Crohn’s Disease News and Research

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Penn researchers single out bacterial enzyme behind gut microbiome imbalance linked to Crohn’s disease

Penn Medicine researchers have singled out a bacterial enzyme behind an imbalance in the gut microbiome linked to Crohn's disease.

16 Nov 2017

Study discovers new genetic risk loci linked to children's food allergies

What role do genes play in egg, milk, and nut allergies? A study published in Nature Communications, led by the Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, has found five genetic risk loci that point to the importance of skin and mucous membrane barriers and the immune system in the development of food allergies.

24 Oct 2017

MSC transplantation can be safe, effective approach to treat Crohn's disease-related fistula

A growing body of clinical evidence shows that transplantation of a patient's own mesenchymal stem cells (MSCs) to achieve a cure and prevent recurrent of Crohn's disease-related fistula can be a safe and effective addition to surgery.

14 Sep 2017

Researchers show that separate septic and aseptic procedure rooms is unnecessary

In Germany, the rule still applies that aseptic and septic and procedure rooms need to be separate; this is a requirement imposed by the Accident Insurance Provider for Hospitals.

8 Sep 2017

Exclusive enteral nutrition may be effective treatment for children with Crohn's disease

An analysis of published studies indicates that exclusive enteral nutrition (EEN)—when individuals receive only liquid nutrition—may be an effective treatment for children with Crohn's disease. The findings are published in Alimentary Pharmacology & Therapeutics.

23 Aug 2017

Home visits help new parents overcome tough histories, raise healthy children

Seated at a kitchen table in a cramped apartment, Rosendo Gil asked the young parents sitting across from him what they should do if their daughter caught a cold.

21 Aug 2017

Living in rural households lowers person's risk of developing IBD, study finds

Living in rural households decreases a person's risk of developing inflammatory bowel disease (IBD), particularly for young children and adolescents, according to a new study by researchers at the Children's Hospital of Eastern Ontario Research Institute, Institute for Clinical Evaluative Sciences, and the Canadian Gastro-Intestinal Epidemiology Consortium.

25 Jul 2017

Titanium dioxide nanoparticles can intensify inflammatory reaction in patients with colitis

Titanium dioxide, one of the most-produced nanoparticles worldwide, is being used increasingly in foodstuffs.

19 Jul 2017

Human colon organoids fill gap in effectively modeling common GI diseases

Scientists used human pluripotent stem cells to generate human embryonic colons in a laboratory that function much like natural human tissues when transplanted into mice, according to research published June 22 in Cell Stem Cell.

22 Jun 2017

Microscopic fungus exacerbates Crohn's disease symptoms, mice study shows

A microscopic fungus called Candida tropicalis triggered gut inflammation and exacerbated symptoms of Crohn's disease, in a recent study conducted at Case Western Reserve University School of Medicine.

22 Jun 2017

IBD patients with longer duration of disease have higher risk of developing NAFLD

Research led by a Houston Methodist gastroenterologist shows that patients who have inflammatory bowel disease (IBD) for more than two decades have a higher risk of developing nonalcoholic fatty liver disease (NAFLD).

5 Apr 2017

Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

Although anti-inflammatory treatments are quite effective at reducing symptoms in patients with Crohn's disease and ulcerative colitis, the mucosal lining of the intestine often remains ulcerated, and many patients still ultimately require surgery.

22 Mar 2017

New biomarkers may help in diagnosis and management of Crohn's disease

The diagnosis, understanding and management of Crohn's disease may have just received a helping hand from a joint ASU Biodesign Institute and Mayo Clinic study aimed at developing a better blood test for the disease.

9 Mar 2017

Mice study shows role of yeast in aggravating IBD symptoms

During the past decade, the gut has experienced a renaissance as investigations focus on the role of the microbiome on human health.

8 Mar 2017

DNA computer could be important step towards development of smart, 'intelligent' drugs

Researchers at Eindhoven University of Technology present a new method that should enable controlled drug delivery into the bloodstream using DNA computers.

17 Feb 2017

Researchers identify E. coli bacteria linking Crohn's disease to spondyloarthritis

Patients with Crohn's disease, a type of inflammatory bowel disease (IBD) that causes abdominal pain and diarrhea, can also experience joint pain.

9 Feb 2017

Pre-operative enteral nutrition linked to reduced rates of complications after Crohn's disease surgery

Despite improvements in medical care, about two-thirds of patients with Crohn's disease develop complications requiring intestinal surgery at some time, and post-operative healing can be complicated.

20 Jan 2017

New diet could treat pediatric patients with Crohn's disease, ulcerative colitis

In a first-of-its-kind study published today in the Journal of Clinical Gastroenterology, researchers from Seattle Children's and Children's Healthcare of Atlanta, led by Dr. David Suskind, a Seattle Children's gastroenterologist, found that diet alone can bring pediatric patients with active Crohn's disease and ulcerative colitis (UC) into clinical remission.

30 Dec 2016

New review provides insights on rates, predictors of relapse after surgery in Crohn's disease patients

Some patients with Crohn's disease, a chronic inflammatory disease that affects the lining of the digestive tract, require surgery to remove part or all of the large intestine; however, surgery does not cure the condition and many patients relapse after surgery.

8 Dec 2016

Arthritis drug induces response and remission in patients with Crohn's disease, study finds

Researchers at University of California San Diego School of Medicine have shown that ustekinumab, a human antibody used to treat arthritis, significantly induces response and remission in patients with moderate to severe Crohn's disease.

17 Nov 2016