Cytokine News and Research

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Man takes 217 COVID vaccines with no ill effects, shows immune boost

A case report of a 62-year-old man receiving 217 SARS-CoV-2 vaccinations over 29 months reveals no adverse effects, increased T-cells, and spike-specific antibodies, providing unique insights into the effects of hyper-vaccination on immune responses.

7 Mar 2024

Schisanhenol suppresses cytokine storm and acute lung injury in mice

Cytokine storm (CS) is an acute systemic inflammatory response with limited effective interventions up to now.

6 Mar 2024

Human molecular adaptations to fasting: Insights from proteomic analysis

Researchers investigate systemic proteome adaptations to one week of fasting in humans.

6 Mar 2024

Unlocking the secrets of T follicular helper cells for better treatment strategies

T follicular helper cells (Tfh) are essential for strong antibody-mediated reactions of our immune system during infections and vaccinations. However, if they get out of control, this can cause diseases such as autoimmunity, allergies or cancer.

1 Mar 2024

COVID-19's lasting mark: Long-term smell and taste loss

Study reveals prolonged olfactory and gustatory dysfunction in some COVID-19 recoverees, highlighting a need for better clinical support and understanding of long-term effects.

29 Feb 2024

Study reveals early death predictors in COVID-19 patients with cardiac injury

Announcing a new article publication for Cardiovascular Innovations and Applications journal. The activation of immune and thrombotic biomarkers at admission, and their ability to predict cardiac injury and mortality patterns in COVID-19, remains unclear.

26 Feb 2024

Natural killer cells lead the charge in cancer treatment innovation

Review synthesizes research on NK cells' role in cancer immunity and their potential in therapeutics through bioengineering, immune checkpoint inhibitors, and cell engagers, highlighting ongoing preclinical and clinical trials.

22 Feb 2024

Elevated IFN-γ levels linked to long COVID, study finds

Researchers find elevated IFN-γ levels in long COVID patients, with symptom improvement correlating with decreased IFN-γ, suggesting it as a potential biomarker and target for therapeutic intervention.

22 Feb 2024

MD Anderson acquires cell therapy safety technology from Bellicum Pharmaceuticals

The University of Texas MD Anderson Cancer Center today announced it has acquired certain assets from Bellicum Pharmaceuticals, Inc. related to the CaspaCIDe switch platform and the GoCAR platform.

22 Feb 2024

New study pinpoints key markers for Long COVID diagnosis

Study identifies elevated serologic responses and memory CD8+ T cell clonal expansion as key markers of Long COVID, offering insights into its pathology and potential diagnostic approaches.

18 Feb 2024

Smoking, infection, and BMI found to significantly sway immune response, study shows

Study reveals how smoking, CMV latent infection, and BMI significantly influence cytokine release, impacting immune response variability and potentially affecting disease risk.

14 Feb 2024

Black cumin: Ancient superseed with modern health benefits

Review discusses the multifaceted role of Nigella sativa in treating cardiometabolic diseases, highlighting its bioactive components like thymoquinone, which contribute to its antioxidant, anti-inflammatory, and anti-dyslipidemic properties.

13 Feb 2024

Mediterranean and vegetarian diets boost heart health by improving novel CVD markers

Study reveals that both lacto-ovo vegetarian and Mediterranean diets positively impact apolipoprotein levels and cardiovascular disease risk factors, with Mediterranean diet showing a more substantial effect on apolipoprotein levels, particularly in women and older individuals with fewer CVD risk factors.

13 Feb 2024

Cytokine interferon-gamma can be a disease-modifying therapeutic target in multiple system atrophy

Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain.

12 Feb 2024

Olive oil's secret weapon against Alzheimer's: phenolic compounds

A comprehensive review in the International Journal of Molecular Sciences highlights the potential of extra-virgin olive oil and its phenolic compounds in preventing and treating Alzheimer's disease through various mechanisms, including reducing amyloid-beta accumulation and neuroinflammation.

12 Feb 2024

Pregnant women show significant immune system changes linked to gut microbiome

How gut microbiota and metabolite changes relate to immune function during pregnancy.

12 Feb 2024

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

A new research perspective was published in Oncotarget's Volume 15 on February 5, 2024, entitled, "Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma."

8 Feb 2024

Monash-led study unveils potential long-term treatment for lupus

Researchers assessed Smith (Sm)-specific regulatory T cells (Tregs) efficacy in halting lupus nephritis (LN) by engineering and testing epitope-targeted Tregs for systemic lupus erythematosus (SLE) treatment.

8 Feb 2024

Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells (lining blood vessels), plays a crucial role in tumor progression.

7 Feb 2024

Gut microbiota alterations may influence immune system changes during pregnancy

During pregnancy, a woman's immune system changes dramatically but researchers don't yet understand all the underlying mechanisms.

7 Feb 2024

Cytokine News and Research

Man takes 217 COVID vaccines with no ill effects, shows immune boost

Schisanhenol suppresses cytokine storm and acute lung injury in mice

Human molecular adaptations to fasting: Insights from proteomic analysis

Unlocking the secrets of T follicular helper cells for better treatment strategies

COVID-19's lasting mark: Long-term smell and taste loss

Study reveals early death predictors in COVID-19 patients with cardiac injury

Natural killer cells lead the charge in cancer treatment innovation

Elevated IFN-γ levels linked to long COVID, study finds

MD Anderson acquires cell therapy safety technology from Bellicum Pharmaceuticals

New study pinpoints key markers for Long COVID diagnosis

Smoking, infection, and BMI found to significantly sway immune response, study shows

Black cumin: Ancient superseed with modern health benefits

Mediterranean and vegetarian diets boost heart health by improving novel CVD markers

Cytokine interferon-gamma can be a disease-modifying therapeutic target in multiple system atrophy

Olive oil's secret weapon against Alzheimer's: phenolic compounds

Pregnant women show significant immune system changes linked to gut microbiome

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

Monash-led study unveils potential long-term treatment for lupus

Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

Gut microbiota alterations may influence immune system changes during pregnancy

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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