Electron Microscopy News and Research

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Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Researchers identified a human monoclonal antibody (mAb), 87G7, with in vitro neutralizing activity against several SARS-CoV-2 VOCs, including Alpha, Beta, Gamma, Delta, and Omicron.

28 Apr 2022

New discovery about nature’s ‘high-end machinery’ could have big implications for biology

Working with tiny bacteria, Michigan State University researchers led by Lee Kroos have made a discovery that could have big implications for biology.

26 Apr 2022

Free fatty acid-binding pocket found to be preserved across spike proteins of beta coronaviruses

Researchers assessed the binding pocket of linoleic acid, an essential free-fatty acid in the receptor-binding domains of the spike protein of beta-coronaviruses.

26 Apr 2022

The response of four SARS-CoV-2 spike variants to linoleic acid removal

A recent paper depicted the differential allosteric response of the SARS-CoV-2 spike variants to linoleic acid.

26 Apr 2022

Quantum dot biomimetic for SARS-CoV-2 examines neurovascular dysregulation related to brain inflammation

Researchers developed SARS-CoV-2 virus-like nanoparticles with a quantum dots core.

26 Apr 2022

Antibodies that neutralize most sarbecoviruses, including SARS-CoV-2 variants

Researchers isolate three mAbs that broadly neutralized sarbecoviruses and carried out virological and structural studies of these mAbs.

21 Apr 2022

New research takes a close look at the most prevalent neurotransmitter in the brain

One of the most important molecules in the brain doesn't work quite the way scientists thought it did, according to new work by researchers at Columbia University Vagelos College of Physicians and Surgeons and Carnegie Mellon University.

21 Apr 2022

CryoEM reveals never-before-seen details of the human androgen receptor

Scientists at Memorial Sloan Kettering Cancer Center (MSK) have glimpsed never-before-seen details of the human androgen receptor -; the protein inside of cells that responds to male-typical hormones like testosterone.

20 Apr 2022

Leica Microsystems wins distinctive Red Dot design award

Leica Microsystems, a leading provider of microscopy and scientific instruments, has won a 2022 Red Dot Award for its digital inspection microscope, Emspira 3.

From Leica Microsystems GmbH 20 Apr 2022

Little-known protein found to play a role in common neurodegenerative disorder

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

20 Apr 2022

Silica exposure drives the rising rates of pneumoconiosis in coal workers

Silica exposure is a driving force behind rising rates of coal workers' pneumoconiosis, according to a new study published by occupational health experts at the University of Illinois Chicago and their collaborators.

12 Apr 2022

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

A recent study illustrated the enhanced distinct clustering of pseudotyped particles (PPs) expressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

12 Apr 2022

Inflammation weakens odor signals and may be responsible for COVID19 loss of smell

Anosmia, the loss of smell, is a frequent and often long-term symptom associated with COVID-19 that can severely burden a person's quality of life, making it extremely difficult to taste foods, detect airborne hazards in the environment and carry out other functions dependent on the sense.

11 Apr 2022

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Researchers used cryogenic electron microscopy (cryo-EM) to determine the structure of the spike (S) protein of BA.2 sub-variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) and compared them with previously determined S structures of Omicron's BA.1 sub-variant.

11 Apr 2022

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

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11 Apr 2022

Advanced microscopy reveals exciting insights into dynamic ultrastructure of the heart

What happens below the cellular level when the heart contracts and relaxes has long been unexplored. Thanks to new ultra-high-resolution electron microscopy techniques, scientists can now watch the heart beating – almost at a molecular level.

8 Apr 2022

Researchers reveal why people with allergic asthma are protected from severe COVID

The vast majority of people infected with the omicron variant of SARS-CoV-2 experience mild cold-like symptoms, moderate flu-like symptoms, or no symptoms at all, but the virus is so transmissible that it still spread deep into lung tissue to cause severe disease and death in thousands of people in the United States in 2022 alone.

7 Apr 2022

Electron Microscopy News and Research

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

New discovery about nature’s ‘high-end machinery’ could have big implications for biology

Free fatty acid-binding pocket found to be preserved across spike proteins of beta coronaviruses

The response of four SARS-CoV-2 spike variants to linoleic acid removal

Quantum dot biomimetic for SARS-CoV-2 examines neurovascular dysregulation related to brain inflammation

Antibodies that neutralize most sarbecoviruses, including SARS-CoV-2 variants

New research takes a close look at the most prevalent neurotransmitter in the brain

CryoEM reveals never-before-seen details of the human androgen receptor

Leica Microsystems wins distinctive Red Dot design award

Little-known protein found to play a role in common neurodegenerative disorder

Silica exposure drives the rising rates of pneumoconiosis in coal workers

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

Inflammation weakens odor signals and may be responsible for COVID19 loss of smell

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

Advanced microscopy reveals exciting insights into dynamic ultrastructure of the heart

Researchers reveal why people with allergic asthma are protected from severe COVID

Researchers demonstrate how a narrow-spectrum antibiotic selectively targets C. diff

Cryo-EM imaging of a key immune protein reveals previously unrecognized binding site

Self-assembling SARS-CoV-2 spike protein-directed nanoparticle vaccines

Life Science Microscopy eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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