Clinical Trial News and Research RSS Feed - Clinical Trial News and Research

Study highlights lack of guidance on deintensifying diabetic regimens

Study highlights lack of guidance on deintensifying diabetic regimens

Patients with Type 2 diabetes often receive unnecessarily intensive treatment for long durations, increasing their risk of severe hypoglycaemia, research shows. [More]
Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Potent doses of broccoli sprout extract activate a "detoxification" gene and may help prevent cancer recurrence in survivors of head and neck cancer, according to a trial by the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter, confirming preliminary results presented last year at the American Association for Cancer Research Annual Meeting. [More]
SLU to conduct human clinical trial of vaccine to protect people from Zika virus

SLU to conduct human clinical trial of vaccine to protect people from Zika virus

Saint Louis University's vaccine center has been tapped by the National Institutes of Health to conduct a human clinical trial of a vaccine to prevent the Zika virus, which can cause devastating birth defects in babies. [More]
Study compares efficacy of SDF in arresting root caries in elders from different fluoridated areas

Study compares efficacy of SDF in arresting root caries in elders from different fluoridated areas

On June 24, 2016, at the 94th General Session & Exhibition of the International Association for Dental Research, researcher Edward Lo, University of Hong Kong, SAR, China, will present a study titled "Effectiveness of SDF in Arresting Root Caries in Different Fluoridated Areas." [More]
Could artificial intelligence help to combat stress? An interview with Davide Morelli

Could artificial intelligence help to combat stress? An interview with Davide Morelli

Stress is actually a bit of a buzzword. The initial definition was “the reaction to changes”, which is why you get stressed also when good things happen, hence the distinction between good stress, eustress, and bad stress, distress. [More]
Two gene variants provide clue to why some patients with PD respond well to rasagiline drug

Two gene variants provide clue to why some patients with PD respond well to rasagiline drug

Researchers have identified a gene variant which explains why some patients with Parkinson's Disease respond well to drug treatment and other do not. [More]
Novel combination therapy slows cancer growth in patients with advanced solid tumors

Novel combination therapy slows cancer growth in patients with advanced solid tumors

A phase 1 clinical trial testing a novel combination therapy developed by scientists at VCU Massey Cancer Center slowed the growth of cancer in the majority of trial participants, which were patients with advanced solid tumors. [More]
Real-world analysis questions very low LDL targets

Real-world analysis questions very low LDL targets

Patients treated for hypercholesterolaemia in clinical practice may not derive additional benefit from very intensive statin treatment, say researchers. [More]
Protein-based CHD risk score developed

Protein-based CHD risk score developed

Researchers have screened over 1000 plasma proteins to develop a predictive score in patients with stable coronary heart disease. [More]
New CAR-based therapy using combined cancer target could be effective for solid tumors

New CAR-based therapy using combined cancer target could be effective for solid tumors

Chimeric antigen receptors (CARs), engineered from a patient's own immune cells, have been successful for treating blood cancers, but using CARs for solid tumors has been limited by side effects to normal tissues containing the protein targeted by the engineered cells. [More]
VUMC researchers aim to decode genetic underpinnings of human immune system

VUMC researchers aim to decode genetic underpinnings of human immune system

Researchers at Vanderbilt University Medical Center this month began recruiting volunteers to participate in a clinical trial aimed at decoding the human "immunome," the genetic underpinnings of the immune system. [More]
Clinical trial finds pioglitazone drug safe and effective for NASH patients

Clinical trial finds pioglitazone drug safe and effective for NASH patients

Researchers have found that an existing diabetes drug can be used to halt progression of another disease that is a leading cause of liver transplants. [More]
Patient navigators could help improve comprehensive cancer screening rates among low-income, ethnic minorities

Patient navigators could help improve comprehensive cancer screening rates among low-income, ethnic minorities

A clinical trial conducted by Massachusetts General Hospital investigators has found that the use of patient navigators - individuals who assist patients in receiving health care services - may improve comprehensive cancer screening rates among patient populations not likely to receive recommended screenings. [More]
Scientific paper supports concept of CarThera's intracranial ultrasound implant to disrupt blood-brain barrier

Scientific paper supports concept of CarThera's intracranial ultrasound implant to disrupt blood-brain barrier

CarThera, a French company based at the Brain and Spine Institute, that designs and develops innovative ultrasound-based medical devices to treat brain disorders, today announces the publication in Science Translational Medicine of a scientific paper on initial successes in disrupting the blood-brain barrier (BBB) with the use of ultrasound. [More]
Nonopioid interventional options for chronic pain not covered by insurance in few U.S. states

Nonopioid interventional options for chronic pain not covered by insurance in few U.S. states

Recent studies have shown significant therapeutic value from the use of high-frequency - 10,000 (HF-10) spinal cord stimulation (SCS) for patients experiencing chronic back and leg pain. [More]
New collaborative research program connects canine and human cancers

New collaborative research program connects canine and human cancers

A new collaborative research program pairs oncologists who treat childhood and adult sarcomas with veterinarians who manage the same cancers in canine patients. [More]
Surgical treatment more effective than medical therapy for treating severely obese adolescents

Surgical treatment more effective than medical therapy for treating severely obese adolescents

An analysis of the results of a study of bariatric surgery and a separate trial of medical therapy in treating type 2 diabetes in teenagers with severe obesity shows that after two years of treatment, body mass index (BMI) and HbA1c, a measure of blood sugar control, are both significantly better with surgery. [More]
'Nonserious' side effects may lead to antiplatelet discontinuation

'Nonserious' side effects may lead to antiplatelet discontinuation

Most adverse events that lead patients to discontinue antiplatelet drugs are not rated as serious by clinical trial criteria, shows analysis of the PEGASUS-TIMI 54 trial. [More]
Cerebral vessel disease increases Alzheimer's dementia risk

Cerebral vessel disease increases Alzheimer's dementia risk

Cerebral vessel disease may be an under-recognised risk factor for Alzheimer's disease dementia, say researchers. [More]
Diet modification could help improve quality of life in women with ovarian cancer

Diet modification could help improve quality of life in women with ovarian cancer

New research conducted at the University of Alabama at Birmingham has shown that a particular type of diet could help women with ovarian cancer to lose weight and improve their quality of life and cancer-related measures. [More]
Advertisement
Advertisement