Corticosteroid News and Research

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Corticosteroids are any steroid hormones made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias.

COVID-19 pandemic highlights the risk of using systemic corticosteroids

Healthcare workers in tropical and sub-tropical settings where strongyloidiasis is prevalent or caring for patients who have travelled to such areas, need to maintain a high level of awareness about the use of corticosteroids, including when this class of anti-inflammatories is given to patients suspected of infection with SARS-CoV-2.

17 Dec 2020

Azithromycin trial fails to provide evidence of benefit in COVID-19

Early on in the COVID-19 pandemic, azithromycin was regarded as being a potentially highly effective drug against the virus that causes it, SARS-CoV-2.

16 Dec 2020

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

A potentially valuable new study discusses the role of lipids in the hyper-inflammatory phenomena that take place within the lungs of patients with severe or critical COVID-19. Involving a large variety of specialized lipids with biological activity, this process includes the generation and release of pro and anti-inflammatory lipids.

8 Dec 2020

Could beta-blockers be a potential treatment for COVID-19?

News-Medical spoke to researchers about their latest research into beta-blockers, and how they could potentially be used to treat COVID-19.

27 Nov 2020

Dexamethasone use could reduce immune checkpoint inhibitor efficacy in glioblastoma patients

Bottom Line: Among patients with glioblastoma receiving an immune checkpoint inhibitor, those who received the corticosteroid dexamethasone at baseline for cerebral edema had significantly worse overall survival.

25 Nov 2020

First intratumoral injection approved by FDA for treating non-metastatic mast cell tumors in dogs

Today, the U.S. Food and Drug Administration approved Stelfonta (tigilanol tiglate injection) to treat dogs with non-metastatic, skin-based (cutaneous) mast cell tumors (MCTs).

17 Nov 2020

Corticosteroids can help in survival of elderly patients with severe COVID-19

A new study group based in France have looked at the rates of survival among elderly patients with COVID-19 who were administered with corticosteroids.

16 Nov 2020

Care pathways for pregnant women with COVID‐19

A recent review published in the journal Global Challenges in October 2020, sums up what is currently known about the treatment of COVID-19 during pregnancy and offers recommendations for how healthcare professions might better manage pregnant COVID-19 patients in the future.

16 Nov 2020

New procedure offers lasting pain relief for patients with osteoarthritis

A novel outpatient procedure offers lasting pain relief for patients suffering from moderate to severe arthritis in their hip and shoulder joints, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA).

16 Nov 2020

Lupus patients receiving prophylactic therapy are at high risk for adverse reactions

New research shows that adults with systemic lupus erythematosus, who receive trimethoprim-sulfamethoxazole (TMP-SMX), a prophylactic therapy to help prevent pneumocystis pneumonia, are at high risk for adverse reactions to the drug, particularly if they are also positive for anti-Smith (anti-Sm) antibodies.

6 Nov 2020

Corticosteroid injections for knee OA do not speed up the progression of disease

New research shows that corticosteroid injections for knee OA treatment do not hasten a patient's progression to a total knee replacement when compared with hyaluronic acid injections.

6 Nov 2020

High-impact clinical trial results could improve kidney-related medical care

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25.

23 Oct 2020

Dexamethasone drug may not benefit COVID-19 patients with diabetes or low albumin levels

A new discovery about how the body transports dexamethasone, a drug that can increase the survival chances of patients with severe COVID-19, suggests diabetes and other factors may reduce its potentially lifesaving effectiveness.

23 Oct 2020

Conflicting evidence on potential benefit, negative outcomes of hip and knee steroid injections

Osteoarthritis of the hip and knee is among the most common joint disorders. A frequently performed treatment for osteoarthritis and other joint related pain syndromes are IACS, yet there is conflicting evidence on their potential benefit and possible negative outcomes following such injections.

20 Oct 2020