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EMD Millipore launches Magna ChIRP RNA Interactome Kits for analyzing chromatin-associated RNAs

EMD Millipore launches Magna ChIRP RNA Interactome Kits for analyzing chromatin-associated RNAs

EMD Millipore, the Life Science business of Merck KGaA of Darmstadt, Germany, today introduced Magna ChIRP™ RNA Interactome Kits, which allow researchers to more easily identify, recover and analyze regions of chromatin that interact with chromatin-associated RNAs such as long non-coding RNA (lncRNA). [More]
Winners of GSA poster awards announced at 56th Annual Drosophila Research Conference

Winners of GSA poster awards announced at 56th Annual Drosophila Research Conference

The Genetics Society of America (GSA) and the Drosophila research community are pleased to announce the winners of the GSA poster awards at the 56th Annual Drosophila Research Conference, which took place in Chicago, IL, March 4-8, 2015. [More]
Researchers use new gene editing tool to cut HIV DNA

Researchers use new gene editing tool to cut HIV DNA

The virus that causes AIDS is an efficient and crafty retrovirus. Once HIV inserts its DNA into the genome of its host cells, it has a long incubation period, and can remain dormant and hidden for years. [More]
High Throughput ChIP Sequencing

High Throughput ChIP Sequencing

Chromatrap®, a business unit of Porvair Sciences, has announced a major product launch at the European Human Genetics Conference (Glasgow, UK) and the Festival of Genomics (Boston, USA) on the 6th June 2015 and 22nd-24th June 2015 respectively [More]
Study finds link between neurodegenerative disorders and inflammation

Study finds link between neurodegenerative disorders and inflammation

Researchers from McMaster University and the Icahn School of Medicine at Mount Sinai, New York have discovered that a protein associated with neurodegenerative diseases like ALS also plays an important role in the body's natural antiviral response. [More]
CSHL professor to be honored with AACR Outstanding Achievement in Cancer Research Award

CSHL professor to be honored with AACR Outstanding Achievement in Cancer Research Award

The American Association for Cancer Research will honor Christopher R. Vakoc, MD, PhD, assistant professor at Cold Spring Harbor Laboratory in Cold Spring Harbor, New York, with the 35th annual AACR Outstanding Achievement in Cancer Research Award at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22. [More]
Arno Therapeutics' AR-42 with cisplatin demonstrates anti-tumor effect in bladder cancer models

Arno Therapeutics' AR-42 with cisplatin demonstrates anti-tumor effect in bladder cancer models

Arno Therapeutics, Inc., a clinical stage biopharmaceutical company primarily focused on the development of oncology therapeutics, today announced that data from a preclinical study demonstrate its histone-deacetylase (HDAC) inhibitor AR-42 in combination with cisplatin has a synergistic anti-tumor effect in bladder cancer models. [More]
Biological clue could help explain why some drinkers can't resist alcohol

Biological clue could help explain why some drinkers can't resist alcohol

Virginia Commonwealth University School of Medicine researchers have discovered a biological clue that could help explain why some drinkers develop a dependence on alcohol and others do not. [More]
Super-resolution microscopes reveal the link between genome packaging and cell pluripotency

Super-resolution microscopes reveal the link between genome packaging and cell pluripotency

In 1953 Watson and Crick first published the discovery of the double helix structure of the DNA. They were able to visualize the DNA structure by means of X-Ray diffraction. Techniques, such as electron microscopy, allowed scientists to identify nucleosomes, the first and most basic level of chromosome organisation [More]
McGill researchers discover key epigenetic factor that controls development of hippocampus

McGill researchers discover key epigenetic factor that controls development of hippocampus

McGill researchers have discovered, for the first time, the importance of a key epigenetic regulator in the development of the hippocampus, a part of the brain associated with learning, memory and neural stem cells. [More]
Developments in ChIP technology

