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New research lays foundation for targeted therapies to inhibit NF-κB activation

A new paper by Dana-Farber Cancer Institute scientists lays the foundation for targeted therapies to inhibit activation of nuclear factor kappa B (NF-κB), a transcription factor that plays a role in various autoimmune and inflammatory diseases and cancers.

25 Apr 2024

CN Bio raises $21 million USD in first close of Series B investment round

Bayland Capital and founding shareholder, CN Innovations Holdings Ltd, to invest $10 M and $5.5 M, respectively. Investment will expand product development and scaling of the organization to meet increased demand for Organ-on-a-Chip (OOC) solutions.

23 Apr 2024

Natural obesity fighters: How coffee, tea, and cocoa combat weight gain

A review in Current Research in Food Science explores how bioactive compounds in coffee, tea, and cocoa combat obesity by inhibiting white adipogenesis and promoting brown adipogenesis and lipolysis.

22 Apr 2024

Engineered peptides show promise in cancer immunotherapy

In a new study published today in Nature Biomedical Engineering, researchers at The University of Texas MD Anderson Cancer Center have designed a new method for developing immunotherapy drugs using engineered peptides to elicit a natural immune response inside the body.

22 Apr 2024

Study reveals key protein's role in balancing immune response to viral infections

Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells.

18 Apr 2024

Piquin chili's health benefits spotlighted due to high antioxidant content

Researchers highlighted the nutraceutical potential of piquin chili, focusing on its rich content of capsaicinoids, carotenoids, and flavonoids, which contribute to its antioxidant properties.

17 Apr 2024

Study reveals novel approach to promote efficient uptake of ASOs into cancer cells

Antisense oligonucleotides (ASOs) are next-generation drugs that can treat disease by blocking the transfer of harmful messages from our genes.

16 Apr 2024

Proteasomes: Expanding roles beyond cellular waste management

The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts.

13 Apr 2024

Insilico Medicine's AI-driven approach yields promising PTPN2/N1 inhibitor for cancer immunotherapy

In recent years, cancer immunotherapy, exemplified by PD-1 and its ligand PD-L1 blockade, has made remarkable advances.

13 Apr 2024

Metrion Biosciences enhances High Throughput Screening services with access to Enamine compound libraries

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From Metrion Biosciences Limited 11 Apr 2024

Edetate disodium-based chelation ineffective for heart attack patients with diabetes

People with diabetes who had suffered a heart attack derived no clinical benefit from edetate disodium-based chelation, a therapy that draws lead and other toxic metals linked to increased risk of heart disease and stroke out of the body, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

New method to evaluate enzymes opens path to ferroptosis-targeting cancer drugs

New research could pave the way to develop cancer drugs targeting an enzyme that inhibits ferroptosis, a type of cell death.

5 Apr 2024

Understanding the mechanisms behind cystic fibrosis infections

Cystic fibrosis is a genetic disease that causes serious and sometimes fatal respiratory and digestive disorders.

4 Apr 2024

Newly discovered cause for asthma sparks hope for treatment

Scientists at King's College London have discovered a new cause for asthma that sparks hope for treatment that could prevent the life-threatening disease.

4 Apr 2024

Concordia researchers link vaping additives to lung damage

The health risks associated with consumption of tobacco and cannabis products are well-established by now. Much less understood are the risks associated with vaping, particularly flavoured products popular with young adults.

4 Apr 2024

Wastewater study sheds light on tracking cannabis use challenges

Researchers explore wastewater-based surveillance (WBS) as a tool to monitor cannabis use, identifying analytical challenges and the need for more precise methodologies.

3 Apr 2024

New study to test novel psychedelic compound as potential treatment for alcohol use disorder

Modern mental health company Clerkenwell Health announced today that it is working with clinical-stage biotechnology company Beckley Psytech on a Phase IIa study investigating whether a novel psychedelic compound, combined with psychological support, could be an effective treatment for alcohol use disorder (AUD).

29 Mar 2024