Drug Resistant Tuberculosis News and Research

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TB Alliance announces initiation of first human trial of new TB drug candidate

TB Alliance has announced the start of the first human trial of a new tuberculosis (TB) drug candidate, designated TBA-354. It is the first new TB drug candidate to begin a Phase 1 clinical trial since 2009.

19 Feb 2015

Using NMR to study influenza and TB: an interview with Dr. Tim Cross

In this interview, Tim Cross, Director of the NMR and MRI programs at the National High Magnetic Field Lab (NHMFL) in Tallahassee, Florida, talks about his research into protein structures in viruses and bacteria, and how the findings will affect medical research into disease prevention.

From Bruker BioSpin - NMR, EPR and Imaging 3 Feb 2015

NIAID awards contracts to support early-stage human clinical trials of infectious disease treatments

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded contracts to three organizations to support early-stage human clinical trials of investigational infectious disease treatments. The new awards for the Phase I Clinical Trial Units for Therapeutics increases the number of funded organizations under the program from two to three, expanding capacity for conducting early safety testing of novel investigational drugs.

15 Jan 2015

Scientists discover potential solution to antibiotic resistance

A newly developed technique for screening microbes has led to the discovery of a powerful new antibiotic that can easily kill severe infections in mice, without causing side effects.

8 Jan 2015

Two medical imaging techniques could predict effectiveness of TB drugs

Two medical imaging techniques, called positron emission tomography (PET) and computed tomography (CT), could be used in combination as a biomarker to predict the effectiveness of antibiotic drug regimens being tested to treat tuberculosis (TB) patients, according to researchers at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

5 Dec 2014

Three-day global symposium on Ebola virus, other infectious diseases

The 11th annual International Consortium on Anti-Virals (ICAV) symposium, Infectious Diseases: Global Public-Health Challenges of the Next Decade, will put the challenges posed by several infectious diseases under the microscope, including the Ebola virus, the H7N9 influenza virus, MERS coronavirus and dengue viruses, as well as drug-resistant tuberculosis.

18 Nov 2014

NPS MedicineWise calls all Australians to join the fight against antibiotic resistance

As Antibiotic Awareness Week 2014 is held across Australia from 17-23 November, NPS MedicineWise is asking all Australians to imagine a world without antibiotics and join the fight against antibiotic resistance.

17 Nov 2014

New therapy appears to help tinnitus patients cope better with phantom noise

Patients with tinnitus hear phantom noise and are sometimes so bothered by the perceived ringing in their ears, they have difficulty concentrating. A new therapy does not lessen perception of the noise but appears to help patients cope better with it in their daily lives, according to new research.

31 Oct 2014

Johns Hopkins School of Nursing to launch new HIV curriculum for non-physician providers

The 31-year-old Moore Clinic operated by the Johns Hopkins AIDS Service at the School of Medicine is a historic operation — the second-oldest AIDS clinic in the country. But when Jason Farley, PhD, MPH, CRNP, looks nowadays at the makeup of Moore's caregiving staff, he worries that he's seeing too much history.

31 Jul 2014

CRAG urges researchers to balance goal of shortening treatment for MDR-TB with patient safety

In a viewpoint published this week in The Lancet, the Community Research Advisors Group argue that research into bedaquiline – a new drug, fast tracked for multidrug-resistant tuberculosis (MDR-TB) – should proceed cautiously in people with drug-sensitive tuberculosis.

14 Jul 2014

Viewpoints: Misreading Hobby Lobby; calmer climate for ACA; danger of tuberculosis, measles

Liberals should spend less time lauding the dissents in last week's Hobby Lobby decision by the U.S. Supreme Court and more time reading them.

9 Jul 2014

WHO's annual statistics report shows global life expectancy continues to increase

People everywhere are living longer, according to the "World Health Statistics 2014" published today by WHO. Based on global averages, a girl who was born in 2012 can expect to live to around 73 years, and a boy to the age of 68.

15 May 2014

Otsuka's Deltyba gets EC marketing authorization for MDR-TB treatment

Otsuka Pharmaceutical Co., Ltd. today announced that the European Commission has granted a marketing authorization for Deltyba (delamanid) for use as part of an appropriate combination regimen for pulmonary multidrug-resistant tuberculosis (MDR-TB) in adult patients when an effective treatment regimen cannot otherwise be composed for reasons of resistance or tolerability.

30 Apr 2014

The rising incidence of multi-drug resistant TB: an interview with Dr Myriam Haxaire-Theeuwes, Compound Development Team Leader, Janssen

MDR-TB is on the rise in a number of regions in the world, because progress towards targets for diagnosis and treatment of multidrug-resistant TB (MDR-TB) is far off-track.

29 Apr 2014

TB Alliance advances first-ever TB drug regimen to global Phase 3 clinical trial

Based on positive results from earlier clinical studies, TB Alliance is advancing the first-ever drug regimen designed to treat both drug-sensitive and some forms of multi-drug resistant tuberculosis (TB) to a global Phase 3 clinical trial.

25 Apr 2014

Johnson & Johnson's sales increase 3.5% to $18.1 billion in first quarter 2014

Johnson & Johnson today announced sales of $18.1 billion for the first quarter of 2014, an increase of 3.5% as compared to the first quarter of 2013. Operational results increased 5.3% and the negative impact of currency was 1.8%. Domestic sales increased 2.2%. International sales increased 4.5%, reflecting operational growth of 7.9% and a negative currency impact of 3.4%.

15 Apr 2014

New policy report on multi-drug resistant tuberculosis

Leading politicians, officials, researchers and civil society organisations convened in Brussels at the launch of European Voice’s multi-drug resistant (MDR-TB) policy report in the lead up to World TB day, to discuss the rising incidence of MDR-TB, the need for more effective treatments, new vaccines and better diagnostics and what needs to done at a European level to tackle this preventable disease.

28 Mar 2014

Viewpoints: Be careful what you pray for; health law 'freakouts;' concerns about imported drugs

On Tuesday, the Supreme Court will consider a proposition that will strike many Americans as bizarre: that large, for-profit businesses can refuse on religious grounds to comply with a federal mandate that they include contraception in their employee health plans (3/25).

26 Mar 2014

Tuberculosis control needs a complete and patient-centric solution

Whether it is mobile phone service or vacation travel, good businesses know that success depends on providing a complete and customer-centric solution. Should patients with tuberculosis not be offered a complete solution that is patient-centered? After all, millions are affected and a large market at the base-of-the-pyramid (BoP) remains unserved.

24 Mar 2014

New consensus statements developed to help tackle drug-resistant TB

New consensus statements have been developed to help tackle the growing threat of multidrug-resistant tuberculosis (TB) and extensively drug-resistant tuberculosis (TB).