Cocaine dependence (or addiction) is physical and psychological dependency on the regular use of cocaine. It can result in severe physiological damage, psychosis, schizophrenia, lethargy, depression, or a potentially fatal overdose.
People addicted to cocaine make riskier decisions than healthy people after losing a potential reward, according to a study published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.
Identifying more effective treatment strategies tailored to individual responses for patients overcoming addiction to cocaine is the focus of a new clinical trial at McGovern Medical School at The University of Texas Health Science Center at Houston.
A DGIST research team led by Professor Su-Il In, who developed acupuncture needles combined with nanotechnology, was recognized as the world's first application of this technology.
A team of researchers led by Cardiff University has discovered a promising new drug treatment for cocaine addiction.
An international team led by scientists at The Scripps Research Institute has found strong evidence supporting a new strategy against drug addiction.
A new study from scientists at The Scripps Research Institute, funded by the National Institutes of Health's National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism, suggests that increased levels of a molecule in the brain, called hypocretin, may contribute to cocaine addiction.
Researchers at The University of Texas at Arlington are studying how fluctuating estrogen levels make females increasingly sensitive to the rewarding effects of cocaine and ultimately, vulnerable to cocaine addiction.
Scientists at Wake Forest Baptist Medical Center are one step closer to understanding what causes cocaine to be so addictive. The research findings are published in the current issue of the Journal of Neuroscience.
Addiction may be viewed as a disorder of reward learning. To date, addiction research has focused on the molecular adaptations through which memories of exposure to abused substances are encoded and maintained by nerve cells.
Scientists at USC have developed a new tool to modify brain activity and memory in targeted ways, without the help of any drugs or chemicals.
In the ongoing fight against drug addiction, researchers from the University of Pennsylvania's School of Nursing and Perelman School of Medicine have discovered a unique application for an FDA-approved drug currently used for obese patients and type 2 diabetics: treatment for cocaine dependence.
Combining the drug topiramate with psychological counseling curbed marijuana use among young smokers significantly more than did counseling alone, according to newly published results of a small randomized, controlled trial at Brown University. The results come with a caveat, however: many study volunteers couldn't tolerate the medicine's side effects.
University of Kentucky College of Pharmacy Professor Chang-Guo Zhan, along with fellow UK Professors Fang Zheng and Sharon Walsh, and Professor Mei-Chuan Ko from Wake Forest University, recently received $6 million in funding over five years to further develop a potential treatment for cocaine abuse.
A long-acting enzyme that rapidly and safely metabolizes cocaine in the blood stream is currently being investigated in animal models as a possible treatment for cocaine overdose.
Abstinence is the best way to avoid drug addiction. But in many societies, drug use is the norm, not the exception, especially by youth.
Researchers at the University at Buffalo have discovered a previously unknown neural pathway that can regulate changes made in the brain due to cocaine use, providing new insight into the molecular basis of cocaine addiction.
One of the major challenges of cocaine addiction is the high rate of relapse after periods of withdrawal and abstinence. But new research reveals that changes in our DNA during drug withdrawal may offer promising ways of developing more effective treatments for addiction.
The brain function of people addicted to cocaine is different from that of people who are not addicted and often linked to highly impulsive behavior, according to a new scientific study.
Researchers at the University of Copenhagen have gained new insight into the mechanism behind a protein dopamine transporter that could help in the development of future medical treatment against cocaine addiction.
Women are more sensitive to the effects of cocaine and more susceptible to cocaine abuse than men. Cocaine's ability to disrupt a woman's estrus cycle may explain the sex differences in cocaine addiction, and new evidence that caffeine may be neuroprotective and able to block cocaine's direct effects on the estrus cycle reveals novel treatment possibilities, according to an article published in Journal of Caffeine Research: The International Multidisciplinary Journal of Caffeine Science, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.