Cyclophosphamide News and Research

RSS
Cyclophosphamide is a drug that is used to treat many types of cancer and is being studied in the treatment of other types of cancer. It is also used to treat some types of kidney disease in children. Cyclophosphamide attaches to DNA in cells and may kill cancer cells. It is a type of alkylating agent. Also called CTX and Cytoxan.

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death.
Timing of chemotherapy can have big effect on inflammation, study shows

Timing of chemotherapy can have big effect on inflammation, study shows

MUSC scientists design novel antibody-based therapy to fight against cancer

MUSC scientists design novel antibody-based therapy to fight against cancer

FDA approves expanded use of systemic therapy for treating chronic moderate-to-severe pediatric psoriasis

FDA approves expanded use of systemic therapy for treating chronic moderate-to-severe pediatric psoriasis

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

Researchers identify higher risk of early chemotherapy-related death in older patients with DLBCL

Researchers identify higher risk of early chemotherapy-related death in older patients with DLBCL

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

Everolimus combined with standard R-CHOP therapy shows promise in treating DLBCL patients

Everolimus combined with standard R-CHOP therapy shows promise in treating DLBCL patients

Scientists explain how engineered anthrax toxin proteins could help eliminate cancerous tumors

Scientists explain how engineered anthrax toxin proteins could help eliminate cancerous tumors

New stem cell treatment may halt clinical relapses, development of new brain lesions in patients MS

New stem cell treatment may halt clinical relapses, development of new brain lesions in patients MS

Tandem myeloablative ASCT consolidation boosts neuroblastoma outcomes

Tandem myeloablative ASCT consolidation boosts neuroblastoma outcomes

Immunoablation strengthens haemopoietic stem-cell transplantation effects in MS

Immunoablation strengthens haemopoietic stem-cell transplantation effects in MS

Immunotherapy with experimental monoclonal antibody could reduce neuroblastoma tumors

Immunotherapy with experimental monoclonal antibody could reduce neuroblastoma tumors

DECT trial shows combination of epirubicin and trastuzumab improves outcomes in breast cancer patients

DECT trial shows combination of epirubicin and trastuzumab improves outcomes in breast cancer patients

Cerebellar not cerebral atrophy predicts poor anti-NMDAR encephalitis outcome

Cerebellar not cerebral atrophy predicts poor anti-NMDAR encephalitis outcome

New drug combination before surgery may improve outcomes in breast cancer patients

New drug combination before surgery may improve outcomes in breast cancer patients

Autologous haematopoietic stem cell transplantation promise for myasthenia gravis

Autologous haematopoietic stem cell transplantation promise for myasthenia gravis

Key opinions leaders to discuss role of cyclophosphamide in the field of HSCT

Key opinions leaders to discuss role of cyclophosphamide in the field of HSCT

Fertility 'reassurance' for most chemotherapy-treated female childhood cancer survivors

Fertility 'reassurance' for most chemotherapy-treated female childhood cancer survivors

Women who have survived childhood cancer can become pregnant, shows study

Women who have survived childhood cancer can become pregnant, shows study

Multi-gene test can help identify early breast cancer patients who can safely be spared chemotherapy

Multi-gene test can help identify early breast cancer patients who can safely be spared chemotherapy