Cytokine News and Research

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Anti-malarials most effective in lupus patients genetically at risk of high levels of TNF-alpha

Anti-malarial drugs are most effective in people with lupus who are genetically predisposed to high levels of tumour necrosis factor alpha and low levels of the cytokine IL-10.

16 Feb 2006

Study may provide new hope for cancer patients

New study by Mount Sinai researchers may lead to improved stem cell therapies for patients with compromised immune systems due to intensive cancer therapy or autoimmune disease. The study is published in this week's issue of Cell.

27 Jan 2006

Protein finding could lead to new topical treatment for inflammatory diseases

A protein that undesirably shields a skin poxvirus from the immune system may become the key ingredient in a new topical treatment for inflammatory diseases, say medical researchers at the University of Illinois at Urbana-Champaign.

11 Jan 2006

Children could be saved from neuroblastoma using antibody therapy

Combination of T cell, antibody to neuroblastoma cells and molecule that spurs T cell growth is designed to treat low initial tumor levels or small cancer cell populations that survive initial treatment, according to St. Jude.

22 Dec 2005

Transport mechanisms for serotonin

Researchers at The Forsyth Institute have discovered that the transport mechanisms for serotonin - the chemical substance involved in transmitting signals between neurons, and which has a role in anxiety and mood disorders - play a key role in determining where organs are positioned in the body during embryonic development.

7 Dec 2005

Paclitaxel may help treat scleroderma

Using a novel model for scleroderma, researchers from Duke University Medical Center have discovered two important insights into this devastating disorder - the anti-cancer drug paclitaxel (Taxol) may prevent the skin thickening and small blood vessel destruction that characterizes the disease.

1 Nov 2005

Cichlid fish provide better understanding of the genetic factors that regulate bone shape

Researchers at the Forsyth Institute have discovered that the genes that influence the jaws of cichlid fish, tropical freshwater fish renowned for head shape diversity, offer insight into overall vertebrate diversity.

30 Oct 2005

Early nerve damage caused by repetitive strain injuries can trigger "sick worker" syndrome

...characterized by malaise, fatigue and depression, and often mistaken for poor performance, according to a study by Ann Barr, Ph.D., and Mary Barbe, Ph.D., at Temple University's College of Health Professions.

24 Oct 2005

Aging may intensify and prolong feeling run down when common infections like the flu occur

A new study, done with mice and published in the Federation of the American Societies of Experimental Biology Journal, suggests that miscommunication between the immune system and brain may be to blame for extended sickness symptoms and other cognitive disorders in elderly people and animals with an infection.

11 Oct 2005

Discovery of molecular roots of asthma, arthritis, and multiple sclerosis

The molecular roots of inflammatory and autoimmune diseases such as asthma, arthritis, and multiple sclerosis (MS) have been discovered by a team of researchers led by The University of Texas M. D. Anderson Cancer Center. They say their findings may point to ways to effectively treat these diseases - if not stop them before they start.

4 Oct 2005

Study shows that high-fat diets correlate to a chronic inflammatory state in the liver,

Mice that were fed diets high in fat and sugar developed immune system abnormalities in their livers, including reduced numbers of natural killer T (NKT) cells. These diet-related changes may contribute to obesity-related liver disease, according to a new study.

3 Oct 2005

Daylight savings changes may help extend the life and health of people's teeth and bones

Beginning in 2007, daylight savings time will be extended by almost a month. This additional amount of daylight may also help extend the life and health of people's teeth and bones. That's because vitamin D, also known as the "sunshine vitamin," is made by the body through casual and minimal sun exposure.

26 Sep 2005

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Researchers at The University of Texas M. D. Anderson Cancer Center and The University of Texas Health Science Center at Houston have found that human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke.

19 Sep 2005

Depression may hasten the progression of heart disease

In a study of 32 people with heart failure, the 14 patients who felt the most depressed had nearly twice the levels of this protein in their blood.

7 Sep 2005

Nitric oxide synthase plays a role in peripheral vascular disease

The enzyme nitric oxide synthase plays a role in peripheral vascular disease, a common disease that impairs the mobility of 25 percent of people over the age of 50, according to a Yale study in the Proceedings of the National Academy of Sciences (PNAS).

26 Aug 2005

Sirna Therapeutics granted new UK patents

Sirna Therapeutics has announced that the United Kingdom (UK) Patent Office has granted the Company two additional short interfering RNA (siRNA) target patents. The first patent covers any siRNA with one or more chemical modifications targeting Vascular Endothelial Growth Factor (VEGF).

12 Jul 2005

Cytokine News and Research

Anti-malarials most effective in lupus patients genetically at risk of high levels of TNF-alpha

Study may provide new hope for cancer patients

Protein finding could lead to new topical treatment for inflammatory diseases

Children could be saved from neuroblastoma using antibody therapy

Transport mechanisms for serotonin

Paclitaxel may help treat scleroderma

Cichlid fish provide better understanding of the genetic factors that regulate bone shape

Early nerve damage caused by repetitive strain injuries can trigger "sick worker" syndrome

Aging may intensify and prolong feeling run down when common infections like the flu occur

Discovery of molecular roots of asthma, arthritis, and multiple sclerosis

Study shows that high-fat diets correlate to a chronic inflammatory state in the liver,

Daylight savings changes may help extend the life and health of people's teeth and bones

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Depression may hasten the progression of heart disease

Nitric oxide synthase plays a role in peripheral vascular disease

Sirna Therapeutics granted new UK patents

Researchers have identified a highly specific pathway that causes inflammation in lung tissue

Psychosocial factors and interleukin-6 among women with advanced ovarian cancer

New diabetes drug has a double whammy and is a potential blockbuster

Gene therapy for arthritis is both feasible and safe

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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