Cilia News and Research

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COVID-19 and loss of sense of smell

A recent review examines the high susceptibility of the olfactory epithelium to SARS-CoV-2 infection.

9 Nov 2021

Researchers identify γ-tubulin ring complex to be responsible for providing centriole stability

Centrioles are cylindrical structures involved in the generation of microtubules-;fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes.

1 Nov 2021

Could vitamin A help to regain your smell loss after COVID-19?

Could vitamin A help to regain your smell after COVID-19? New research is trying to find out, and we spoke exclusively to Professor Carl Philpott to find out more.

29 Sep 2021

Study pinpoints an entirely new approach for treatment of biliary atresia

Biliary atresia is the largest cause of end-stage liver fibrosis in children and the main reason children need liver transplants. Despite many years of worldwide research, scientists have not yet found a way to prevent the condition.

7 Sep 2021

Optical nanoscopy reveals how SARS-CoV-2 infection alters human airway cells

How do viruses reorganize host cells with spatial and molecular specificity? Researchers from the Netherlands provided new insights in a recent study posted to the bioRxiv* preprint server, where they use optical nanoscopy to look at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-triggered changes in primary human airway cells.

12 Aug 2021

Novel model describes the coordination of beating cilia

A new model describes the coordination of beating cilia allowing to predict their functional behavior.

10 Aug 2021

Study uncovers link between corticosteroid receptors and ciliary, neuroplasticity genes in the brain

Chronic stress is a well-known cause for mental health disorders. New research has moved a step forward in understanding how glucocorticoid hormones ('stress hormones') act upon the brain and what their function is.

6 Aug 2021

Scientists explore susceptibility of different animals to SARS-CoV-2 infection

A team of researchers at the Institute of Infectious Diseases (IFIK) at the University of Bern and the Institute of Virology and Immunology (IVI) has utilized a unique collection of advanced cell culture models of cells lining the airways from various domesticated and wildlife animals. This way, the team can determine which animals are susceptible to SARS-CoV-2 infection.

20 Jul 2021

Inhibition of SARS-CoV-2 by bentonite-based nasal spray

Therefore, the nose is an important target for prophylaxis and also for therapy. In a recent study posted to the bioRxiv* preprint server, Fabio Fais et al. developed a safe and easy-to-use nasal spray, AM-301, a medical device marketed as Bentrio, to protect against infection by SARS-CoV-2 and potentially other viruses.

19 Jul 2021

Eggs and embryos go through a more dynamic and complex journey than previously thought

The journey of the egg and the embryo through the fallopian tube or oviduct toward the uterus is not well understood, mainly because it is inaccessible for direct imaging.

14 Jul 2021

Researchers gain new insights into the pathology of Usher syndrome

Human Usher syndrome (USH) is the most common form of hereditary deaf-blindness. Sufferers can be deaf from birth, suffer from balance disorders, and eventually lose their eyesight as the disease progresses.

12 Jul 2021

New study on swine influenza virus may be relevant to influenza, coronavirus infection in humans

A new study carried out in pig cells suggests previous infection with swine influenza virus (SIV) can protect against the development of porcine respiratory coronavirus (PRCoV) if there is a zero- or three-day interval between infections.

2 Jun 2021

Study on canine hereditary deafness may also shed light on human hereditary hearing defects

Finnish researchers have been the first to determine the cause for the nonsyndromic early-onset hereditary canine hearing loss in Rottweilers.

22 May 2021

Study: Repeated vape aerosol exposure causes minimal lung damage compared to combustible cigarettes

In one of the most advanced applications of in-vitro 3D human lung models in vape research to date, a new peer-reviewed Imperial Brands study shows that, unlike combustible cigarette smoke, blu aerosol had little to no impact on numerous toxicological endpoints under the conditions of test using laboratory models.

6 May 2021

What happens in the first few days of SARS-CoV-2 infection?

New research, published in PLOS Biology, has evaluated SARS-CoV-2 infection in primary cultures of well-differentiated cells to determine how the virus affects the body and how the infection starts. Answers to these questions are essential to forming a general understanding of viral pathogenesis, which helps us develop effective prevention and treatment strategies for COVID-19.

4 May 2021

Biology of single-celled organisms reveals potential treatment target for COPD

In a series of experiments that began with amoebas -- single-celled organisms that extend podlike appendages to move around -- Johns Hopkins Medicine scientists say they have identified a genetic pathway that could be activated to help sweep out mucus from the lungs of people with chronic obstructive pulmonary disease a widespread lung ailment.

13 Apr 2021

Researchers identify new potential mechanism for age-related macular degeneration

Using laboratory-grown roundworms as well as human and mouse eye tissue, University of Maryland School of Medicine (UMSOM) researchers have identified a new potential mechanism for age-related macular degeneration-;the leading cause of blindness among older adults.

13 Apr 2021

Researchers provide ultrastructural details of SARS-CoV-2-infected respiratory epithelial cells

A team of scientists from the United Kingdom recently investigated the ultrastructural details of the attachment, entry, and budding processes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the human airway epithelium. They have used a highly differentiated air-liquid interface cultures of airway epithelium to thoroughly investigate the viral infection cycle. The study is currently available on the bioRxiv* preprint server.

12 Apr 2021

Single injection of RNA therapy improves vision in patient with genetic form of childhood blindness

A Penn Medicine patient with a genetic form of childhood blindness gained vision, which lasted more than a year, after receiving a single injection of an experimental RNA therapy into the eye.

1 Apr 2021

Temperature difference in the upper and lower respiratory tract influences SARS-CoV-2 replication

A team of researchers from the Institute for Infectious Diseases (IFIK) at the University of Bern and the Federal Institute of Virology and Immunology (IVI) have assessed virus growth and activation of the cellular defense mechanisms in the respiratory tract.