Cross Linking News and Research

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Rethinking the germ theory: A balanced take on microbes and disease outcomes

Review explores the complexities of infectious disease outcomes through a balanced perspective, emphasizing the interplay between pathogenic microbes and host conditions, challenging the traditional germ-disease theory by proposing a more integrated view that considers both pathogen virulence and host immunity's impact on disease manifestation.

10 Apr 2024

Discovery of novel enzyme family holds potential for antibiotic development

Researchers at Umeå University in Sweden, led by Professor Felipe Cava, have identified a new family of enzymes that creates a unique type of cross-linking between the building blocks of bacterial cell walls.

19 Feb 2024

Study provides insight into potential mechanisms underlying diabetes-related disc tissue damage

Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal.

13 Feb 2024

DZNE neuroscientist awarded 1.5 million euros to investigate biophysical phenomena relevant to brain diseases

Dr. Dragomir Milovanovic, a neuroscientist at DZNE's Berlin site, has been awarded an European Research Council (ERC) "Starting Grant" worth 1.5 million euros to investigate biophysical phenomena relevant to brain diseases in a groundbreaking research project.

7 Nov 2023

Nanoengineered bioink improves tumor model accuracy

Scientists from the Terasaki Institute for Biomedical Innovation have developed a nanoengineered bioink with improved bonding and cross-linking capabilities for 3D bioprinting of tumor models.

3 Aug 2023

Novel biomaterials approach reveals how mechanical forces shape T cell fate

The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the same patient, especially against blood cancers is well under way.

26 Jun 2023

RNA regulatory mechanism could be targeted to slow AD progression mediated by stress granules

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."

1 Jun 2023

New toolkit enables in-vivo cross-linking of protein complexes in live cells

As the executor of life activities, proteins exert their specific biological functions through interactions such as forming protein complexes.

9 May 2023

New ‘artificial muscle’ material could someday operate safely in medical devices

Whether wriggling your toes or lifting groceries, muscles in your body smoothly expand and contract. Some polymers can do the same thing -; acting like artificial muscles -; but only when stimulated by dangerously high voltages.

12 Apr 2023

Menin protein protects against aging and cognitive decline

In a recent study published in the journal PLoS Biology, researchers from the University of Xiamen, China, explored the role of the hypothalamic menin in driving aging and associated cognitive decay.

23 Mar 2023

Researchers identify an enzyme associated with kidney fibrosis in both mice and humans

Researchers at Nagoya University in Japan have identified two enzymes that are involved in macrophage polarization, one of the key factors affecting fibrosis.

22 Mar 2023

Researchers synthesize fluorescent molecularly imprinted polymeric nanoparticles to detect neurotransmitters

The animal brain consists of tens of billions of neurons or nerve cells that perform complex tasks like processing emotions, learning, and making judgments by communicating with each other via neurotransmitters.

3 Mar 2023

Researchers find a way to block anaphylaxis caused by peanut allergies

Researchers from Indiana University School of Medicine have found a way to block anaphylaxis caused by peanut allergies.

9 Feb 2023

Structural studies pave the way for cancer drugs that could target only mutated versions

To design drugs that stall the growth of aggressive cancers, it helps to know the structures of the proteins that are revving the cancers' engines.

9 Dec 2022

Ultrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as an immunotherapy

Zika virus (ZIKV) infection is a potentially teratogenic illness, causing up to one in seven infants born to infected mothers to suffer neurodevelopmental deficits. A new study published in the journal Cell shows that some mothers escape injury to their babies because they develop a highly potent neutralizing antibody.

22 Nov 2022

Cross Linking News and Research

Rethinking the germ theory: A balanced take on microbes and disease outcomes

Discovery of novel enzyme family holds potential for antibiotic development

Study provides insight into potential mechanisms underlying diabetes-related disc tissue damage

DZNE neuroscientist awarded 1.5 million euros to investigate biophysical phenomena relevant to brain diseases

Nanoengineered bioink improves tumor model accuracy

Novel biomaterials approach reveals how mechanical forces shape T cell fate

RNA regulatory mechanism could be targeted to slow AD progression mediated by stress granules

New toolkit enables in-vivo cross-linking of protein complexes in live cells

New ‘artificial muscle’ material could someday operate safely in medical devices

Menin protein protects against aging and cognitive decline

Researchers identify an enzyme associated with kidney fibrosis in both mice and humans

Researchers synthesize fluorescent molecularly imprinted polymeric nanoparticles to detect neurotransmitters

Researchers find a way to block anaphylaxis caused by peanut allergies

Structural studies pave the way for cancer drugs that could target only mutated versions

Ultrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as an immunotherapy

Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Synthetic mucin gels against HIV-1 and HSV-2 transmission

Discovery of antibodies that may eliminate the need for COVID vaccines

Label-free trace detection of bio-molecules by LI-SERS method

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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