its own identity. [More]
Subtle epigenetic change plays important role in correct segregation of chromosomes

Subtle epigenetic change plays important role in correct segregation of chromosomes

Abnormal number of chromosomes is often associated with cancer development. In a new study published in the journal Nature Structural and Molecular Biology researchers at Karolinska Institutet in Sweden have shown that a subtle epigenetic change plays an important role in the correct segregation of chromosomes. [More]
Researchers discover promising new approach for leukemia treatment

Researchers discover promising new approach for leukemia treatment

A group of researchers at the Institute for Research in Immunology and Cancer of Universit- de Montr-al discovered a promising new approach to treating leukemia by disarming a gene that is responsible for tumor progression. That gene, known as Brg1 is a key regulator of leukemia stem cells that are the root cause of the disease, resistance to treatment and relapse. [More]

Porvair Sciences to showcase specialist microplate products at Pittcon, Analytica and Genomics Research 2014

Porvair Sciences has announced that it will be showing its latest specialist microplates and microplate equipment at the forthcoming Pittcon 2014 (Chicago), Analytica 2014 (Munich) and Genomics Research 2014 (San Francisco) exhibitions. [More]
Researchers identify histone proteins that may be key to generate induced totipotent stem cells

Researchers identify histone proteins that may be key to generate induced totipotent stem cells

One major challenge in stem cell research has been to reprogram differentiated cells to a totipotent state. Researchers from RIKEN in Japan have identified a duo of histone proteins that dramatically enhance the generation of induced pluripotent stem cells (iPS cells) and may be the key to generating induced totipotent stem cells. [More]
TCGA Research Network identify new potential therapeutic targets for major form of bladder cancer

TCGA Research Network identify new potential therapeutic targets for major form of bladder cancer

Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified new potential therapeutic targets for a major form of bladder cancer, including important genes and pathways that are disrupted in the disease. [More]
Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

The once sketchy landscape of the molecular defects behind bladder cancer now resembles a road map to new, targeted treatments thanks to the unified efforts of scientists and physicians at 40 institutions. [More]

Researcher receives 2014 Japan Prize in Life Sciences for extraordinary work in the field of epigenetics

C. David Allis, a pioneer in the field of epigenetics whose discovery that chemical modifications of DNA-packaging proteins play a key role in regulating the activity of individual genes, will be awarded the 2014 Japan Prize in Life Sciences. The announcement, by the Japan Prize Foundation, was made at a press conference in Tokyo this morning. [More]
New Chromatrap Enzymatic Shearing Kit announced by Porvair Sciences

New Chromatrap Enzymatic Shearing Kit announced by Porvair Sciences

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