Cytokine News and Research

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New nanoparticle adjuvant could help make vaccines more powerful

A common strategy to make vaccines more powerful is to deliver them along with an adjuvant -; a compound that stimulates the immune system to produce a stronger response.

3 Dec 2021

In-depth analysis of SARS-CoV-2 specific T cells in unexposed individuals

A new study aimed to analyze SARS-CoV-2 specific T-cells in unexposed individuals.

2 Dec 2021

Study explores the emergence and spread of SARS-CoV-2 Delta variant across Brazil

Brazilian researchers aim to determine the emergence and spread of the Delta VOC in different regions in Brazil.

2 Dec 2021

NEI researchers identify unique population of B cells that tamps down the immune system

Researchers at the National Eye Institute (NEI) have identified, isolated, and characterized a unique population of B cells that tamps down the immune system, reducing chronic inflammation.

2 Dec 2021

Advancing our understanding of T cells to improve cancer therapies

In this interview, News-Medical talks to Dr. Brendan Horton about his latest research which has shed new light on cancer and T cells.

2 Dec 2021

Impact of SARS-CoV-2 on oral health

New research examined SARS-CoV-2 and its impact on oral health and suggests that survival against the infection may be partially dependent on such factors.

1 Dec 2021

Role of interferon type I-driven responses associated with disease control in COVID-19

New research suggests that treatment with type I interferons in the early stage of COVID-19 may supress disease progression by limiting SARS-CoV-2 in hosts.

1 Dec 2021

Potentially neurotoxic SARS-CoV-2 protein fragments

Researchers investigate potentially amyloidogenic peptide fragments that could be associated with the neurological symptoms of COVID-19 and long-COVID.

30 Nov 2021

SARS-CoV-2 Delta spike increases viral virulence and inflammatory cytokine production

In a new study published on the bioRxiv* preprint server, scientists investigated several virological features of the Delta spike protein.

29 Nov 2021

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Researchers study human single nucleotide variants (SNVs) using machine learning to identify amino acid changes that alter kinase-bound sequence motifs.

29 Nov 2021

SARS-CoV-2 can directly invade human kidney cells, research shows

Up to 25% of patients' COVID-19 cases involve acute kidney injury—the kidneys' equivalent of a heart attack.

29 Nov 2021

Study finds atazanavir inhibits main SARS-CoV-2 protease

Research shows that ATV has different antiviral activity compared to PAXLOVID™, encouraging further research.

29 Nov 2021

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound known as interferon, allowing for the mitigation of coronavirus disease (COVID-19) severity. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

28 Nov 2021

Efficacy and safety of an RBD-based recombinant protein COVID-19 vaccine

A study developed a protein-based subunit vaccine, PHH-1V, that consisted of a recombinant RBD fusion heterodimer of the alpha) and beta variants of SARS-CoV-2.

26 Nov 2021

Study explores adverse effects of SARS-CoV-2-induced antibody responses

The authors of a research paper published in the journal Frontiers in Immunology used Sandwich ELISA tests to determine the distribution of IgG sub-classes and complement activation levels in plasma from convalescent individuals.

25 Nov 2021

Maternal-fetal interface yields intriguing clues to how it battles SARS-CoV-2

Scientists have hypothesized that the number of immune cells and the amount of cytokines produced in response to SARS-CoV-2 infection in pregnant women change in accordance with the timing of maternal infection in pregnancy. This study is available on the bioRxiv* preprint server.

24 Nov 2021

Study identifies small RNA molecule as a therapeutic target for COPD

Research led by the Centenary Institute and University of Technology Sydney (UTS) has identified a small RNA molecule called microRNA-21 as a therapeutic target and its inhibition as a potential treatment for chronic obstructive pulmonary disease (COPD).

24 Nov 2021

Cytokine News and Research

New nanoparticle adjuvant could help make vaccines more powerful

In-depth analysis of SARS-CoV-2 specific T cells in unexposed individuals

Study explores the emergence and spread of SARS-CoV-2 Delta variant across Brazil

NEI researchers identify unique population of B cells that tamps down the immune system

Advancing our understanding of T cells to improve cancer therapies

Impact of SARS-CoV-2 on oral health

Role of interferon type I-driven responses associated with disease control in COVID-19

Potentially neurotoxic SARS-CoV-2 protein fragments

SARS-CoV-2 Delta spike increases viral virulence and inflammatory cytokine production

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

SARS-CoV-2 can directly invade human kidney cells, research shows

Study finds atazanavir inhibits main SARS-CoV-2 protease

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

Efficacy and safety of an RBD-based recombinant protein COVID-19 vaccine

Study explores adverse effects of SARS-CoV-2-induced antibody responses

Maternal-fetal interface yields intriguing clues to how it battles SARS-CoV-2

Study identifies small RNA molecule as a therapeutic target for COPD

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

Inactivated virion-based vaccine confers robust cell-mediated immunity against major SARS-CoV-2 variants

Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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