Colorectal News and Research

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Keryx KRX-0401 trial data against colorectal cancer, multiple myeloma to be presented at AACR

Keryx Biopharmaceuticals, Inc. today announced that two abstracts on KRX-0401 will be presented at the upcoming 102nd annual meeting of the American Association for Cancer Research to be held in Orlando, Florida, from April 2-6, 2011.

29 Mar 2011

Everist Genomics announces global launch of OncoDefender-CRC colorectal cancer assay

Everist Genomics today announced the worldwide commercial availability of its OncoDefender-CRC colorectal cancer assay, the first and only molecular prognostic test capable of accurately predicting the risk of recurrence of cancer in patients previously treated with surgical resection of a Stage I/II colon cancer tumor or Stage I rectal cancer tumor.

28 Mar 2011

FDA approves ipilimumab for metastatic melanoma treatment

The U.S. Food and Drug Administration announced today its approval of a new treatment for advanced melanoma, the deadliest and most difficult-to-treat form of skin cancer.

28 Mar 2011

APP voluntarily recalls Irinotecan Hydrochloride Injection for precautionary measure

APP Pharmaceuticals, Inc., announced today that it has issued a voluntary recall of five lots of Irinotecan Hydrochloride Injection, which is used for recurrent or progressive metastatic colorectal cancer.

28 Mar 2011

Clinical trial to determine whether Crestor can prevent new colon tumors after surgery

Christiana Care Health System's Helen F. Graham Cancer Center is leading a national clinical trial to determine if Crestor, a cholesterol-lowering drug, can prevent new colon tumors from forming after colon cancer surgery.

25 Mar 2011

Early diagnosis of colorectal cancer can minimize treatment side effects in survivors

Renato Lenzi, M.D., medical oncologist at The University of Texas MD Anderson Cancer Center and colon cancer survivor, knows only too well how important preventive methods are to beating colorectal cancer. After all, a routine colonoscopy saved his life.

24 Mar 2011

Jefferson begins patient recruitment for new clinical trail to prevent colon cancer

Thomas Jefferson University has started recruiting patients for a new National Cancer Institute-sponsored clinical trial to test whether the cholesterol-reducing drug rosuvastatin is effective in the prevention of recurrent colon cancer.

23 Mar 2011

Gastroenterologist directs new Crohn's and Colitis Program at UT Southwestern

Dorothy Stockstill was taking eight pills a day, and her severe abdominal pain and persistent diarrhea weren't improving. The Denton resident had seen multiple physicians throughout the Dallas area. Her attacks were so severe, she couldn't successfully travel from the front of a retail store to the restrooms in back.

23 Mar 2011

Researchers discover 'broad spectrum' cancer suppressor gene

Portuguese researchers have discovered a "broad spectrum" cancer suppressor gene - called LRP1B - which acts by removing proteins crucial for cancer development from the tumour environment. The fact that LRP1B does not act on the tumour itself (in this study thyroid tumours) but, instead, on molecules which are known to be important to many different cancers is what makes it so interesting.

21 Mar 2011

Research roundup: Successful medical homes; shortage of HIV doctors; boosting use of $4 generic drugs

Every Friday, Jennifer Evans compiles this selection of recently-released health policy studies and briefs.

19 Mar 2011

EMA CHMP adopts negative opinion for Amgen's Vectibix in treatment of wild-type KRAS metastatic colorectal cancer

Amgen has received notice that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a negative opinion for Amgen's application to extend the marketing authorization in Europe for Vectibix® (panitumumab) to include combination with chemotherapy for the treatment of patients with wild-type KRAS metastatic colorectal cancer (mCRC).

18 Mar 2011

Study: Stem cells may open door to new tools for colorectal cancer detection, treatment

Colorectal cancer cells trigger a set of genes similar to those found in intestinal stem cells, scientists at the Institute for Research in Biomedicine have found.

18 Mar 2011

Quest Diagnostics ColoVantage molecular colorectal cancer detection test receives New York State approval

Quest Diagnostics Incorporated, the world's leading cancer diagnostics company, today announced that its ColoVantage test has been approved by New York State's Department of Health for testing on samples of patients in the state. It is believed to be the first molecular colorectal cancer detection method that employs a venal blood specimen to be approved by the state.

