Crystallography News and Research RSS Feed - Crystallography News and Research

New study reveals key part of Ebola virus life cycle at higher resolution than ever before

New study reveals key part of Ebola virus life cycle at higher resolution than ever before

A new study led by scientists at The Scripps Research Institute (TSRI) reveals a key part of the Ebola virus life cycle at a higher resolution than ever before. The research sheds light on how Ebola virus assembles—and how researchers might stop the often-fatal infection. [More]
New research sheds light on molecular architecture of receptors linked to many brain diseases

New research sheds light on molecular architecture of receptors linked to many brain diseases

Scientists at The Scripps Research Institute have teamed up with several other institutions and pharmaceutical companies, including the University of Southern California (USC), San Diego's Receptos Inc. and Japanese company Ono Pharmaceutical Co., Ltd., to publish the first 3D structures of a receptor implicated in many diseases of the brain and in normal physiology throughout the body. [More]
Biochemists devise snappy new technique for blueprinting cell membrane proteins

Biochemists devise snappy new technique for blueprinting cell membrane proteins

Biochemists from Trinity College Dublin have devised a new technique that will make the difficult but critical job of blueprinting certain proteins considerably faster, cheaper and easier. [More]
Berkeley Lab offers 'on-demand' X-rays

Berkeley Lab offers 'on-demand' X-rays

Consumers are now in the era of "on-demand" entertainment, in which they have access to the books, music and movies they want thanks to the internet. Likewise, scientists who use synchrotron light sources are welcoming an era of "on-demand" X-rays, in which they have access to the light beams they want thanks to a technique developed at the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab). [More]
TSRI scientists map out protein structure involved in cellular function, nervous system development

TSRI scientists map out protein structure involved in cellular function, nervous system development

Scientists from The Scripps Research Institute, working closely with researchers at the National Institutes of Health, have mapped out the structure of an important protein involved in cellular function and nervous system development. [More]
Two world-renowned scientists receive Poland-U.S. Science Award

Two world-renowned scientists receive Poland-U.S. Science Award

World-renowned scientists -- Prof. Mariusz Jaskólski of Adam Mickiewicz University in Poznań, Poland, and Dr. Alexander Wlodawer of the National Cancer Institute, USA -- are the first winners of the Poland-U.S. Science Award granted jointly by the Foundation for Polish Science and the American Association for the Advancement of Science, the world's largest scientific association. [More]
New pre-validated fluorinated fragment library boosts drug screening efficiency

New pre-validated fluorinated fragment library boosts drug screening efficiency

Researchers engaged in drug discovery can now benefit from a new library of fluorinated compounds with superior drug-like characteristics... [More]
Researchers reveal molecular structure of cytotoxin from Mycoplasma pneumoniae

Researchers reveal molecular structure of cytotoxin from Mycoplasma pneumoniae

Researchers from the School of Medicine at The University of Texas Health Science Center at San Antonio today revealed the molecular structure of the cytotoxin from Mycoplasma pneumoniae, a widespread, highly contagious bacterium that infects the lungs. [More]
NIH awards $2.1 million grant to counter antibiotic resistance in Gram-negative bacteria

NIH awards $2.1 million grant to counter antibiotic resistance in Gram-negative bacteria

The National Institutes of Health has awarded Dr. Walter Fast, associate professor of medicinal chemistry at The University of Texas at Austin's College of Pharmacy, a four-year $2.1 million grant to develop small-molecules that counter antibiotic resistance in Gram-negative bacteria. If successful, the research could lead to new drugs for treating bacterial infections that are resistant to most antibiotics. [More]
Saccharin could potentially lead to development of drugs for difficult-to-treat cancers

Saccharin could potentially lead to development of drugs for difficult-to-treat cancers

Saccharin, the artificial sweetener that is the main ingredient in Sweet 'N Low, Sweet Twin and Necta, could do far more than just keep our waistlines trim. According to new research, this popular sugar substitute could potentially lead to the development of drugs capable of combating aggressive, difficult-to-treat cancers with fewer side effects. [More]

Winners of first SSPC National Crystal Growing Competition announced

The Synthesis and Solid State Pharmaceutical Centre today (19th March 2015) announced the winners of its first SSPC National Crystal Growing Competition, which was launched as part of Science Week in November 2014, to celebrate the International Year of Crystallography. The SSPC National Crystal Growing Competition was open to primary and post-primary schools from across Ireland. [More]
New research identifies promising drug therapy target for breast cancer

New research identifies promising drug therapy target for breast cancer

The genome of a cell is under constant attack, suffering DNA damage that requires an army of repair mechanisms to keep the cell healthy and alive. Understanding the behavior of the enzymes defending these assaults helps determine how - and where - cancer gets its foothold and flourishes. [More]
Weak spots in ebola’s defenses: an interview with Dr. Andrew Ward

Weak spots in ebola’s defenses: an interview with Dr. Andrew Ward

There are hundreds of other antibodies against Ebola that we are in the process of imaging using the electron microscope. We are looking for new sites of vulnerability as well as subtle differences in the way the known sites are attacked. In particular we are looking for antibodies that the virus is unlikely to escape from when it mutates. [More]
Nanobody Nano-85 holds promise for detection of noroviral RNA

Nanobody Nano-85 holds promise for detection of noroviral RNA

Infection with highly contagious noroviruses, while not usually fatal, can lead to a slew of unpleasant symptoms such as excessive vomiting and diarrhea. Current treatment options are limited to rehydration of the patient. "Additionally, noroviruses come in a variety of constantly evolving strains. [More]
Scientists uncover how primary protein responsible for multidrug resistance reacts to therapeutic drugs

Scientists uncover how primary protein responsible for multidrug resistance reacts to therapeutic drugs

Cancer patients fear the possibility that one day their cells might start rendering many different chemotherapy regimens ineffective. This phenomenon, called multidrug resistance, leads to tumors that defy treatment. [More]
TSRI researchers show how ABC transporters cause multidrug resistance

TSRI researchers show how ABC transporters cause multidrug resistance

Cancer patients fear the possibility that one day their cells might start rendering many different chemotherapy regimens ineffective. This phenomenon, called multidrug resistance, leads to tumors that defy treatment. [More]
U-M researchers reveal key role of two enzymes that help the body to remove cholesterol, other lipids

U-M researchers reveal key role of two enzymes that help the body to remove cholesterol, other lipids

With the aid of X-ray crystallography, researchers at the University of Michigan have revealed the structures of two closely related enzymes that play essential roles in the body's ability to metabolize excess lipids, including cholesterol. [More]
Researchers show how human antibodies can neutralize Marburg virus

Researchers show how human antibodies can neutralize Marburg virus

Researchers at Vanderbilt University, the University of Texas Medical Branch at Galveston and The Scripps Research Institute for the first time have shown how human antibodies can neutralize the Marburg virus, a close cousin to Ebola. [More]
Recipients of The 2015 Protein Society Awards announced

Recipients of The 2015 Protein Society Awards announced

The Protein Society, the premiere international society dedicated to supporting protein research, announces the winners of The 2015 Protein Society Awards. The awards will be conferred at the 29th Annual Symposium of The Protein Society (July 22-25, 2015, Barcelona, Spain). [More]
TSRI scientists find drug candidates that can prevent degeneration of brain cells in Parkinson's

TSRI scientists find drug candidates that can prevent degeneration of brain cells in Parkinson's

In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute have shown their drug candidates can target biological pathways involved in the destruction of brain cells in Parkinson's disease. [More]
Advertisement
Advertisement