Developments in ChIP technology

Biowales, one of the UK’s leading events for the life sciences sector, this year will focus on the life sciences supply chain providing practical commercial opportunities for growth through novel routes to market in the private sector and National Health Service (NHS). [More]
Study provides new insights into early events that shape cancer

Study provides new insights into early events that shape cancer

A study led by researchers from Brigham and Women's Hospital suggests a new way to trace cancer back to its cell type of origin. By leveraging the epigenome maps produced by the Roadmap Epigenomics Program - a resource of data collected from over 100 cell types - the research team found that the unique genetic landscape of a particular tumor could be used to predict that tumor's cell type of origin. [More]
New facts provide baseline for future studies of epigenome's role in human development, diseases

New facts provide baseline for future studies of epigenome's role in human development, diseases

While genomics is the study of all of the genes in a cell or organism, epigenomics is the study of all the genomic add-ons and changes that influence gene expression but aren't encoded in the DNA sequence. A variety of new epigenomic information is now available in a collection of studies published Feb. 19 in Nature by the National Institutes of Health Roadmap Epigenomics Program. [More]
Cabazitaxel therapy may be more effective in treating prostate cancer

Cabazitaxel therapy may be more effective in treating prostate cancer

Prostate cancer is the second leading cause of cancer for men in the United States. Only one class of chemotherapy called taxanes is effective against the disease. [More]
Wistar researchers identify new therapeutic target for aggressive form of ovarian cancer

Wistar researchers identify new therapeutic target for aggressive form of ovarian cancer

Ovarian cancer is the deadliest of all cancers affecting the female reproductive system with very few effective treatments available. Prognosis is even worse among patients with certain subtypes of the disease. Now, researchers at The Wistar Institute have identified a new therapeutic target in a particularly aggressive form of ovarian cancer, paving the way for what could be the first effective targeted therapy of its kind for the disease. [More]
Study provides common model of cellular ageing

Study provides common model of cellular ageing

Researchers at the BBSRC-supported Babraham Institute have mapped the physical structure of the nuclear landscape in unprecedented detail to understand changes in genomic interactions occurring in cell senescence and ageing. Their findings have allowed them to reconcile the contradictory observations of two current models of ageing: cellular senescence of connective tissue cells called fibroblasts and cellular models of an accelerated ageing syndrome. [More]
Damon Runyon Cancer Research Foundation names 15 new Damon Runyon Fellows

Damon Runyon Cancer Research Foundation names 15 new Damon Runyon Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 15 new Damon Runyon Fellows at its fall Fellowship Award Committee review. The recipients of this prestigious, four-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators across the country. [More]
Hutchinson-Gilford Progeria Syndrome can be compared to normal aging, say scientists

Hutchinson-Gilford Progeria Syndrome can be compared to normal aging, say scientists

In a new research study, scientists from Vision Genomics, LLC, Insilico Medicine, Inc., and Howard University showed that Hutchinson-Gilford Progeria Syndrome (HGPS or Progeria) is comparable to normal aging with respect to cellular signaling pathways, and that HGPS truly recapitulates the normal aging process. [More]
Chromatrap announce solid state ChIP kits

Chromatrap announce solid state ChIP kits

Chromatrap®, a business unit of Porvair Sciences, has an announced solid state ChIP kits which rapidly improve chromatin immunoprecipitation (ChIP) through a unique patented technology that streamlines the process, ensuring chromatin preparation to qPCR analysis can be performed in under five hours. [More]
New opportunity for developing simple test to measure E2F4 activity in ER+ breast cancer patients

New opportunity for developing simple test to measure E2F4 activity in ER+ breast cancer patients

By looking at the expression levels of downstream genes of the regulators in breast cancer, investigators at Dartmouth Hitchcock's Norris Cotton Cancer Center, led by Chao Cheng, PhD, have identified a gene signature in E2F4 that is predictive of estrogen receptor positive (ER+) breast cancer. [More]
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