Cytomegalovirus News and Research

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Cytomegalovirus (CMV) is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella-zoster virus (which causes chickenpox), and Epstein-Barr virus (which causes infectious mononucleosis). Infection with CMV is a major cause of disease and death in immunocompromised patients, including organ transplant recipients, patients undergoing hemodialysis, patients with cancer, patients receiving immunosuppressive drugs, and HIV-infected patients. While drugs are available for treatment of these conditions, the primary drug choices carry significant side effects and warnings. Currently, there are no anti-CMV drugs indicated for treatment of primary CMV infection during pregnancy resulting in infections that can have catastrophic consequences to the newborn. Maternal-fetal transfer of CMV infection results in a fetal death rate of 12% and most survivors have permanent debilitating disorders, including mental retardation, vision loss, and sensorineural deafness.

Further Reading

Young researchers explore impact of prolonged Zika viremia in pregnant women, fetuses and infants

Young researchers explore impact of prolonged Zika viremia in pregnant women, fetuses and infants

Johns Hopkins researchers find no evidence of CMV in aggressive brain cancer tissues

Johns Hopkins researchers find no evidence of CMV in aggressive brain cancer tissues

Genetic variation may be reason for overreaction of immune system to viruses

Genetic variation may be reason for overreaction of immune system to viruses

Novel antiviral drug can protect transplant patients against CMV infections

Novel antiviral drug can protect transplant patients against CMV infections

Utah law increases early identification of infants with hearing loss, new study reveals

Utah law increases early identification of infants with hearing loss, new study reveals

Penn State researchers develop novel compound to combat cytomegalovirus

Penn State researchers develop novel compound to combat cytomegalovirus

Genetic mutation may increase susceptibility to cytomegalovirus infection

Genetic mutation may increase susceptibility to cytomegalovirus infection

Newborns with CMV may have increased risk of developing acute lymphocytic leukemia

Newborns with CMV may have increased risk of developing acute lymphocytic leukemia

Japanese researchers discover new method for predicting congenital CMV infection in fetuses

Japanese researchers discover new method for predicting congenital CMV infection in fetuses

Congenital CMV infection highly common among children with cerebral palsy, study finds

Congenital CMV infection highly common among children with cerebral palsy, study finds

Researchers develop new way to prevent diseases caused by herpesvirus infections

Researchers develop new way to prevent diseases caused by herpesvirus infections

Researchers develop new way to test strength of immune response

Researchers develop new way to test strength of immune response

Study provides potential new target to combat cytomegalovirus infections

Study provides potential new target to combat cytomegalovirus infections

First case-control study examines link between microcephaly and in utero Zika virus infection

First case-control study examines link between microcephaly and in utero Zika virus infection

Malformations in the brains of fetuses caused by Zika virus go beyond microcephaly

Malformations in the brains of fetuses caused by Zika virus go beyond microcephaly

UNMC researcher aims to find workable solution for tackling antibiotic resistance

UNMC researcher aims to find workable solution for tackling antibiotic resistance

HHV-6A human herpesvirus infects uterus lining of women with unexplained infertility

HHV-6A human herpesvirus infects uterus lining of women with unexplained infertility

Study highlights role of CMV in patients with leukemia after bone marrow transplantation

Study highlights role of CMV in patients with leukemia after bone marrow transplantation

Disrupted fetal immune system increases later risk of neurodevelopmental diseases

Disrupted fetal immune system increases later risk of neurodevelopmental diseases

T memory cells with naive phenotype can help boost immunity in older adults

T memory cells with naive phenotype can help boost immunity in older adults