From Quest Diagnostics 18 Mar 2011

PsiOxus commences MT-102 Phase II study for treatment of cancer- and age-related wasting

PsiOxus Therapeutics, Ltd. announced initiation of a Phase II study of MT-102, a small molecule therapeutic for the treatment of cancer- and age-related wasting. MT-102 is being developed to reverse the effects of cachexia, a wasting disease that accompanies cancer, heart failure, COPD, renal failure, cirrhosis and rheumatoid arthritis, and that is associated with significant morbidity and mortality.

17 Mar 2011

Scientist suggests breaking tangled mucus barrier can help treat cancer

Measuring the mechanical strength of cancer cell mucus layers provides clues about better ways to treat cancer, and also suggests why some cancer cells are more resistant to drugs than others, according to Kai-tak Wan, associate professor of engineering at Northeastern University, Boston, Mass.

17 Mar 2011

Human growth, height, size: Reasons to be small

Almost everybody these days thinks that it is best to be tall, meaning much taller than the average traditional height of Asian populations, and even taller than the current average height of populations in high-income countries. It is also often believed – though people might be shy to admit this – that tall people are intrinsically superior to short people. The expressions 'look up to' and 'look down on' are significant.

15 Mar 2011

Heavy drinking related to pancreatic cancer: Study

According to the latest research, heavy drinkers have an increased risk of dying from pancreatic cancer. The study has shown that non-smokers who have three or more drinks of hard liquor a day face a 36 percent higher risk of dying from pancreatic cancer, compared with non-drinkers. Smoking is a definite risk for pancreatic cancer. The report is published in the March 14 issue of the Archives of Internal Medicine.

15 Mar 2011

CLL patients receive Biothera's new combination therapy in Phase I/II clinical trial

Patients with earlier stage high-risk Chronic Lymphocytic Leukemia recently began receiving a new combination treatment in a Phase I/II clinical trial that researchers believe could result in a more effective therapy for this disease, Biothera announced today.

15 Mar 2011

Oxford Biomedica’s TroVax(R) TRIST Phase III study results to be published in Cancer Immunology, Immunotherapy

Oxford BioMedica plc, a leading gene therapy company, today announces that further analyses of the TroVax Renal Immunotherapy Survival Trial, a randomised, double-blind, placebo-controlled Phase III study, have been accepted for publication in Cancer Immunology, Immunotherapy, the official journal of the Association for Cancer Immunotherapy.

15 Mar 2011

Number of cancer survivors rise: CDC report

Latest figures show that many Americans are surviving cancer. In fact, 40 percent of cancer survivors have outlived their diagnoses by 10 years or more.

12 Mar 2011

Colorectal News and Research

Keryx KRX-0401 trial data against colorectal cancer, multiple myeloma to be presented at AACR

Everist Genomics announces global launch of OncoDefender-CRC colorectal cancer assay

FDA approves ipilimumab for metastatic melanoma treatment

APP voluntarily recalls Irinotecan Hydrochloride Injection for precautionary measure

Clinical trial to determine whether Crestor can prevent new colon tumors after surgery

Early diagnosis of colorectal cancer can minimize treatment side effects in survivors

Jefferson begins patient recruitment for new clinical trail to prevent colon cancer

Gastroenterologist directs new Crohn's and Colitis Program at UT Southwestern

Researchers discover 'broad spectrum' cancer suppressor gene

Research roundup: Successful medical homes; shortage of HIV doctors; boosting use of $4 generic drugs

EMA CHMP adopts negative opinion for Amgen's Vectibix in treatment of wild-type KRAS metastatic colorectal cancer

Study: Stem cells may open door to new tools for colorectal cancer detection, treatment

Quest Diagnostics ColoVantage molecular colorectal cancer detection test receives New York State approval

PsiOxus commences MT-102 Phase II study for treatment of cancer- and age-related wasting

Scientist suggests breaking tangled mucus barrier can help treat cancer

Human growth, height, size: Reasons to be small

Heavy drinking related to pancreatic cancer: Study

CLL patients receive Biothera's new combination therapy in Phase I/II clinical trial

Oxford Biomedica’s TroVax(R) TRIST Phase III study results to be published in Cancer Immunology, Immunotherapy

Number of cancer survivors rise: CDC report

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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