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Long-term hormone treatment may negatively affect kidneys in postmenopausal women

Long-term hormone treatment may negatively affect kidneys in postmenopausal women

Long-term estrogen treatment after menopause may increase the risk of new kidney damage and negatively affect women with abnormal kidney function. [More]
Study shows physicians in pediatric ICUs do not use newest guidelines to diagnose AKI in children

Study shows physicians in pediatric ICUs do not use newest guidelines to diagnose AKI in children

A study by University at Buffalo researchers has shown that physicians in pediatric intensive care units are not using the newest guidelines to diagnose acute kidney injury (AKI) in critically ill children, a practice that could affect their patients' long-term health. [More]
Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models

Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models

Results of preclinical studies by investigators at the Medical University of South Carolina reported in the August 2016 issue of Arthritis & Rheumatology demonstrate for the first time that including novel biomarkers in lupus nephritis (LN) prognostic models significantly increases their power to predict therapeutic efficacy. [More]
Using biomarkers to diagnose sepsis: an interview with Jordi Trafi

Using biomarkers to diagnose sepsis: an interview with Jordi Trafi

Sepsis, according to the new clinical definition of sepsis, is organ dysfunction caused by the body’s dysregulated response to an infection. Sepsis is common, with about 20 million patients/year in the developed world. It can escalate to septic shock, which is a life-threatening condition with a mortality rate of about 40%. In fact, about every second someone in the world dies of sepsis. [More]
Radiometer announces sponsorship for World Sepsis Day 2016

Radiometer announces sponsorship for World Sepsis Day 2016

Radiometer is proud to announce that it is sponsoring this year’s World Sepsis Day on the 13th September, continuing its commitment to the fight against this life-threatening medical condition. [More]
Free online World Sepsis Congress sponsored by Radiometer

Free online World Sepsis Congress sponsored by Radiometer

Radiometer is proud to announce that it is sponsoring the 1st World Sepsis Congress, from the 8th to the 9th of September 2016. Organized by the Global Sepsis Alliance, this free online event will give participants the chance to hear experts from around the world discuss the challenges and opportunities in the battle against this life-threatening illness. [More]
European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year. [More]
iMDsoft launches new mobile e-obs solution for early detection of sepsis and AKI

iMDsoft launches new mobile e-obs solution for early detection of sepsis and AKI

iMDsoft announced that they will be featuring new and advanced tools for detecting patient deterioration at Patient Safety Congress in Manchester, 5 - 6 July 2016. [More]
Empagliflozin offers long-term renal protection in Type 2 diabetes

Empagliflozin offers long-term renal protection in Type 2 diabetes

The sodium-glucose cotransporter 2 inhibitor empagliflozin slows renal progression and averts clinical events, shows further analysis of the EMPA-REG OUTCOME trial. [More]
Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients

Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients

Researchers at the University of Cincinnati College of Medicine have found that adding increasing doses of an approved Type 2 diabetes drug, metformin, to a chemotherapy and radiation treatment regimen in head and neck cancer patients is not well tolerated if escalated too quickly, but allowing slower escalation could be beneficial. [More]
Study shows women with migraine history have rapid decline in estrogen levels

Study shows women with migraine history have rapid decline in estrogen levels

Researchers have long known that sex hormones such as estrogen play a role in migraine. But there's been little research on how that works. Do women with migraine have higher estrogen levels in general? Higher levels at the peak of the monthly cycle? [More]
Researchers call for more accurate renal assessment in stroke patients

Researchers call for more accurate renal assessment in stroke patients

Unrecognised renal insufficiency is common among patients with acute stroke and is associated with a significantly increased risk of in-hospital mortality or severe disability at discharge, say researchers. [More]
Renal function trajectories predict CV events in diabetes patients

Renal function trajectories predict CV events in diabetes patients

Steeper declines in renal function over time are associated with greater increases in the risk of major cardiovascular events among patients with Type 2 diabetes, research shows. [More]
Sodium excretion linked to CVD risk in chronic kidney disease

Sodium excretion linked to CVD risk in chronic kidney disease

High levels of sodium excretion are associated with a significantly increased risk of cardiovascular disease in patients with chronic kidney disease (CKD), US study findings indicate. [More]
Bare metal stents no longer advisable for high bleeding risk ACS patients

Bare metal stents no longer advisable for high bleeding risk ACS patients

A polymer-free, drug-coated stent gives markedly better outcomes than a bare metal stent in patients with acute coronary syndromes and risk factors for bleeding, report researchers. [More]
Phase I study of triple drug combination shows promise in multiple myeloma patients

Phase I study of triple drug combination shows promise in multiple myeloma patients

PharmaMar announces the positive results from a Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed and/or refractory multiple myeloma. [More]
New AVERT system can reduce radiographic dye volume in patients at risk of AKI

New AVERT system can reduce radiographic dye volume in patients at risk of AKI

In the largest study of its kind, a new device has been found to significantly reduce the volume of radiographic dye without decreasing image quality in patients who are at risk of developing acute kidney injury (AKI) after undergoing a coronary angiography or percutaneous coronary intervention (PCI). [More]
MR may detect earliest Alzheimer's brain changes

MR may detect earliest Alzheimer's brain changes

Levels of the brain metabolite and neuroinflammation marker myo-inositol are elevated in asymptomatic patients with abnormal Alzheimer's disease (AD) biomarkers, say researchers. As repo ... [More]
Person's age, mobility could be powerful predictors of survival than certain biomarkers

Person's age, mobility could be powerful predictors of survival than certain biomarkers

Advances in technology allow scientists to measure intricate details about the human body that greatly enhance understanding of health, disease and aging. [More]
Investigational drug provides no improved protection to patients with contrast-induced acute kidney injury

Investigational drug provides no improved protection to patients with contrast-induced acute kidney injury

Patients treated with CMX-2043--an investigational drug that has previously shown some ability to protect heart muscle from damage during stenting--saw no improved protection in their kidneys compared to placebo, according to research presented at the American College of Cardiology's 65th Annual Scientific Session. [More]
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