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Researchers find new way to increase patients’ recruitment, retention in clinical trials

Researchers find new way to increase patients’ recruitment, retention in clinical trials

By seeking the advice of patients, families and other stakeholders in designing a clinical trial investigating pediatric appendicitis, researchers at Nationwide Children's Hospital found a way to significantly increase the number of people recruited and retained in the trial. [More]
Ultrasound-activated microbubbles help preserve healthy heart tissue

Ultrasound-activated microbubbles help preserve healthy heart tissue

Researchers funded by the National Institute of Biomedical Imaging and Bioengineering used ultrasound-activated microbubbles to improve preservation of heart muscle and function in a pig heart attack model. [More]
Modulation of opioid system may improve effectiveness of drugs for treatment-resistant depression

Modulation of opioid system may improve effectiveness of drugs for treatment-resistant depression

A clinical trial of an experimental drug for treatment-resistant major depression finds that modulation of the endogenous opioid system may improve the effectiveness of drugs that target the action of serotonin and related monoamine neurotransmitters. [More]
Liverpool researchers reach major milestone towards creating diagnostic test for prostate cancer

Liverpool researchers reach major milestone towards creating diagnostic test for prostate cancer

A research team from the University of Liverpool has reached an important milestone towards creating a urine diagnostic test for prostate cancer that could mean that invasive diagnostic procedures that men currently undergo eventually become a thing of the past. [More]
Neurocrine Biosciences reports net loss of $29.3 million for fourth quarter 2015

Neurocrine Biosciences reports net loss of $29.3 million for fourth quarter 2015

Neurocrine Biosciences, Inc. today announced its financial results for the quarter and year ended December 31, 2015. [More]
ASTRO's new research journal 'Advances in Radiation Oncology' closes first issue

ASTRO's new research journal 'Advances in Radiation Oncology' closes first issue

Advances in Radiation Oncology, ASTRO's new original research journal, has closed its first issue with research including a phase II clinical trial in prostate cancer, a prospective trial in quality of life for breast cancer patients receiving radiotherapy and several clinical and medical physics reports on the use of stereotactic body radiotherapy. [More]
Novel test could help get best treatment for advanced bowel cancer patients

Novel test could help get best treatment for advanced bowel cancer patients

A NEW test could help patients with advanced bowel cancer get the best treatment for their disease, according to a Cancer Research UK clinical trial published today (Thursday) in JAMA Oncology. [More]
Oral therapeutic drug shows promise against recurrent C. difficile infection

Oral therapeutic drug shows promise against recurrent C. difficile infection

Results from a Phase 1b/2 trial suggest that an investigational microbiome-based, oral therapeutic drug is effective for the treatment of recurrent C. difficile infection. In a paper published online in the Journal of Infectious Diseases, a multi-institutional research team reports that treatment with the preparation, containing the spores of approximately 50 species of beneficial bacteria, successfully prevented recurrence of C. difficile infection (CDI) in patients with a history of multiple recurrent disease. [More]
UC San Diego School of Medicine launches new NAFLD Research Center

UC San Diego School of Medicine launches new NAFLD Research Center

Roughly one-quarter of all Americans - an estimated 100 million adults and children - have nonalcoholic fatty liver disease (NAFLD), a chronic condition that can lead to cirrhosis, liver cancer and liver failure. [More]
Medical marijuana offers hope for kids with uncontrolled seizures

Medical marijuana offers hope for kids with uncontrolled seizures

Desperate for relief, parents are taking unusual steps to help children plagued with seizures. The relief, however, comes in a most unlikely form: marijuana. [More]
Abnormal breakage of chromosomes in white blood cells triggers aggressive form of ALL

Abnormal breakage of chromosomes in white blood cells triggers aggressive form of ALL

A research team led by St. Jude Children's Research Hospital scientists has discovered details of how the abnormal breakage and rearrangement of chromosomes in white blood cells triggers a particularly aggressive form of acute lymphoblastic leukemia (ALL). Such leukemias are cancers of white blood cells, in which genetic mutations trigger overproduction of immature cells, called lymphoblasts. [More]
Researchers show how antiretroviral therapy reduces HIV infection in female reproductive tract

Researchers show how antiretroviral therapy reduces HIV infection in female reproductive tract

For the first time, investigators in the Division of Infectious Diseases at the University of North Carolina School of Medicine have determined how antiretroviral therapy (ART) affects the way HIV disseminates and establishes infection in the female reproductive tract. [More]
Favourable safety, disease control for proton radiotherapy in paediatric medulloblastoma

Favourable safety, disease control for proton radiotherapy in paediatric medulloblastoma

Proton radiotherapy has an acceptable safety and disease control profile in paediatric medulloblastoma patients, according to research published in The Lancet Oncology. [More]
FDA clears Sangamo BioSciences' SB-318 IND application for treatment of MPS I

FDA clears Sangamo BioSciences' SB-318 IND application for treatment of MPS I

Sangamo BioSciences, Inc., the leader in therapeutic genome editing, announced that the U.S. Food and Drug Administration has cleared the Company's Investigational New Drug (IND) application for SB-318, a single treatment strategy intended to provide a life-long therapy for Mucopolysaccharidosis Type I (MPS I). [More]
Pivotal IDE clinical trial results for Cerapedics' i-FACTOR bone graft in ACDF procedures published in journal Spine

Pivotal IDE clinical trial results for Cerapedics' i-FACTOR bone graft in ACDF procedures published in journal Spine

Cerapedics, a privately-held orthobiologics company, announced today results from a pivotal FDA Investigational Device Exemption (IDE) clinical trial for i-FACTOR Peptide Enhanced Bone Graft in anterior cervical discectomy and fusion (ACDF) procedures have been electronically published in the peer-reviewed journal Spine. [More]
UTHealth researchers demonstrate new way to reduce preterm birth

UTHealth researchers demonstrate new way to reduce preterm birth

Using nanoparticles to engineer a special drug, a team of researchers from McGovern Medical School at The University of Texas Health Science Center at Houston has demonstrated in pre-clinical trials a new way to both reduce preterm birth and avoid the risks of medication in pregnancy to unborn babies. [More]
Positive pre-clinical study data of Lamellar Biomedical's Visco-ease published in Supportive Care Journal

Positive pre-clinical study data of Lamellar Biomedical's Visco-ease published in Supportive Care Journal

Lamellar Biomedical, a biotechnology company developing a range of patent-protected medical devices and pharmaceuticals, based on Lamellasome™ technology, is pleased to announce the publication of a paper in the Supportive Care in Cancer Journal. [More]
ONCOblot test shows promise in early detection of malignant mesothelioma

ONCOblot test shows promise in early detection of malignant mesothelioma

MorNuCo Laboratories of West Lafayette, Indiana, and their ONCOblot Test recently completed a retrospective clinical trial focusing on the early detection of malignant mesothelioma, with the exciting results that the ONCOblot test detected a molecular marker that is indicative of the presence of mesothelioma, 4-10 years in advance of clinical symptoms appearing. [More]
Using corticosteroids before late preterm delivery reduces respiratory complications in babies

Using corticosteroids before late preterm delivery reduces respiratory complications in babies

A multicenter clinical trial led by researchers at Columbia University Medical Center and NewYork-Presbyterian has found that the use of corticosteroids in mothers at risk for late preterm delivery significantly reduced the incidence of severe respiratory complications in their babies. [More]
Genetic profiling ‘feasible’ for paediatric cancer patients

Genetic profiling ‘feasible’ for paediatric cancer patients

Research published in JAMA Oncology demonstrates that tumour and germline molecular profiling is feasible in paediatric cancer patients and can have actionable findings. [More]
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