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Einstein researcher receives $7.5 million NIH grant to study genetics of congenital heart disease

Einstein researcher receives $7.5 million NIH grant to study genetics of congenital heart disease

The National Institutes of Health has awarded Bernice Morrow, Ph.D., at Albert Einstein College of Medicine and collaborators at the Children's Hospital of Philadelphia a five-year, $7.5 million grant to study the genetics of congenital heart abnormalities. [More]
Researchers create temporal and spatial atlas that plots development of mouse heart

Researchers create temporal and spatial atlas that plots development of mouse heart

It's not simple, making a heart. In the womb, the organ begins as a tube, sprouts bead-like lumps, folds in on itself and eventually morphs into the more familiar-looking four-chambered structure. [More]
Women with CHD more likely to have safe and healthy pregnancies, study finds

Women with CHD more likely to have safe and healthy pregnancies, study finds

Congenital heart disease (CHD), a group of abnormalities in the heart that develop before birth - including holes in the heart, leaky or narrow valves, and incomplete or missing parts - affects nearly one percent of all babies born in the United States each year - upwards of 40,000 infants. [More]
CRF to release new international journal focusing on diagnosis, treatment of structural heart disease

CRF to release new international journal focusing on diagnosis, treatment of structural heart disease

The Cardiovascular Research Foundation announced that it will launch a new international journal focusing on the diagnosis and treatment of structural heart disease and the importance of the heart team in managing these disorders. [More]
Diamond publishes milestone paper that reveals discovery of genetic triggers behind birth defects

Diamond publishes milestone paper that reveals discovery of genetic triggers behind birth defects

Researchers at the UK's national synchrotron facility, Diamond Light Source, have just published the 5000th scientific paper using data from the facility. This milestone marks a significant step for the synchrotron that is used by over 8,000 scientists each year. [More]
NCDR provides data to study appropriate use of oral anticoagulant therapy

NCDR provides data to study appropriate use of oral anticoagulant therapy

The American College of Cardiology's National Cardiovascular Data Registry was the source of data for research published throughout 2016, including a study examining if atrial fibrillation patients are being prescribed oral anticoagulants, how appropriate use criteria correlates to angioplasty rates and the variation among racial groups for revascularization procedures. [More]
Study finds mutations in three new genes can cause rare syndromic CHD disorders

Study finds mutations in three new genes can cause rare syndromic CHD disorders

Researchers at The University of Nottingham have been involved in one of the largest international studies of congenital heart disease, which has discovered gene mutations linked to three new rare congenital heart disorders (CHD). [More]
Children born with CHD more likely to develop type 2 diabetes in adulthood

Children born with CHD more likely to develop type 2 diabetes in adulthood

Children born with heart disease have an increased risk of developing type 2 diabetes after age 30, according to a new study. [More]
Study identifies genetic mutations responsible for development of cardiac hypertrophy in adults

Study identifies genetic mutations responsible for development of cardiac hypertrophy in adults

Investigators at Beth Israel Deaconess Medical Center have identified a developmental cause of adult-onset cardiac hypertrophy, a dangerous thickening of the heart muscle that can lead to heart failure and death. [More]
Innovative website reveals NHS children's heart surgery statistics to decision makers and parents

Innovative website reveals NHS children's heart surgery statistics to decision makers and parents

Researchers are calling for the end to an era of confusion and alarm about children's heart surgery statistics by launching an innovative communication tool that will help people make sense of published survival data about children's heart surgery in the UK and Ireland. [More]
New blood test could help predict severity of pulmonary arterial hypertension

New blood test could help predict severity of pulmonary arterial hypertension

Johns Hopkins Medicine researchers report that rising blood levels of a protein called hematoma derived growth factor (HDGF) are linked to the increasing severity of pulmonary arterial hypertension, a form of damaging high blood pressure in the lungs. [More]
Scientists aim to heal failing heart with the body’s own cells

Scientists aim to heal failing heart with the body’s own cells

Babies born with heart defects live longer than ever thanks to advances in the diagnosis and treatment of congenital heart disease. Yet, despite substantial progress, many continue to face bleak odds, lifelong medication, multiple surgeries and progressive heart failure, often requiring a transplant. [More]
First-ever clinical trial of bioabsorbable cardiovascular device in children shows promise

First-ever clinical trial of bioabsorbable cardiovascular device in children shows promise

Current cardiovascular valve or blood vessel implants are generally associated with a number of complications, have limited efficacy over time, and may necessitate repeated interventions over a patient's lifetime, especially when implanted in a young child. [More]
Japanese surgeons develop new technique to relieve airway obstruction in children

Japanese surgeons develop new technique to relieve airway obstruction in children

Several pediatric medical conditions, such as congenital heart disease, vascular compression, and congenital softening of the cartilage lining the trachea or bronchi, can compromise the airway and cause breathing difficulty. [More]
Clinicians describe placement of first implantable hemodynamic monitor in single ventricle Fontan anatomy

Clinicians describe placement of first implantable hemodynamic monitor in single ventricle Fontan anatomy

While the Fontan procedure has improved the short- and mid-term outcomes for patients born with single ventricle anatomy, long-term complications of Fontan circulation include heart failure. These complications are thought to be secondary to elevated central venous pressure, chronic venous congestion and low cardiac output. [More]
Acid suppression drugs frequently prescribed for high-risk newborns, study shows

Acid suppression drugs frequently prescribed for high-risk newborns, study shows

Since 2006, several published studies have associated the use of some acid suppression medications in hospitalized high-risk babies with infections, necrotizing enterocolitis and increased risk of death. Those medications - histamine-2 receptor antagonists, such as ranitidine (Zantac and others), and proton pump inhibitors, such as esomeprazole (Nexium and others) - were originally approved by the U.S. Food and Drug Administration for use in adults and older children. [More]
Pediatric researchers develop minimally invasive techniques to treat plastic bronchitis

Pediatric researchers develop minimally invasive techniques to treat plastic bronchitis

Pediatric researchers have devised an innovative, safe and minimally invasive procedure that helps relieve rare but potentially life-threatening airway blockages occurring in children who had surgery for congenital heart defects. [More]
Boston Children's, Edwards Lifesciences launch new prosthetic heart valve study for congenital heart defect

Boston Children's, Edwards Lifesciences launch new prosthetic heart valve study for congenital heart defect

Surgeons in the Heart Center at Boston Children's Hospital have partnered with Edwards Lifesciences to launch a clinical study of a new prosthetic heart valve for patients born with a congenital heart defect. [More]
Anti-anxiety drug reduces autistic features in Jacobsen syndrome mice

Anti-anxiety drug reduces autistic features in Jacobsen syndrome mice

About half of children born with Jacobsen syndrome, a rare inherited disease, experience social and behavioral issues consistent with autism spectrum disorders. Researchers at University of California, San Diego School of Medicine and collaborators developed a mouse model of the disease that also exhibits autism-like social behaviors and used it to unravel the molecular mechanism that connects the genetic defects inherited in Jacobsen syndrome to effects on brain function. [More]
Adults living with congenital heart disease may have higher risk of PTSD

Adults living with congenital heart disease may have higher risk of PTSD

Adults living with congenital heart disease (CHD) may have a significantly higher risk of post-traumatic stress disorder (PTSD) than people in the general population. [More]
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