Ductal Carcinoma in Situ (DCIS) News and Research

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Ductal Carcinoma in Situ (DCIS) is a condition where the cells lining the milk ducts (the channels in the breast that carry milk to the nipple) are cancerous, but stay contained within the ducts without growing through into the surrounding breast tissue. DCIS may affect just one area of the breast, but can be more widespread and affect different areas at the same time. Sometimes DCIS may be described as pre-cancerous, pre-invasive, non-invasive, or intraductal cancer.

Lumpectomy plus radiation associated with reduced risk of breast cancer death, study finds

Lumpectomy plus radiation was associated with a small clinical benefit in reduced risk of breast cancer death compared with lumpectomy or mastectomy alone in women with ductal carcinoma in situ, a noninvasive early form of breast cancer.

13 Aug 2018

Removing the cancer label - overhaul in cancer classification proposed

Australian researchers have asked for changes in the way doctors tend to label low risk cancerous conditions as “cancer” leading to over treatment. Certain diagnoses such as localised prostate cancer or “stage 0” breast cancers need to be looked at say the researchers at the University of Sydney and Bond University to prevent aggressive treatment where it is not needed.

12 Aug 2018

Study provides insight into how early-stage breast cancer progresses to invasive ductal carcinoma

A new genetic-based model may explain how a common form of early-stage breast cancer known as ductal carcinoma in situ progresses to a more invasive form of cancer say researchers at The University of Texas MD Anderson Cancer Center.

4 Jan 2018

Surveillance rather than surgery can be safe option for women with FEA lesions

The detection of certain non-cancerous "high risk" breast lesions can lead to surgical treatment in women, but one of the largest studies of a specific type of high-risk lesion, flat epithelial atypia (FEA), calls for close observation, rather than surgical removal of these lesions in most cases, according to study results published on the web site of the Journal of the American College of Surgeons in advance of print.

31 Oct 2017

Updated guidelines offer support for appropriate, safe use of accelerated partial-breast irradiation

Cleveland Clinic researcher Chirag Shah, M.D., led the development of updated guidelines for the appropriate and safe utilization of accelerated partial-breast irradiation. The guidelines are published online in the journal, Brachytherapy.

26 Oct 2017

Study: Major databases provide varying estimates of racial gaps in IBR after mastectomy

Three major national databases include varying estimates of racial gaps in the use of immediate breast reconstruction (IBR) after mastectomy for breast cancer, reports a study in the March issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

30 Mar 2017

DCIS patients more likely to be alive ten years later than women in general population

Women over 50 who have been treated for ductal carcinoma in situ (DCIS) are more likely to be alive ten years later than women in the general population, according to new research presented at the European Cancer Congress 2017.

27 Jan 2017

HER2-targeted dendritic cell vaccine shows promise for treating early-stage breast cancer patients

Deregulation and inhibition of the immune system contributes to cancer development. Many therapeutic strategies aim to restimulate the immune system to recognize cancer cells and target them for destruction.

3 Jan 2017

Radiation boost provides added benefit to DCIS patients following breast-conserving surgery and WBRT

A supplemental "boost" of radiation improves local control and provides an incremental benefit in decreasing breast cancer recurrence for patients with Ductal Carcinoma In Situ (DCIS) who receive whole breast radiation therapy radiation (WBRT) following lumpectomy, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

27 Sep 2016

ASTRO honors Ms. Keresztes with 2016 Survivor Circle Award

The American Society for Radiation Oncology has chosen Theresa A. Keresztes, a resident of Wellesley, Massachusetts, to receive the 2016 Survivor Circle Award.

20 Jul 2016

Delay in radiation therapy increases chances of DCIS recurrence in women

Delaying radiation therapy too long after surgery significantly increases the risk of recurrent tumors in women treated for very early, or what is referred to as "stage 0," breast cancer, according to new research at Washington University School of Medicine in St. Louis.

19 Apr 2016

New USPSTF breast cancer screening recommendations may result in lethal consequences for women

If followed, new U.S. Preventive Services Task Force breast cancer screening recommendations will result in thousands of unnecessary deaths each year and thousands more women enduring extensive and expensive treatment than if their cancer had been found early by an annual mammogram.

12 Jan 2016

Anastrozole drug effective in treating early form of breast cancer

The drug anastrozole is effective in treating an early form of breast cancer, according to a clinical trial led by Queen Mary University of London. The results of the IBIS-II DCIS trial show that anastrozole is as effective as tamoxifen for this type of breast cancer and could offer a new treatment option for post-menopausal women.

12 Dec 2015

APBI brachytherapy improves overall survival in selected patients with early stage breast cancer

The Groupe Européen de Curiethérapie European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) today announced results from a prospective, randomized, multicenter phase III study comparing accelerated partial breast irradiation (APBI) with interstitial multicatheter brachytherapy to whole breast irradiation (WBI).

20 Oct 2015

Study raises new questions about the best way to treat early cancer cells that define DCIS

Treatment patterns for ductal carcinoma in situ (DCIS) have shifted since the 1990s, with more U.S. women opting for lumpectomy in combination with radiation rather than single-breast mastectomy, according to a study lead by Duke Cancer Institute researchers.

12 Oct 2015

Scientists awarded £417,000 to develop a gel to advance breast cancer research, reduce animal testing

Scientists at the Universities of Manchester and Nottingham have been funded to develop a gel that will match many of the biological structures of human breast tissue, to advance cancer research and reduce animal testing.

7 Oct 2015

Women diagnosed with ductal carcinoma in situ more likely to die from breast cancer

Women diagnosed with ductal carcinoma in situ (DCIS) are twice as likely to die from breast cancer compared to the general U.S. population, according to a new study led by Dr. Steven Narod.

21 Aug 2015

Researcher study potential biomarker to determine patients at risk for aggressive breast cancer

Biomarkers are an important part in detecting certain cancers such as the BRCA gene in breast cancer and the PSA antigen in prostate cancer. They are easy to identify in a blood test and can help in diagnosing and giving a prognosis.

12 Aug 2015

Breast surgery for low-grade ductal carcinoma in-situ may not change patients' survival rate

In a study published in JAMA Surgery on June 3, researchers from Brigham and Women's Hospital report that breast surgery performed at or shortly after a diagnosis of low-grade ductal carcinoma in-situ (DCIS) did not significantly change patients' survival rate.

4 Jun 2015

Scientists identify way to potentially predict progression in patients with early form of breast cancer

Scientists in Manchester have identified a way to potentially predict which patients with an early form of breast cancer will experience disease progression.

16 Apr 2015