Dopamine News and Research RSS Feed - Dopamine News and Research

Dopamine is a hormone and neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine has many functions in the brain, including important roles in behavior and cognition, motor activity, motivation and reward, inhibition of prolactin production (involved in lactation), sleep, mood, attention, and learning. Dopaminergic neurons (i.e., neurons whose primary neurotransmitter is dopamine) are present chiefly in the ventral tegmental area (VTA) of the midbrain, substantia nigra pars compacta, and arcuate nucleus of the hypothalamus.
New drug delivery system by Renishaw hopes to aid Parkinson’s treatment

New drug delivery system by Renishaw hopes to aid Parkinson’s treatment

Renishaw’s novel drug delivery system, to be used in partnership with Herantis Pharma Plc’s drug candidate CDNF for the treatment of Parkinson’s disease, is about to enter phase 1-2 clinical trials. The study will be supported by a €6 million grant from Horizon 2020, the European Union’s Framework Programme for Research and Innovation. [More]
Hormonal fluctuations make women more sensitive to addictive properties of cocaine, study reveals

Hormonal fluctuations make women more sensitive to addictive properties of cocaine, study reveals

Hormonal fluctuations women undergo make them particularly sensitive, compared to men, to the addictive properties of cocaine, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published January 10 in the journal Nature Communications. [More]
Study reveals how migration increases person's risk of developing schizophrenia

Study reveals how migration increases person's risk of developing schizophrenia

A new study could explain how migrating to another country increases a person's risk of developing schizophrenia, by altering brain chemistry. [More]
Biological Psychiatry special issue highlights role of dopamine signaling in schizophrenia

Biological Psychiatry special issue highlights role of dopamine signaling in schizophrenia

Biological Psychiatry presents a special issue, "The Dopamine Hypothesis of Schizophrenia", dedicated to recent advances in understanding the role of dopamine signaling in schizophrenia. [More]
Physical inactivity in obese mice linked to dopamine signaling defects

Physical inactivity in obese mice linked to dopamine signaling defects

Starting a regular program at the gym is a common New Year's resolution, but it's one that most people are unable to stick with for very long. [More]
Music may regulate mood, emotional responses at behavioral and neuronal level

Music may regulate mood, emotional responses at behavioral and neuronal level

Sounds, such as music and noise, are capable of reliably affecting individuals' moods and emotions, possibly by regulating brain dopamine, a neurotransmitter strongly involved in emotional behavior and mood regulation. [More]
MedUni Vienna scientists show that addictive cravings can be detected after death

MedUni Vienna scientists show that addictive cravings can be detected after death

A protein known as FosB in the reward centre of the brain alters in chronically ill people suffering from an addictive disorder (e.g. heroin addiction): it is genetically modified, split off and shortened. [More]
QUT neuroscientist shows how brainpower could be key to mange stress and lose weight

QUT neuroscientist shows how brainpower could be key to mange stress and lose weight

A QUT neuroscientist internationally acclaimed for her research on alcohol and sugar addiction claims brainpower rather than willpower is the key to living healthily. [More]
Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine. [More]
Scientists devise new radiation-free probe for imaging molecules in the brain

Scientists devise new radiation-free probe for imaging molecules in the brain

Scientists hoping to get a glimpse of molecules that control brain activity have devised a new probe that allows them to image these molecules without using any chemical or radioactive labels. [More]
TSRI scientists discover potential drug candidate to suppress pain and itch

TSRI scientists discover potential drug candidate to suppress pain and itch

In a new study, scientists from the Florida campus of The Scripps Research Institute have identified a possible drug candidate that suppresses pain and itch in animal models. [More]
Scientists identify microrna that provides clues for quieting auditory hallucinations of schizophrenia

Scientists identify microrna that provides clues for quieting auditory hallucinations of schizophrenia

St. Jude Children's Research Hospital scientists have identified a small RNA (microRNA) that may be essential to restoring normal function in a brain circuit associated with the "voices" and other hallucinations of schizophrenia. [More]
Gene mutation appears to increase risk of Parkinson's disease in Caucasians

Gene mutation appears to increase risk of Parkinson's disease in Caucasians

A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson's disease, according to new research from Iowa State University. The effect is particularly dramatic for people under age 50. [More]
Pharmacotherapy combined with rehabilitation program offers hope for traumatic brain injury patients

Pharmacotherapy combined with rehabilitation program offers hope for traumatic brain injury patients

Pharmacological therapy combined with a rehabilitation program that teaches how to compensate for memory and attention problems offers new hope for people who suffer the consequences of traumatic brain injury. [More]
TSRI scientists discover precise signaling mechanisms that regulate brain’s motor function

TSRI scientists discover precise signaling mechanisms that regulate brain’s motor function

In new findings that could have an impact the development of therapies for a number of currently untreatable brain disorders such as Parkinson’s and Huntington’s diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have found, for the first time, that a specific signaling circuit in the brain is deeply involved in motor activity. [More]
New 3D scene analysis could supplement usual methods for monitoring sleep disorders

New 3D scene analysis could supplement usual methods for monitoring sleep disorders

The usual method of recording periodic leg movements in sleep for people with sleep disorders is to use electromyography (EMG), an electrophysiological method used in neurological diagnosis that measures muscle activity. [More]
Research sheds new light on how humans learn to behave under uncertainty

Research sheds new light on how humans learn to behave under uncertainty

New research has revealed how three important brain signaling chemicals affect the way that we handle uncertainty. [More]
UTHealth study receives $1.9 million NIH grant to identify effective treatment for cocaine addiction

UTHealth study receives $1.9 million NIH grant to identify effective treatment for cocaine addiction

Identifying more effective treatment strategies tailored to individual responses for patients overcoming addiction to cocaine is the focus of a new clinical trial at McGovern Medical School at The University of Texas Health Science Center at Houston. [More]
Researcher develops nature-inspired adhesive that stays sticky when wet

Researcher develops nature-inspired adhesive that stays sticky when wet

Even the strongest glues collapse when soaked. Just watch a band-aid slide ungracefully off a finger or toe while in the shower. However, with support from the Office of Naval Research, one researcher has developed a nature-inspired adhesive that stays sticky when wet. [More]
Study reveals way to actively reverse anesthetic-induced unconsciousness

Study reveals way to actively reverse anesthetic-induced unconsciousness

The latest study from a Massachusetts General Hospital/Massachusetts Institute of Technology team investigating the mechanisms underlying general anesthesia finds that stimulating a specific group of neurons in mice produces signs of arousal -- including getting on their feet and walking -- even as the animals continue to receive the anesthetic drug isoflurane. [More]
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