Crohn’s Disease News and Research

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FDA approves Humira (adalimumab) for Crohn's disease

The U.S. Food and Drug Administration (FDA) today approved Humira (adalimumab) to treat adult patients with moderately to severely active Crohn's disease, a chronic inflammatory disease of the intestines, which affects an estimated one million Americans.

27 Feb 2007

Surgical improvements for Crohn's disease sufferers

Decades of painstaking research has yielded the most in-depth look ever at the management of bowel stricture recurrence in patients who undergo surgery for Crohn's disease. The findings should provide much-needed guidance to surgeons and gastroenterologists battling this tough-to-manage intestinal disorder.

20 Feb 2007

Potential new cancer fighting drug found by mistake

Researchers in the United States appear to have almost inadvertently stumbled across what could be a new cancer treatment.

5 Feb 2007

Quality indicators for gastrointestinal endoscopic procedures

Defining measurements and identifying quality standards in the delivery of colonoscopic care is a major priority for the nation's leading gastrointestinal endoscopic healthcare association.

13 Sep 2006

Drug infliximab may help ease ulcerative colitis

In good news for patients with stubborn cases of ulcerative colitis, a serious intestinal disorder, a new research review suggests that the drug infliximab can be a useful alternative if other treatments don't work.

12 Sep 2006

Reduced levels of antiinflammatory cytokines in patients with chronic widespread pain

Chronic widespread pain, a common medical condition, can be difficult to treat and is often associated with fatigue, poor sleep and depression.

26 Jul 2006

Crohn's disease - possible genetic cause found

Patients with Crohn's disease of the colon have one copy less than healthy persons of the beta-defensin 2 gene, a gene coding for an important defense molecule of the body.

17 Jul 2006

Doctor who linked MMR jab to autism faces charges of serious professional misconduct

A British doctor who caused panic by suggesting that the measles, mumps and rubella (MMR) vaccine was linked to autism is to be charged with serious professional misconduct.

12 Jun 2006

Gene variation linked to more severe Crohn's disease

Building on previous evidence supporting the theory that the pathophysiology of Crohn's Disease is altered by genetic variation, recent studies have found that the combination of immune signals given by three variants of a single candidate gene affects the severity of the disease.

1 Jun 2006

Naltrexone relief for Crohn's sufferers

Study suggests that a drug used to ease symptoms of alcohol and drug addiction may also bring relief to people with Crohn's disease, a chronic inflammatory disorder of the intestine that affects an estimated 500,000 Americans.

31 May 2006

Research may lead to new treatments for intestinal disorders

University of Minnesota researchers have found a group of cells in the intestinal system of mice that are proven to turn on T-cells, cells that help fight infection.

24 May 2006

Arthritis drug wins approval for use in children with Crohn's disease

The Food and Drug Administration in the U.S. has given approval for the drug Remicade for use in children with active Crohn's disease(CD), a chronic and debilitating condition.

21 May 2006

Study shows strong association between treatment with TNF-blocking antibodies and development of serious infections

A new meta-analysis of many previous studies of TNF- (tumor necrosis factor) blocking antibodies for treatment of rheumatoid arthritis has confirmed a previously discovered increased risk for serious infection and has found that cancer also is a potential risk associated with the drugs.

17 May 2006

Remicade (infliximab) gains Australian approval for treatment of early rheumatoid arthritis

Schering-Plough Corporation today announced that the Therapeutic Goods Administration of the Department of Health and Ageing in Australia has revised the indication of Remicade (infliximab) to include the treatment of early rheumatoid arthritis (RA) and approved a new indication for psoriatic arthritis (PsA).

23 Mar 2006

Extensive study of natalizumab

Scientists have completed an extensive study of more than 3,000 patients who received a promising anti-inflammatory drug, natalizumab, that was linked to three cases of a serious brain infection in large clinical trials halted in early 2005.

7 Mar 2006

Data from Novogen inflammatory bowel disease drug Phase I clinical trial shows promise

A recently completed Phase 1 clinical trial of an investigational drug to treat inflammatory bowel disease has demonstrated rapid absorption indicating potential for development as an oral therapy.

6 Mar 2006

UCB submits application to FDA for new treatment in Crohn's disease

UCB has announced the submission of a Biologics License Application (BLA) to the United States Food and Drug Administration (FDA) for the approval of CIMZIA (certolizumab pegol, CDP870) for the treatment of patients with Crohn's disease.

6 Mar 2006

Is persistent bacterial infection good for your health?

Bacteria are bad. Mothers and doctors, not to mention the cleaning product industry, repeatedly warn of their dangers. But a Stanford University School of Medicine microbiologist is raising the intriguing idea that persistent bacterial and viral infections have benefits.

27 Feb 2006

Viagra could cure Crohn's disease

Crohn's disease is a chronic inflammatory bowel disorder which causes ulcerations in the gut and can make digesting food painful.

27 Feb 2006

Protein levels predict bone marrow transplant survival

Researchers say that protein levels can predict which bone marrow transplant patients are likely develop a deadly complication a week after the procedure and well before any symptoms occur.

19 Feb 2006