Dihydrotestosterone News and Research

RSS

Dihydrotestosterone (DHT) is a biologically active metabolite of the hormone testosterone, formed primarily in the prostate gland, testes, hair follicles, and adrenal glands

Exploring the impact of soy isoflavones in prostate cancer therapy

The cellular mechanisms of soy isoflavones, genistein, daidzein, and equol.

23 Nov 2023

Can human chorionic gonadotropin supplements enhance penile growth?

Whether human chorionic gonadotropin could expedite tunica albuginea restructuring to aid penile development.

4 Oct 2023

Men with sneaky testosterone physiology have worse prostate cancer outcomes, study finds

First-of-its-kind study on 266 men found 20% have higher levels of the hormone in the vessels surrounding the prostate.

4 Sep 2023

How B-cells and androgens contribute to the development of PCOS

Researchers evaluate the role of B-cell frequencies in the pathogenesis of polycystic ovary syndrome.

9 Jul 2023

Unique plant extract mixture has potent anti-acne effects

Researchers evaluate the efficacy of FRO, a formula composed of fermented Rhus verniciflua Stokes and Orostachys japonicus, against acne pathogenesis via antimicrobial assessment and an in vitro analysis. FRO was found to contain phenolics such as gallic acid, fisetin, quercetin, and kaempferol and was determined to alleviate acne by inhibiting the growth of Cutibacterium acnes, inflammation, and excess sebum.

9 Jul 2023

Passing on Polycystic Ovary Syndrome: Health risks for Male offspring of Women with PCOS

In this interview, we spoke to two researchers from the Karolinska Institutet about their latest work that investigated how PCOS can affect the health of future generations of men.

29 May 2023

COVID-19 impairs the insulin/IGF signaling pathway

Scientists evaluate the impact of SARS-CoV-2 on the insulin/IGF signaling pathway.

6 Jul 2022

COVID-19 can cause metabolism problems by interfering with insulin signaling, study reveals

It has become abundantly clear that coronavirus disease 19 (COVID-19), despite being transmitted by breathing in the SARS-CoV-2 virus, can have harmful effects far beyond the lungs.

27 Jun 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

Study evaluates efficacy of isotretinoin in improving COVID-19 outcomes

Researchers evaluated the effectiveness of isotretinoin (13-cis retinoic acid) in improving COVID-19 outcomes.

14 Mar 2022

City of Hope initiates Phase 2 clinical trial to investigate if mushroom tablets could slow prostate cancer

City of Hope, a world-renowned independent research and treatment center for cancer, diabetes and other life-threatening diseases, is now recruiting patients for a Phase 2 clinical trial to investigate whether pills containing white button mushroom extract could regulate the immune system, affecting prostate-specific antigen (PSA) levels to either remain stable or decline.

29 Apr 2021

Diet may help restore ovulation in women with polycystic ovary syndrome

The Mediterranean diet may be investigated as a possible treatment for polycystic ovary syndrome after mice with PCOS-like features of the condition were found to benefit from a similar diet.

21 Oct 2020

Testosterone is not the only hormone needed for penis development

A new study has revealed that in addition to testosterone, the masculinization process involves a hormone called androsterone, which originates in other tissues.

15 Feb 2019

Study identifies RNA molecules that regulate male hormones in prostate cancer

In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone.

19 Jul 2018

Maternal obesity and androgen excess induce sex-specific anxiety in offspring, study suggests

Maternal obesity and androgen excess induce sex-specific anxiety in the offspring, according to a study on mice by researchers at Karolinska Institutet in Sweden published in The FASEB Journal.

22 Mar 2018

Prolonged exposure to male hormone blockers increases risk of persistent erectile dysfunction

Men with longer exposure to the drugs finasteride and dutasteride had a higher risk of getting persistent erectile dysfunction than men with less exposure, reports a new Northwestern Medicine study.

9 Mar 2017

Misuse of anabolic steroids may increase heart problems in ARVC patients

Research has already shown that taking anabolic steroids is associated with high blood pressure and an increased risk of developing heart conditions such as left ventricular hypertrophy.

6 Jun 2016

AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

Prostate cancer is the second leading cause of mortality among American men with the highest incidence rate of all cancers reported in the U.S. Male sex hormones testosterone (T) and 5α-dihydrotestosterone (5α-DHT) promote prostate cancer progression.

19 May 2016

Infant daughters may show early signs of PCOS from mothers

The infant daughters of women with polycystic ovary syndrome (PCOS) show a higher level of an enzyme that activates testosterone and may be an early sign of developing the complex genetic disease, according to a new Northwestern Medicine study.

7 Apr 2016

Serum testosterone may decline due to decreased sexual activity and desire in older men

In older men, decreased sexual activity and desire, not erectile dysfunction, may cause serum testosterone to decline, a new study from Australia finds. The results will be presented Saturday March 7, at ENDO 2015, the annual meeting of the Endocrine Society, in San Diego.

9 Mar 2015