CpG News and Research

RSS

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Researchers across Europe have delved into the DNA methylation patterns in CD4+ T-cells of psoriasis and psoriatic arthritis (PsA) patients, unveiling potential new biomarkers for these conditions. Their study suggests that these unique profiles could serve as both diagnostic and prognostic tools, although further validation is needed for real-world clinical application.

10 Sep 2023

Promising new cervical cancer test fills in the gap missed by Pap tests

Researchers assessed a novel human papillomavirus (HPV) and host deoxyribonucleic acid (DNA) methylation score for adenocarcinoma in-situ (AIS) and cervical adenocarcinoma (ADC) screening.

8 Sep 2023

Maternal obesity linked to childhood weight issues through DNA changes

Boston Birth Cohort study finds that maternal pre-pregnancy obesity alters newborn DNA methylation, potentially increasing the risk of obesity in the child. The research targets high-risk U.S. demographics and could guide future interventions for childhood obesity.

27 Aug 2023

The interplay between the microbiota, the epigenome, and nutrition among obese adults during behavioral weight reduction

Study evaluated associations between gut microbiome (MB), deoxyribonucleic acid (DNA) methylation (DNAme), and nutrition.

21 Aug 2023

Early lung cancer detection with a machine learning model based on imaging, clinical, and DNA methylation biomarkers

Researchers discuss the development and validation of a combined model for the early diagnosis of lung cancer.

15 Aug 2023

Epigenetic drug-sensitive biomarkers for cancer

Researchers perform an epigenome-wide multi-omic high-throughput screen to identify actionable epigenetic drug-sensitive biomarkers.

15 Aug 2023

Novel multi-epitope subunit vaccine induces robust immune response against Epstein-Barr virus

Scientists have developed a lymph node-targeted multi-epitope subunit vaccine that induces strong humoral and cellular immune responses against EBV in mice.

14 Aug 2023

Exploring DNA methylation biomarkers of multiple sclerosis

Researchers identify cell-specific DNA methylation signatures associated with MS.

14 Aug 2023

Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load

In a recent study, researchers working at Ohio State University in the United States of America (USA) developed an intranasal subunit vaccine.

2 Aug 2023

Can epigenetic changes explain the strong link between age and cancer?

Researchers reported the link between aging, cancer, and epigenomic changes.

26 Jul 2023

Advancing vaccine adjuvants: exploring cutting-edge platforms for improved immunization

A group of authors summarized adjuvant mechanisms, characteristics, and applications, seeking to overcome current vaccine limitations.

21 Jul 2023

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Researchers develop and characterize a highly specific EpiEditing system using catalytically inactivated catalytically inactivated Cas9.

17 Jul 2023

Albumedix and Valneva expand collaboration to include newly approved inactivated COVID-19 vaccine

Albumedix Ltd., a recognized global leader in Recombinant Human Albumin (rHA), specializing in the enablement of advanced therapies and biopharmaceuticals, today announces the expansion of its existing collaboration with Valneva SE, a specialty vaccine company focused on prevention of infectious diseases with significant unmet medical need.

From Albumedix Ltd. 29 Jun 2023

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Melatonin, a hormone derived from the pineal gland, has diverse effects on cellular processes. This review explores its potential role as an epigenetic regulator, particularly in modulating DNA methylation, and suggests its use in combination therapy as a novel anticancer strategy.

30 May 2023

New tool launched to make ESMO Clinical Practice Guidelines easier to use in routine clinical practice

ESMO, the leading professional organization for medical oncology, today announced the launch of a new tool designed to make the renowned ESMO Clinical Practice Guidelines (CPGs) easier to use in oncologists' routine clinical practice and support optimal decision-making in a rapidly evolving medical field.

10 May 2023

CpG News and Research

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Promising new cervical cancer test fills in the gap missed by Pap tests

Maternal obesity linked to childhood weight issues through DNA changes

The interplay between the microbiota, the epigenome, and nutrition among obese adults during behavioral weight reduction

Early lung cancer detection with a machine learning model based on imaging, clinical, and DNA methylation biomarkers

Epigenetic drug-sensitive biomarkers for cancer

Novel multi-epitope subunit vaccine induces robust immune response against Epstein-Barr virus

Exploring DNA methylation biomarkers of multiple sclerosis

Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load

Can epigenetic changes explain the strong link between age and cancer?

Advancing vaccine adjuvants: exploring cutting-edge platforms for improved immunization

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Albumedix and Valneva expand collaboration to include newly approved inactivated COVID-19 vaccine

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

New tool launched to make ESMO Clinical Practice Guidelines easier to use in routine clinical practice

A novel species of dependoparvovirus has been identified in monk parakeets in Madrid

Age-induced methylation changes in the sperm epigenome contribute to offspring's medical problems

Machine learning applications for the diagnosis, treatment and prognosis of cancer

How maternal obesity and gestational diabetes can impact DNA methylation in infants

Maternal obesity associated with adverse metabolic health outcomes in childhood

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News