Electron Microscopy News and Research

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Changes in fibrin clot structure contributes to thrombosis risk in severe COVID-19

Researchers from Europe recently demonstrated altered levels of factor XII (FXII) and its activation products in 2 independent cohorts of critically ill patients with COVID-19 compared to patients suffering from severe acute respiratory distress syndrome caused by the influenza virus (acute respiratory distress syndrome (ARDS)-influenza).

21 Sep 2021

Scientists simulate SARS-CoV-2 virion envelope using Martini 3

A new study proposes an integrative computational approach to model the structure of the SARS-CoV-2 envelope.

20 Sep 2021

Adenovirus-based nanoparticle vaccine elicits potent SARS-CoV-2 neutralizing antibody response

In a study available on the preprint server medRxiv*, researchers have created a vaccine designed to overcome issues associated with attenuated-virus vaccines.

17 Sep 2021

Study provides the most detailed view of how ribosomes are assembled in human cells

All cells need ribosomes to make the proteins necessary for life. These multi-component molecular machines build complex proteins by stitching building blocks together according to instructions encoded in the cell's messenger RNAs.

16 Sep 2021

SARS-CoV-2 variants show substantial differences in spike structure

To investigate the impact of these mutations, researchers performed cryo-electron microscopy analysis on the variants spike proteins to determine any structural changes.

15 Sep 2021

UNSW Sydney scientists discover how tiny anchors help the cells to stay in place

Most of the cells in our bodies – be they bone, muscle or pancreas cells – are locked into the right place with the help of tiny anchors.

15 Sep 2021

Microscopy paired with AI leads to a fast, accurate, and cost-effective COVID-19 test

Beckman researchers paired microscopy with artificial intelligence to develop a COVID-19 test that's fast, accurate, and cost-effective. All we need to do is say "ahh."

12 Sep 2021

Study identifies FDA-approved drugs that are effective in suppressing SARS-CoV-2 replication

Despite the development of SARS-CoV-2 vaccines, effective therapeutics are needed until worldwide immunity has been achieved.

10 Sep 2021

Food science principles help scientists to understand inner workings of cellular compartments

Johns Hopkins Medicine researchers report that food science principles have helped them determine how unusual droplets within cells stay organized and avoid dissolving into the rest of the cell's gelatinous interior.

9 Sep 2021

Breakthrough discovery could pave the way for new non-opioid painkillers to treat neuropathic pain

Monash University researchers have made a breakthrough discovery that could pave the way for the development of novel non-opioid painkillers to safely and effectively treat neuropathic pain.

8 Sep 2021

Neuroscientists visualize ultrastructural changes to dendritic spines during structural plasticity

Researchers at the Max Planck Florida Institute for Neuroscience have developed a new imaging technique capable of visualizing the dynamically changing structure of dendritic spines with unprecedented resolution.

6 Sep 2021

Development of extra protective broad-spectrum antimicrobial face shield

In a new study available on the preprint server Preprints*, researchers have innovated a transparent face shield with intrinsic antimicrobial activity.

30 Aug 2021

Study reveals how SARS-CoV-2 variants of concern modulate receptor and antibody binding

In a trailblazing engineering effort, Canadian and US researchers indicate that the emergence of novel variants of SARS-CoV-2 stems from the mutations of spike glycoprotein that confer either increased affinity for the host cell receptor or increased antibody evasion.

30 Aug 2021

New study maps the evolution of the SARS-CoV-2 delta and delta plus variants

The SARS-CoV-2 delta variant bears the D164G mutation, which is known to enhance viral fitness. However, a number of additional mutations are known to be common to the delta and delta plus lineages, at least 25 as identified in a study recently published in the Journal of Autoimmunity, mainly located on the spike protein of the virus.

30 Aug 2021

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

In the nearly 1 million Americans living with multiple sclerosis, the fatty substance that insulates the nerves of the central nervous system—called myelin—is damaged.

24 Aug 2021

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal neurodegenerative diseases in people and animals-; and how they can be potentially targeted by new therapies.

24 Aug 2021

Study suggests algorithm may help optimize future COVID-19 vaccine design

Scientists predict the COVID-19 pandemic is on its way to becoming endemic. The rising spread of COVID-19 variants such as Delta has helped infect unvaccinated and some vaccinated individuals. COVID-19 vaccines continue to be the best way to protect against severe illness and death, but there may be a need for vaccines to protect against a specific variant.

23 Aug 2021

How do glycans affect SARS-CoV-2 spike protein openings?

In a paper recently uploaded to the bioRxiv* preprint server, the role of glycan coating on the SARS-CoV-2 spike protein is further investigated by molecular dynamics simulations of the glycosylated and non-glycosylated protein, identifying several key glycans that play a role in stabilizing and protecting the RBD, and also encourage bonding with the ACE2 receptor.

18 Aug 2021

Protein implicated in tumor growth may protect against neurodegenerative diseases

Cells translate their genetic material at rapid rates with exquisite precision to reproduce, repair damage or even combat disease.

17 Aug 2021

Making the nanobody big again for Cryo-EM

Researchers describe the method that allows high-resolution structure determination of small proteins by single-particle cryo-EM using a Legobody.

17 Aug 2021

Electron Microscopy News and Research

Changes in fibrin clot structure contributes to thrombosis risk in severe COVID-19

Scientists simulate SARS-CoV-2 virion envelope using Martini 3

Adenovirus-based nanoparticle vaccine elicits potent SARS-CoV-2 neutralizing antibody response

Study provides the most detailed view of how ribosomes are assembled in human cells

SARS-CoV-2 variants show substantial differences in spike structure

UNSW Sydney scientists discover how tiny anchors help the cells to stay in place

Microscopy paired with AI leads to a fast, accurate, and cost-effective COVID-19 test

Study identifies FDA-approved drugs that are effective in suppressing SARS-CoV-2 replication

Food science principles help scientists to understand inner workings of cellular compartments

Breakthrough discovery could pave the way for new non-opioid painkillers to treat neuropathic pain

Neuroscientists visualize ultrastructural changes to dendritic spines during structural plasticity

Development of extra protective broad-spectrum antimicrobial face shield

Study reveals how SARS-CoV-2 variants of concern modulate receptor and antibody binding

New study maps the evolution of the SARS-CoV-2 delta and delta plus variants

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

Study suggests algorithm may help optimize future COVID-19 vaccine design

How do glycans affect SARS-CoV-2 spike protein openings?

Protein implicated in tumor growth may protect against neurodegenerative diseases

Making the nanobody big again for Cryo-EM

Life Science Microscopy eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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