Colorectal News and Research

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Unintentional weight loss linked to increased risk of cancer diagnosis

Unintentional weight loss is associated with an increase in the risk of a cancer diagnosis within the coming year, according to a study from Dana-Farber Cancer Institute.

23 Jan 2024

Unraveling the logic of genes with Boolean network models

Over the last 20 years, researchers in biology and medicine have created Boolean network models to simulate complex systems and find solutions, including new treatments for colorectal cancer.

23 Jan 2024

Annexin-A1 targeted therapy beats several cancers

A new study published in Nature's cancer journal Oncogene highlights the effectiveness of MDX-124, the first therapeutic drug to target annexin-A1, a protein which is overexpressed in several cancer types and promotes tumour progression.

19 Jan 2024

Study shows promise of gene-based screening to fight colorectal cancer

Hereditary risk of colorectal cancer should be assessed in a more comprehensive way, shows a study led by researchers at the University of Helsinki, Finland.

17 Jan 2024

Novel blood test shows promise in detecting early-stage cancers with high accuracy

Researchers develop a novel plasma proteome-based test for early detection of multiple cancers, achieving high accuracy in identifying low-abundance protein biomarkers.

14 Jan 2024

Study explores intratumoral microbiota as a novel frontier in cancer research

Researchers review the role of intratumoral microbiota in cancer development, suggesting its potential in predicting and treating various cancers.

14 Jan 2024

Risk of gastrointestinal cancers translates to one in 12 people developing, and one in 16 people dying from, gastrointestinal cancers

Researchers estimated the lifetime risk of gastrointestinal cancer and associated mortality.

11 Jan 2024

Understanding how personalized nutrition and exercise programs can benefit cancer survivors

Researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have received funding to better understand how personalized nutrition and exercise programs can improve quality of life after cancer treatment.

10 Jan 2024

Research discovers fibronectin's role in BRAF-mutant thyroid cancer resistance

New research overseen by University of Colorado Cancer Center member Rebecca Schweppe, PhD, could lead to improved treatment for people with thyroid cancer characterized by a mutation in the BRAF gene -; a mutation also responsible for some types of melanoma, colorectal cancer, leukemia, lymphoma, and ovarian cancer.

10 Jan 2024

Study reveals mangos attenuates potential against colon cancer

The chemo-preventive potential of Mangiferin (MF) (mango).

10 Jan 2024

AI reveals hidden rules of cell neighborhoods in cancer

Researchers from Children's Hospital of Philadelphia have developed a new AI-powered algorithm to help understand how different cells organize themselves into particular tissues and communicate with one another.

8 Jan 2024

New AI tool spotlights hidden cancers for better diagnosis

A new artificial intelligence tool that interprets medical images with unprecedented clarity does so in a way that could allow time-strapped clinicians to dedicate their attention to critical aspects of disease diagnosis and image interpretation.

2 Jan 2024

Novel PET tracer accurately detects common cancer mutation for tailored treatment

A novel PET imaging tracer has been proven to safely and effectively detect a common cancer gene mutation that is an important molecular marker for tumor-targeted therapy.

2 Jan 2024

New study expands immunotherapy eligibility for colorectal and endometrial cancer patients

A new study shows thousands more patients diagnosed with colorectal and endometrial cancers could benefit from immunotherapy than are currently offered it.

29 Dec 2023

Insilico Medicine develops new AI-generated FGFR2/3 inhibitor for tissue-agnostic solid tumors

Insilico Medicine ("Insilico"), a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM8001, a novel molecule targeting FGFR2/3 for the treatment of tissue-agnostic solid tumors bringing the total number of PCCs nominated in 2023 to six.

28 Dec 2023

Next-gen sequencing identifies thousands of cancer patients missing out on immunotherapy

Brigham researchers' findings from next-generation sequencing suggest that revising current cancer care guidelines could allow approximately 6,000 more patients in the U.S. to benefit from immunotherapy treatment each year

28 Dec 2023

Simple mail trick doubles liver cancer screening rates for high-risk patients

Liver cancer screening among patients with cirrhosis almost doubled when they were mailed a signed order from their specialist, according to a new study from the Perelman School of Medicine at the University of Pennsylvania.

22 Dec 2023

“Forever chemicals” could contribute to cancer metastasis in living organisms

In a new study by researchers at the Yale School of Public Health, two "forever chemicals" spurred cancer cells in the lab to migrate to new positions, an indication that the chemicals could contribute to cancer metastasis in living organisms.

18 Dec 2023

Study points to the possibility of using cholesterol-lowering drugs to treat aggressive colorectal tumors

Hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend heavily on the ramped-up production of cholesterol, according to a preclinical study from researchers at Weill Cornell Medicine.

18 Dec 2023

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells.

15 Dec 2023

Colorectal News and Research

Unintentional weight loss linked to increased risk of cancer diagnosis

Unraveling the logic of genes with Boolean network models

Annexin-A1 targeted therapy beats several cancers

Study shows promise of gene-based screening to fight colorectal cancer

Novel blood test shows promise in detecting early-stage cancers with high accuracy

Study explores intratumoral microbiota as a novel frontier in cancer research

Risk of gastrointestinal cancers translates to one in 12 people developing, and one in 16 people dying from, gastrointestinal cancers

Understanding how personalized nutrition and exercise programs can benefit cancer survivors

Research discovers fibronectin's role in BRAF-mutant thyroid cancer resistance

Study reveals mangos attenuates potential against colon cancer

AI reveals hidden rules of cell neighborhoods in cancer

New AI tool spotlights hidden cancers for better diagnosis

Novel PET tracer accurately detects common cancer mutation for tailored treatment

New study expands immunotherapy eligibility for colorectal and endometrial cancer patients

Insilico Medicine develops new AI-generated FGFR2/3 inhibitor for tissue-agnostic solid tumors

Next-gen sequencing identifies thousands of cancer patients missing out on immunotherapy

Simple mail trick doubles liver cancer screening rates for high-risk patients

“Forever chemicals” could contribute to cancer metastasis in living organisms

Study points to the possibility of using cholesterol-lowering drugs to treat aggressive colorectal tumors

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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