Dysentery News and Research

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Clinical study supports the long-lasting impacts of typhoid conjugate vaccine

A single dose of the typhoid conjugate vaccine, Typbar TCV, provides lasting efficacy in preventing typhoid fever in children ages 9 months to 12 years old, according to a new study conducted by researchers at University of Maryland School of Medicine's (UMSOM) Center for Vaccine Development and Global Health (CVD) and led by in-country partners at the Malawi-Liverpool Wellcome Trust (MLW) Clinical Research Programme.

25 Jan 2024

International trade of colistin in animal feed continues unabated

Researchers investigate Enterobacterales species resistance to colistin in Pakistan.

22 Mar 2023

Researchers review bacteriophage treatment

Researchers presented an overview of bacteriophage treatment, including mechanisms, types, design and applications of bacteriophage therapy.

10 Jan 2023

Study demonstrates safety and efficacy of a three-dose whole-parasite vaccine against malaria

A three-dose regimen of a whole-parasite vaccine against malaria – called Plasmodium falciparum sporozoite (PfSPZ) vaccine – demonstrated safety and efficacy when tested in adults living in Burkina Faso, West Africa, which has endemic malaria.

4 Jan 2023

Study casts light on how to combine antibiotics and phage therapy to fight bacterial infection

New research has moved a step closer to harnessing viruses to fight bacterial infection, reducing the threat of antibiotic resistance.

20 Dec 2021

Study offers insights into how Shigella delivers bacterial proteins into our cells

Shigella, a bacterial pathogen that causes dysentery and is the leading cause of childhood diarrheal diseases, inserts a pore called a translocon into an infected person's intestinal cells and then injects bacterial proteins into the cells.

24 Nov 2021

Naturally occurring phage A1-1 kills dysentery-causing bacteria in sub-Saharan Africa, southern Asia

Phages are viruses that infect bacteria and can also be used to treat human infections. However, as with antibiotics, bacteria can readily evolve resistance to phage attack, highlighting a key limitation to the use of phages as therapeutics.

21 Nov 2021

Scientists move a step closer to harnessing viruses to fight antibiotic resistance

As antibiotics increasingly develop resistance to bacteria that cause infection, scientists have moved a step closer to harnessing viruses as an alternative form of therapy.

12 Oct 2021

Pandemic of antibiotic resistance is shortening the lives of children in Bangladesh

Resistance to antibiotics is common and often deadly among children with pneumonia in Bangladesh, according to a new study coauthored by researchers from Massachusetts General Hospital (MGH) with colleagues at the International Centre for Diarrhoeal Disease Research, Bangladesh (abbreviated as icddr,b).

15 Jul 2021

Molecule produced by the immune system can reduce potency of antibiotics

Research from the University of Kent's School of Biosciences has revealed that a molecule produced by the human immune system can severely diminish the potency of certain antibiotics.

18 Mar 2021

Deaths of Chinese children, adolescents from infectious diseases prior to COVID-19 found to be rare

Deaths of children and adolescents in China due to infectious diseases were becoming rare prior to the COVID-19 pandemic, according to a new study.

3 Apr 2020

Research sheds new light on the phage therapy history

In the current situation when the fear of virus infections in the public is common, it is good to remember that some viruses can be extremely beneficial for mankind, even save lives. Such viruses, phages, infect bacteria.

27 Mar 2020

Study suggests average body temperature in humans falling

For decades, people have considered the average human body temperature to be 98.6 F, or 37 degrees Celsius. However, a new study published January 7, 2020, in the journal eLifeindicates this may no longer be the norm – and the researchers suggest a reason for their observed drop in average temperature.

13 Jan 2020

UMSOM research shows even milder cases of diarrheal diseases can lead to child mortality

Diarrheal diseases are a leading cause of death for young children, accounting for nine percent of all deaths worldwide in children under five years of age, with most occurring in children under two years of age.

9 Jan 2020

Antibiotic-resistant shigella strain cases soar in Australia

A drug-resistant strain of a highly contagious sexually-transmitted bowel infection spreads in Victoria, Australia, with a vast majority of cases happening in men who have sex with men.

19 Dec 2019

UMSOM researchers to test the safety, tolerability of prototype Shigella-ETEC vaccine

Each year, millions of people contract serious diarrheal illnesses typically from contaminated food and water. Among the biggest causes of diarrheal diseases are the bacteria Shigella and enterotoxigenic Escherichia coli, and researchers at the University of Maryland School of Medicine are testing a vaccine designed to offer protection against these serious pathogens.

10 Dec 2019

New report highlights the plight of sanitation workers in the developing world

Millions of sanitation workers in the developing world are forced to work in conditions that endanger their health and lives, and violate their dignity and human rights, according to a report released today.

14 Nov 2019

UMSOM receives landmark contract from NIAID for influenza research

Kathleen Neuzil, MD, MPH, Professor of Medicine and Pediatrics and Director of the Center for Vaccine Development and Global Health at the University of Maryland School of Medicine and Dean E. Albert Reece, MD, PhD, MBA, announced that CVD has been awarded a contract from the National Institute of Allergy and Infectious Diseases, with total funding up to more than $200 million over seven years if all contract options are exercised.

20 Sep 2019

UIC researchers receive $1.7 million NCI grant to study Southeast Asian fruit

For generations, traditional healers in Southeast Asia have used the mangosteen fruit to treat skin infections, wounds, dysentery and urinary tract infections.

18 Jan 2019

Drug used to treat amoebic dysentery may block journey of rabies virus in nerves

To successfully infect its host, the rabies virus must move from the nerve ending to the nerve cell body where it can replicate.

24 Aug 2018