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Sodium excretion linked to CVD risk in chronic kidney disease

Sodium excretion linked to CVD risk in chronic kidney disease

High levels of sodium excretion are associated with a significantly increased risk of cardiovascular disease in patients with chronic kidney disease (CKD), US study findings indicate. [More]
Bare metal stents no longer advisable for high bleeding risk ACS patients

Bare metal stents no longer advisable for high bleeding risk ACS patients

A polymer-free, drug-coated stent gives markedly better outcomes than a bare metal stent in patients with acute coronary syndromes and risk factors for bleeding, report researchers. [More]
Phase I study of triple drug combination shows promise in multiple myeloma patients

Phase I study of triple drug combination shows promise in multiple myeloma patients

PharmaMar announces the positive results from a Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed and/or refractory multiple myeloma. [More]
New AVERT system can reduce radiographic dye volume in patients at risk of AKI

New AVERT system can reduce radiographic dye volume in patients at risk of AKI

In the largest study of its kind, a new device has been found to significantly reduce the volume of radiographic dye without decreasing image quality in patients who are at risk of developing acute kidney injury (AKI) after undergoing a coronary angiography or percutaneous coronary intervention (PCI). [More]
MR may detect earliest Alzheimer's brain changes

MR may detect earliest Alzheimer's brain changes

Levels of the brain metabolite and neuroinflammation marker myo-inositol are elevated in asymptomatic patients with abnormal Alzheimer's disease (AD) biomarkers, say researchers. As repo ... [More]
Person's age, mobility could be powerful predictors of survival than certain biomarkers

Person's age, mobility could be powerful predictors of survival than certain biomarkers

Advances in technology allow scientists to measure intricate details about the human body that greatly enhance understanding of health, disease and aging. [More]
Investigational drug provides no improved protection to patients with contrast-induced acute kidney injury

Investigational drug provides no improved protection to patients with contrast-induced acute kidney injury

Patients treated with CMX-2043--an investigational drug that has previously shown some ability to protect heart muscle from damage during stenting--saw no improved protection in their kidneys compared to placebo, according to research presented at the American College of Cardiology's 65th Annual Scientific Session. [More]
MALDI tissue imaging spots early renal lipid changes in acute kidney injury

MALDI tissue imaging spots early renal lipid changes in acute kidney injury

University of Alabama at Birmingham researchers have made a microscopic snapshot of the early renal lipid changes in acute kidney injury, using the laser-scanning method called MALDI tissue imaging to localize the changes. [More]
Real-world data confirm TDF efficacy for HBV

Real-world data confirm TDF efficacy for HBV

Treatment with tenofovir disoproxil fumarate elicits sustained virological responses and exhibits a favourable safety profile in a diverse population of patients with chronic hepatitis B virus infection, shows a French routine clinical practice study. [More]
FDA approves Allergan's sNDA to update label for DALVANCE (dalbavancin) for injection

FDA approves Allergan's sNDA to update label for DALVANCE (dalbavancin) for injection

Allergan plc, a leading global pharmaceutical company, today announced the U.S. Food and Drug Administration has approved the company's supplemental new drug application (sNDA) to update the label for DALVANCE (dalbavancin) for injection. [More]
Dynamic light scattering technique may help detect people at risk of cataracts and presbyopia

Dynamic light scattering technique may help detect people at risk of cataracts and presbyopia

As we age, proteins in the lenses of our eyes start misbehaving: They unfold and congregate in clusters that block, scatter and distort light as it passes through the lens. A cloudy area, or cataract, forms. In a new study, scientists found that throughout our lifetime, levels of a key protein decline, and may be an early warning sign of a developing cataract. [More]
Zurampic (lesinurad) approved to treat high levels of hyperuricemia associated with gout

Zurampic (lesinurad) approved to treat high levels of hyperuricemia associated with gout

The U.S. Food and Drug Administration today approved Zurampic (lesinurad) to treat high levels of uric acid in the blood (hyperuricemia) associated with gout, when used in combination with a xanthine oxidase inhibitor (XOI), a type of drug approved to reduce the production of uric acid in the body. [More]
Mayo Clinic researchers report national trend toward overtesting HbA1C levels in diabetes patients

Mayo Clinic researchers report national trend toward overtesting HbA1C levels in diabetes patients

In a study released online today in The BMJ, researchers from Mayo Clinic report a national trend toward overtesting glycated hemoglobin (HbA1C) levels in adult patients with Type 2 diabetes. [More]
New article reveals link between poor kidney function, worse outcomes after heart surgery

New article reveals link between poor kidney function, worse outcomes after heart surgery

Poor kidney function prior to heart surgery can lead to worse outcomes, higher surgical costs, and a longer hospital stay, according to an article posted online today by The Annals of Thoracic Surgery. [More]
Personalised peptide vaccination promising in bladder cancer

Personalised peptide vaccination promising in bladder cancer

Metastatic bladder cancer patients who have progressed on first-line platinum-based chemotherapy could derive survival benefits from personalised peptide vaccination, according to phase II trial results. [More]
U.S. adults who use smokeless tobacco products have higher levels of nicotine, carcinogen

U.S. adults who use smokeless tobacco products have higher levels of nicotine, carcinogen

U.S. adults who used only smokeless tobacco products had higher levels of biomarkers of exposure to nicotine and a cancer-causing toxicant -- the tobacco-specific nitrosamine NNK -- compared with those who used only cigarettes [More]
White coat hypertension, masked hypertension increase cardiovascular events over the years

White coat hypertension, masked hypertension increase cardiovascular events over the years

Patients whose blood pressures spikes in the doctor's office but not at home, and patients whose blood pressure spikes at home but not in the doctor's office, suffer more heart attacks, heart failure, and strokes than patients with normal blood pressures in both settings, UT Southwestern Medical Center researchers have found. [More]
Presence of tophi in people with gout can increase risk of developing cardiovascular disease

Presence of tophi in people with gout can increase risk of developing cardiovascular disease

The presence of tophi - crystal deposits of uric acid found on the surface of the joints or in the skin and cartilage - in people with gout can increase their risk of developing cardiovascular disease, according to research presented this week at the American College of Rheumatology Annual Meeting in San Francisco. [More]
Circulating protein predicts risk of chronic kidney disease

Circulating protein predicts risk of chronic kidney disease

Make room, cholesterol. A new disease marker is entering the medical lexicon: suPAR, or soluble urokinase-type plasminogen activator receptor. [More]
Allergan's anti-infective portfolio to be highlighted at IDWeek 2015

Allergan's anti-infective portfolio to be highlighted at IDWeek 2015

Allergan plc today announced that its infectious disease portfolio will be featured in 13 abstracts highlighting data at IDWeek 2015, which takes place from October 7-11, 2015, in San Diego. [More]
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