Electron Microscopy News and Research

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Super-resolution imaging of the human coronavirus genome during infection

Using high-throughput confocal super-resolution microscopy, scientists visualize the genomic material of the human coronavirus HCoV-229E.

9 Feb 2022

Researchers discover a new function of anti-HIV-1 antibodies

Teams at the Institut Pasteur, CNRS, Vaccine Research Institute (VRI) and Université de Paris have discovered a new function of anti-HIV-1 antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures.

6 Feb 2022

Wistar researchers takes a promising step in the direction of developing HIV vaccine

Nearly four decades after its discovery, HIV has killed 36.3 million people, with no vaccine in sight. However, a new study by researchers at The Wistar Institute, an international biomedical research leader in cancer, immunology, infectious disease, and vaccine development, takes a promising step in the direction of developing an HIV vaccine.

4 Feb 2022

Researchers elucidate first 3D structure of regulator protein complex

Proteins are indispensable components in living organisms. They are not only "building material" for the body – they also make molecular communication between cells possible, they are needed for nerve impulses to occur, and they control chemical reactions.

2 Feb 2022

Illustrating the structural diversity of SARS-CoV-2 Omicron spike

In a new study, a team of researchers used cryo-electron microscopy to determine the spike (S) structures of the SARS-CoV-2 Omicron variant to understand how the mutations that alter its primary sequence impact S conformation.

1 Feb 2022

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

In a new study, researchers evaluated the neutralizing antibody titers in mice vaccinated with messenger ribonucleic acid (mRNA) encoding SARS-CoV-2 spike (S) protein.

1 Feb 2022

Researchers visualize protein machinery of respiration for the first time

Oxygen and sugar are the basis of life for animals, plants, fungi and many bacteria. The metabolic process called respiration makes it possible to convert food into energy for the cells.

31 Jan 2022

Scientists evaluate zoonotic potential of NeoCoV, a coronavirus related to MERS-CoV

Researchers identify ACE2 as the functional receptor of the two close relatives of MERS-CoV, NeoCoV and PDF-2180-CoV, in bats.

30 Jan 2022

Structural proteomics approaches can help in the treatment of neurodegenerative diseases

Two researchers from Skoltech and McGill University have published a review of the promising research field known as structural proteomics in the influential journal Chemical Reviews.

27 Jan 2022

Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

A study recently identified Neurolipin-1 or NRP1, a host factor for SARS-CoV-2 infection, as a cargo retrograde-transported by the ESCPE-1.

26 Jan 2022

Common cystic fibrosis drugs work by directly aiding the protein folding process, study shows

Protein misfolding is a likely culprit in many degenerative disorders. Cystic fibrosis, for instance, is caused by mutations in the CFTR gene that prevent the eponymous protein from assuming its proper configuration.

24 Jan 2022

Constructing SARS-CoV-2 virus-like particles in tobacco plants for vaccine development

In a study published in the latest issue of the Scientific Reports, a team of researchers constructed virus-like particles (VLPs) composed of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M), envelope (E), and nucleocapsid (N) proteins in tobacco plant using Agrobacterium-mediated delivery.

24 Jan 2022

Study shows how SARS-CoV-2 Omicron evades our immune response and remains infective

A recent study published in the journal Science brings a detailed chemical and molecular perspective on the improved evasion of antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the retention of strong interactions with the receptor as two principal factors underneath the notorious transmissibility of the SARS-CoV-2 Omicron variant.

23 Jan 2022

New cryo-EM method may be able to shortcut a big step in modern vaccine development

Scientists at Scripps Research have devised a method that may be able to shortcut one of the big steps in modern vaccine development.

20 Jan 2022

Researchers report isolation of potently neutralizing antibodies against highly transmissible SARS-CoV-2 variants

A recent preprint discusses using a combinatorial phage-display library approach to COVIID-19 antibodies.

18 Jan 2022

Hollow fiber membranes efficiently remove synthetic SARS-CoV-2 from the air

Researchers re-design HFM filters for removing/deactivating viral aerosols.

13 Jan 2022

Study shows that key parts of human immunity are shared in bacteria

The human immune system, that marvel of complexity, subtlety, and sophistication, includes a billion-year-old family of proteins used by bacteria to defend themselves against viruses, scientists at Dana-Farber Cancer Institute and in Israel have discovered.

13 Jan 2022

Exploring the structural basis of antibody evasion and enhanced transmission of the SARS-CoV-2 Omicron variant

In a new study, researchers used cryogenic electron microscopy (cryo-EM) analysis to capture the open and closed states of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant’s spike protein.

13 Jan 2022

Long-term use of blood pressure medication could be contributing to kidney damage

New kidney research from the University of Virginia School of Medicine is raising concerns that long-term use of drugs commonly prescribed to treat high-blood pressure and heart failure could be contributing to kidney damage.

12 Jan 2022

Unique combination of nanomaterials in DNA biosensor enables easier SARS-CoV-2 detection

A recent paper that was published in the Talanta journal dedicated to original reports in pure and applied analytical chemistry presents for the first time the combination of two different nanomaterials – gold nanomaterials (AuNMs) and CDs for the development of an improved electrochemiluminescence (ECL) DNA biosensor.

10 Jan 2022

Electron Microscopy News and Research

Super-resolution imaging of the human coronavirus genome during infection

Researchers discover a new function of anti-HIV-1 antibodies

Wistar researchers takes a promising step in the direction of developing HIV vaccine

Researchers elucidate first 3D structure of regulator protein complex

Illustrating the structural diversity of SARS-CoV-2 Omicron spike

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

Researchers visualize protein machinery of respiration for the first time

Scientists evaluate zoonotic potential of NeoCoV, a coronavirus related to MERS-CoV

Structural proteomics approaches can help in the treatment of neurodegenerative diseases

Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

Common cystic fibrosis drugs work by directly aiding the protein folding process, study shows

Constructing SARS-CoV-2 virus-like particles in tobacco plants for vaccine development

Study shows how SARS-CoV-2 Omicron evades our immune response and remains infective

New cryo-EM method may be able to shortcut a big step in modern vaccine development

Researchers report isolation of potently neutralizing antibodies against highly transmissible SARS-CoV-2 variants

Hollow fiber membranes efficiently remove synthetic SARS-CoV-2 from the air

Study shows that key parts of human immunity are shared in bacteria

Exploring the structural basis of antibody evasion and enhanced transmission of the SARS-CoV-2 Omicron variant

Long-term use of blood pressure medication could be contributing to kidney damage

Unique combination of nanomaterials in DNA biosensor enables easier SARS-CoV-2 detection

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Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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