Electron Microscopy News and Research

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New ghost imaging algorithm produces higher-resolution image reconstruction with better contrast

Although electron microscopy can already reveal details as small as one nanometer, ongoing research seeks to break through barriers limiting image quality and reducing the optical dose on the samples. Aberration is a common problem in electron microscopy that can reduce the resolution and quality of the images produced.

3 Mar 2023

Gene mutation capable of regulating pain discovered

Pain afflicts at least 1.5 billion people worldwide, and despite the availability of various painkilling drugs, not all forms of pain are treatable.

3 Mar 2023

Using the origami technique to design RNA nanostructures

Researchers from Aarhus University and Berkeley Laboratory have designed RNA molecules, that folds into nanoscale rectangles, cylinders, and satellites, and have studied their 3D structure and dynamics with advanced nanotechnological methods.

28 Feb 2023

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

A new study in the journal Nature Communications aimed to analyze the aggregation propensity in the proteins of both SARS-CoV-2 and SARS-CoV.

21 Feb 2023

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Researchers reported the circulation of a novel MERS-like coronavirus among Malayan pangolins, Manis javanica HKU4-associated CoV (MjHKU4r-CoV).

21 Feb 2023

HKU research advances understanding of the fundamental biological processes of gene regulation

A research team from the University of Hong Kong led by Professor Xiang David Li from the Department of Chemistry in collaboration with Dr Yuanliang Zhai from the HKU School of Biological Sciences and Dr Jason Wing Hon Wong and Dr Xiucong Bao from the HKU School of Biomedical Sciences recently made a key breakthrough in understanding how genetic information encoded in our DNA is 'read' and why errors in 'reading' such information can often lead to developmental defects or cancers.

20 Feb 2023

Structure of DREADD designer receptor could pave the way for creating next generation tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells.

20 Feb 2023

In-depth assessment of muscle biopsies in patients with long COVID

Researchers analyzed skeletal muscle biopsies of patients with persistent fatigue and malaise post-exertion to determine the underlying mechanisms of long COVID.

20 Feb 2023

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Electrochemical method helps to continuously witness and analyze details of protein folding

Scientists are not yet clear on how the tau protein changes from a benign protein essential for normal function in our brains into the toxic neurofibrillary tangles that are a signature of Alzheimer's and other neurodegenerative diseases.

15 Feb 2023

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Researchers developed spherical hydrogel inhalation for enhanced lung defense to protect against SARS-CoV-2 infections.

13 Feb 2023

Study demonstrates antiviral effects of vinegar against SARS-CoV-2

A study published in the journal PLOS ONE demonstrates the effectiveness of acetic acid, the main component of vinegar, in inactivating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Feb 2023

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

Researchers analyze prophages of the LF82 strain of adherent-invasive Escherichia coli to better understand their behavior in vitro and within macrophages.

8 Feb 2023

Cryo-EM provides new insights into the structure of the centromeric region

The genetic material inside cells is organized into structures called chromosomes. The centromere is essential for the correct division of the chromosomes via interaction with spindle microtubules when cells divide and grow.

6 Feb 2023

New insights into the release of microplastics from breastmilk storage bags

Researchers from China analyzed the quantity, size, and composition of microplastics and other particle matter released into breastmilk from disposable breastmilk storage bags.

6 Feb 2023

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Limb-girdle muscular dystrophy type 3 (LGMD D3) is a rare disease causing progressive muscle weakness, caused by point mutations in the hnRNPDL-2 protein.

3 Feb 2023

Light-activated nanoscale drills can combat infectious fungi

That stubborn athlete's foot infection an estimated 70% of people get at some point in their life could become much easier to get rid of thanks to nanoscale drills activated by visible light.

1 Feb 2023

Structure and function of the first FDA-approved treatment for Ebola virus discovered

Scientists at La Jolla Institute for Immunology (LJI) have uncovered the structure and function of the first FDA-approved treatment for Zaire ebolavirus (Ebola virus).

30 Jan 2023

Study shows improved host health by modulating intestinal microbiota

Researchers presented intestinal microbiota modulation as a probable therapeutic option for diseases such as Crohn’s disease (CD).

26 Jan 2023

Cryo-electron microscopy reveals detailed blueprint of viral genome replication machinery

RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell.

25 Jan 2023

Electron Microscopy News and Research

New ghost imaging algorithm produces higher-resolution image reconstruction with better contrast

Gene mutation capable of regulating pain discovered

Using the origami technique to design RNA nanostructures

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

HKU research advances understanding of the fundamental biological processes of gene regulation

Structure of DREADD designer receptor could pave the way for creating next generation tools

In-depth assessment of muscle biopsies in patients with long COVID

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Electrochemical method helps to continuously witness and analyze details of protein folding

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Study demonstrates antiviral effects of vinegar against SARS-CoV-2

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

Cryo-EM provides new insights into the structure of the centromeric region

New insights into the release of microplastics from breastmilk storage bags

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Light-activated nanoscale drills can combat infectious fungi

Structure and function of the first FDA-approved treatment for Ebola virus discovered

Study shows improved host health by modulating intestinal microbiota

Cryo-electron microscopy reveals detailed blueprint of viral genome replication machinery

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