Coronary Artery Bypass Graft News and Research

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FDA approves Effient (prasugrel) for heart attack in angioplasty patients

The U.S. Food and Drug Administration has approved the blood-thinning drug Effient tablets (prasugrel) to reduce the risk of blood clots from forming in patients who undergo angioplasty, a common procedure to unblock a clogged coronary artery.

12 Jul 2009

Health reformers shy from proposals that would limit treatment options

In a story headlined 'In Retooled Health-Care System, Who Will Say No?' the Washington Post reports: "Although Obama and his advisers have held up providers' spending patterns as the crux of the crisis, proposals in Washington go only so far in addressing the thorniest questions about who gets what care."

8 Jul 2009

Diabetes with coronary disease: A moving target amid evolving therapies

In an editorial in the current issue of the New England Journal of Medicine (NEJM), William E. Boden, M.D., professor of medicine and preventive medicine at the University at Buffalo, recommends that the results of the BARI-2D Trial published in that edition must be interpreted with "considerable caution."

8 Jun 2009

Schering-Plough starts patient enrollment in phase 3 trial for Acadesine

Schering-Plough Corporation today announced the start of patient enrollment in RED-CABG, the Phase 3 Trial for acadesine, an investigational, potentially first-in-class adenosine regulating agent (ARA). Acadesine was licensed from PeriCor Therapeutics, Inc., a privately held specialty biopharmaceutical company.

12 May 2009

Two non-pharmacological interventions reduce depression after heart surgery

Two non-pharmacological interventions-cognitive behavior therapy and supportive stress management-appear more effective than usual care for treating depression after coronary artery bypass surgery, according to a report in the April issue of Archives of General Psychiatry.

6 Apr 2009

Drug-coated stents lower risk of heart attack and death

Heart disease patients 65 and older who receive stents coated with medicine to prevent blockages are more likely to survive and less likely to suffer a heart attack than people fitted with stents not coated with medication, according to a new study supported by HHS' Agency for Healthcare Research and Quality and the American College of Cardiology's National Cardiovascular Data Registry.

30 Mar 2009

Clinical effectiveness of coronary stents in the elderly

29 Mar 2009

Heart bypass surgery better than angioplasty for certain patients

After three years working with investigators from 10 different clinical trials around the world from Brazil to London to Pittsburgh, Stanford University School of Medicine researchers have pooled enough individual patient data to compare the effectiveness of coronary artery bypass surgery with the less-invasive angioplasty procedure on specific groups of patients for the first time.

20 Mar 2009

SYNTAX defines borders between CABG and PCI with TAXUS drug-eluting stents

Coronary artery bypass grafting (CABG) should remain the "standard of care" for patients with complex coronary artery disease, concludes the SYNTAX study, published in the New England Journal of Medicine (online February 18, 2009, Print edition March 5).

23 Feb 2009

Statins can stimulate cardiac muscle cell regeneration, improve heart function

Statins, used widely to treat elevated cholesterol, have been shown to prevent progression of coronary narrowing and to have other beneficial effects on the heart, such as reducing inflammation, that are independent of cholesterol.

23 Feb 2009

High-tech hospitals see fewer complications, lower costs

Texas hospitals using health information technologies had fewer complications, lower mortality rates and lower costs, a UT Southwestern Medical Center researcher has found.

3 Feb 2009

Easing regulations does not mean lower quality of cardiac care

States that dropped regulations overseeing the performance of two common heart procedures showed no increase in death rates, according to researchers at Baylor College of Medicine (BCM), Rice University and Duke University Medical Center.

29 Jan 2009

Health IT associated with better outcomes, lower costs

Patients at Texas hospitals that have automated some aspects of their health information systems appear to have fewer complications, lower death rates and reduced costs, according to a report in the January 26 issue of Archives of Internal Medicine , one of the JAMA/Archives journals.

27 Jan 2009

Timing is everything for some heart attack patients

There is strong evidence that getting to the hospital quickly during a heart attack is critical, since early treatment saves both lives and heart muscle. And if the responsible coronary artery is completely blocked, it should be opened as soon as possible.

11 Nov 2008

Delaying elective coronary artery bypass graft surgery: post-operative death risks

Delaying elective coronary artery bypass graft (CABG) surgery may be a significant risk factor for post-operative death. Research published today in the open access journal BMC Health Services Research reveals that when patients received timely surgery, the risk of death was reduced by a third.

21 Sep 2008

Researchers say heart bypass a better option than drug-eluting stents

Major clinical research has found that for many patients with clogged arteries, bypass surgery is a better option than drug-eluting stents.

2 Sep 2008

Who needs cardiac surgery?

Throughout the developed world, cardiac surgery faces increasing challenges from percutaneous intervention, currently with revascularisation, but potentially soon for valve replacement as well. The spectacular growth of PCI in the UK over the last five years is typical for many developed countries.

31 Aug 2008

Disruption of blood sugar levels after heart surgery is common

A study reveals today that inadequate blood sugar control in patients having heart surgery is associated with a four fold increase in post-surgery death and major complications - and that the blood sugar disturbances occur in patients with and without diabetes.

7 Jul 2008

Drug-releasing coronary artery stent use linked with decrease in procedures to unblock coronary arteries

The widespread adoption of the use of drug-releasing coronary artery stents into routine practice is associated with a decrease in the need for repeat procedures to unblock coronary arteries and also do not appear to increase the risk of death, compared to bare-metal stents, according to a study in the June 25 issue of JAMA, the Journal of the American Medical Association

24 Jun 2008

Nearly one in five patients experiences chest pain one year after having a heart attack

One of the main goals of in-hospital treatment and outpatient care after heart attack is to relieve angina (or episodic chest pain), according to background information in the article. The prevalence and treatment of chest pain one year after heart attack are largely unknown.

24 Jun 2008