Depressive Disorder News and Research

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Behavioral activation vs antidepressants: Which wins for heart failure patients with depression?

The efficacy of antidepressant medication management (MEDS) against behavioral activation psychotherapy (BA).

17 Jan 2024

Largest study using machine learning in neuroimaging sets new benchmark for major depression diagnosis

A benchmark classification of major depressive disorder (MDD) using machine learning (ML).

15 Jan 2024

Study identifies more than 200 new genes linked to depression

More than 200 genes linked to depression have been newly identified in a worldwide study led by UCL researchers.

10 Jan 2024

Leaky gut linked to depressive disorders: New insights into microbiota-induced epigenetic changes

A study in the journal Genes highlights how a leaky gut can lead to depressive disorders through changes in gut microbiota-derived metabolites, emphasizing the role of diet, environmental factors, and probiotics in managing these conditions.

18 Dec 2023

Psilocybin may benefit individuals with cancer and major depression

Results from a phase II clinical trial indicate that psilocybin, a hallucinogenic chemical found in certain mushrooms of the genus Psiloybe, may benefit individuals with cancer and major depression.

18 Dec 2023

Researchers reveal a connection between cellular metabolism and depression, suicidal ideation

Major depressive disorder affects 16.1 million adults in the United States and costs $210 billion annually. While the primary symptoms of depression are psychological, scientists and doctors have come to understand that depression is a complex disease with physical effects throughout the body.

15 Dec 2023

COVID-19 vaccination eased anxiety, insomnia, and depression in Chinese adults, study finds

Study reveals that COVID-19 vaccination significantly reduces the prevalence of anxiety, insomnia, and depression symptoms among Chinese adults, with vaccinated individuals reporting lower severity of these conditions compared to non-vaccinated individuals.

13 Dec 2023

Study assesses links between early negative life events, orbitofrontal cortical thickness and depression in young adults

Study found that early negative life events predict depressive symptoms in young adulthood, but not through accelerated thinning of the orbitofrontal cortex (OFC) across adolescence, challenging previous assumptions about the brain's structural changes and mental health.

10 Dec 2023

Novel TMS protocol shows promise for treating hard-to-treat depression

By making slight modifications to an already approved brain stimulation technique called transcranial magnetic stimulation (TMS), researchers have reported profound improvement in patients with hard-to-treat depression.

29 Nov 2023

Science tackles mental health: New tools against anxiety and depression in a stressed world

This review in the Proceedings of the National Academy of Sciences discusses the role of scientific tools in combating mental health disorders like anxiety, MDD, and PTSD, emphasizing the need for a deep scientific understanding and diverse treatment approaches in the face of a global surge in psychological stress. The study explores stress biology, treatment strategies, and the importance of personalized scientific approaches to effectively address the mental health crisis.

29 Nov 2023

The potential of polyunsaturated fatty acids in alleviating depression and reducing suicide risk

Research in 'Molecular Psychiatry' explores the role of long-chain polyunsaturated fatty acids (LC-PUFAs) in major depressive disorder (MDD) and suicide risk, showing mixed results in clinical trials for depression treatment. The study underscores the need for further investigation into LC-PUFAs' neurobiology to advance personalized medicine for mood disorders and suicide prevention.

26 Nov 2023

A review of automated clinical depression diagnosis tools

A review on how the latest computational methods that utilize facial, acoustic, and semantic features are being deployed to predict major depressive disorders.

23 Nov 2023

Significant genetic variations linked to cannabis use disorder identified in major global ancestries

Multi-ancestry genome-wide association study of cannabis use disorder.

22 Nov 2023

Precision TMS approach yields improved outcomes for patients with major depressive symptoms

A new study from UCLA Health researchers demonstrates that a novel treatment is effective in most patients with major depressive symptoms even after multiple failed courses of antidepressant medication.

20 Nov 2023

Novel antidepressant zuranolone effective in alleviating depression and anxiety symptoms

The efficacy and safety of zuranolone in treating major depressive disorder (MDD).

20 Nov 2023

Eating disorder claim lines increase significantly from 2018 to 2022

From 2018 to 2022, eating disorder claim lines increased 65 percent nationally as a percentage of all medical claim lines.

15 Nov 2023

Transforming brain research with AI and machine learning

Using machine learning, researchers are able to use data from the brain to glean deeper insights and apply this new knowledge in clinical settings.

13 Nov 2023

Study suggests concomitant antidepressant and statin use could prevent treatment discontinuation

A recent study in the journal BMC Medicine evaluates the real-world impact of combining antidepressants with statins in UK adults, revealing lower discontinuation rates but similar efficacy compared to antidepressant-only treatment.

12 Nov 2023

Study shows depression increases disability risk in rheumatoid arthritis sufferers

The interactions between rheumatoid arthritis (RA) and major depressive disorder (MDD).

7 Nov 2023

Study unveils the neurobiological underpinnings of adolescent major depressive disorder

Published in the 2023 Volume 3 issue of Psychoradiology a team of dedicated researchers from South China Normal University delved deep into the unique brain network dysfunctions present in adolescents with MDD.

3 Nov 2023