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Weight loss through lifestyle modifications, bariatric surgery can reduce features of NASH

Weight loss through lifestyle modifications, bariatric surgery can reduce features of NASH

Weight loss through both lifestyle modification and bariatric surgery can significantly reduce features of nonalcoholic steatohepatitis (NASH), a disease characterized by fat in the liver, according to two new studies published in Gastroenterology, the official journal of the American Gastroenterological Association. [More]
UChicago, Argonne National Laboratory and USF to jointly study gut microbiomes of premature infants

UChicago, Argonne National Laboratory and USF to jointly study gut microbiomes of premature infants

Scientists have suspected that this initial disruption is linked to health problems down the road—things like autism, asthma, food allergies and autoimmune diseases—but so far they only have circumstantial evidence based on case studies. [More]
Bacterial biofilms play role in development of systemic lupus erythematosus

Bacterial biofilms play role in development of systemic lupus erythematosus

Lupus, multiple sclerosis, and type-1 diabetes are among more than a score of diseases in which the immune system attacks the body it was designed to defend. But just why the immune system begins its misdirected assault has remained a mystery. [More]
Celtaxsys receives FDA clearance to begin acebilustat Phase 2 trial in adult CF patients in the US

Celtaxsys receives FDA clearance to begin acebilustat Phase 2 trial in adult CF patients in the US

Celtaxsys, Inc., a clinical stage pharmaceutical development company focusing on anti-inflammatory therapeutics, including those with rare and orphan inflammatory disease indications, announced today that it has gained clearance from the U.S. Food and Drug Administration to begin a Phase 2 clinical trial of its flagship drug candidate, acebilustat (CTX-4430), in adult CF patients in the US. [More]
Biologically active molecules produced during gluten digestion can pass through gut lining

Biologically active molecules produced during gluten digestion can pass through gut lining

Biologically active molecules released by digesting bread and pasta can survive digestion and potentially pass through the gut lining, suggests new research. [More]
Study opens up new line of research into origin of digestive diseases

Study opens up new line of research into origin of digestive diseases

There are numerous studies related to the absorption of nutrients from the stomach since understanding what happens in our digestive system is crucial, for example, in order to be able to avoid in the future some of the diseases that affect part of the population to a lesser or greater extent. [More]
High-fat, high-sugar diet can cause bacterial changes that appear related to loss of 'cognitive flexibility'

High-fat, high-sugar diet can cause bacterial changes that appear related to loss of 'cognitive flexibility'

A study at Oregon State University indicates that both a high-fat and a high-sugar diet, compared to a normal diet, cause changes in gut bacteria that appear related to a significant loss of "cognitive flexibility," or the power to adapt and adjust to changing situations. [More]
Pulmatrix announces new inhaled anti-infective therapy to treat CF-associated fungal infections

Pulmatrix announces new inhaled anti-infective therapy to treat CF-associated fungal infections

Pulmatrix, Inc., a clinical stage biopharmaceutical company developing innovative inhaled therapies for serious pulmonary diseases, today announced a new drug candidate, PUR1900, an inhaled anti-infective to treat fungal infections associated with cystic fibrosis (CF). [More]
Celtaxsys closes $40M Series D financing and receives $5M CFFT grant to conduct CTX-4430 Phase 2 trial

Celtaxsys closes $40M Series D financing and receives $5M CFFT grant to conduct CTX-4430 Phase 2 trial

Celtaxsys, Inc., a clinical stage drug development company focused on developing novel therapies for inflammatory diseases, today announced the successful completion of a $40M Series D financing led by Domain Partners VIII. Additional investors in the financing include Lumira Capital, RMI Partners, Masters Capital Management and the Georgia Research Alliance Venture Fund. [More]
Game changing, breakthrough early cancer detection technology presented at ASCO 2015

Game changing, breakthrough early cancer detection technology presented at ASCO 2015

Anpac Bio-Medical Science Co., Ltd., Chief Executive Officer and Scientist Dr. Chris Yu and the Anpac research team are introducing what the 2015 Nobel Prize Laureate Summit on Biomedical Science (NPLS) organizers published as, "game changing" and "breakthrough" early cancer detection technology research results at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, Illinois, May 29 – June 2, 2015. [More]
Clinical utility of Caris Molecular Intelligence in five studies to be presented at ASCO 2015

Clinical utility of Caris Molecular Intelligence in five studies to be presented at ASCO 2015

Caris Life Sciences, a leading biotechnology company focused on fulfilling the promise of precision medicine, today announced the presentation of data from five studies that demonstrate the clinical utility of Caris Molecular Intelligence®, the company's panomic comprehensive tumor profiling service, in helping to identify targeted treatment options for patients with rare and/or aggressive tumors. [More]
Overweight and inflammation during adolescence may increase colorectal cancer risk later in life

Overweight and inflammation during adolescence may increase colorectal cancer risk later in life

Being very overweight in your teens doubles the risk of developing colorectal cancer later in life compared to those whose weight was within the normal range a new Swedish study suggests. The research team behind the study are from örebro University in Sweden and Harvard School of Public Health in the US. [More]
New study reveals that 'imperfect drug penetration' can accelerate pathogens' resistance

New study reveals that 'imperfect drug penetration' can accelerate pathogens' resistance

Prescribing patients two or more drugs that do not reach the same parts of the body could accelerate a pathogen's resistance to all of the drugs being used in treatment, according to a new study published today in the Proceedings of the National Academy of Sciences. [More]
Simple blood tests diagnose irritable bowel syndrome quickly and accurately

Simple blood tests diagnose irritable bowel syndrome quickly and accurately

Millions of people afflicted by irritable bowel syndrome can now be diagnosed quickly and accurately with two simple blood tests developed by a Cedars-Sinai gastroenterologist. [More]
Special issue of Gastroenterology highlights how food impacts health and disease

Special issue of Gastroenterology highlights how food impacts health and disease

Patients are always interested in understanding what they should eat and how it will impact their health. Physicians are just as interested in advancing their understanding of the major health effects of foods and food-related diseases. [More]
Yale researchers successfully correct gene mutation that causes cystic fibrosis

Yale researchers successfully correct gene mutation that causes cystic fibrosis

Yale researchers successfully corrected the most common mutation in the gene that causes cystic fibrosis, a lethal genetic disorder. The study was published April 27 in Nature Communications. [More]
Understanding how nerve cells in the brain produce energy required to function

Understanding how nerve cells in the brain produce energy required to function

New research published today in the journal Nature Communications represents a potentially fundamental shift in our understanding of how nerve cells in the brain generate the energy needed to function. The study shows neurons are more independent than previously believed and this research has implications for a range of neurological disorders. [More]
May issues of AGA's journals highlight important research updates on liver disease

May issues of AGA's journals highlight important research updates on liver disease

The May issues of AGA's journals -- Clinical Gastroenterology and Hepatology and Gastroenterology -- highlight important research updates on the most deadly forms of liver disease. [More]
New research could transform treatments for patients with Barrett's Oesophagus

New research could transform treatments for patients with Barrett's Oesophagus

New research from the University of Warwick and University Hospitals Coventry and Warwickshire NHS Trust could transform treatments and diagnosis for a common digestive condition which affects thousands of patients. [More]
Every third teenager reports one mental disorder, one chronic physical disease

Every third teenager reports one mental disorder, one chronic physical disease

Every third teenager has suffered from one mental disorder and one physical disease. These co-occurrences come in specific associations: More often than average, depression occurs together with diseases of the digestive system, eating disorders with seizures and anxiety disorders together with arthritis, heart disease as well as diseases of the digestives system. [More]
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