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Precision control of DNA separation using an electric field

An electric voltage can be used to propel DNA molecules through a channel a few nanometers deep, or to stop them in their tracks. In a strong electric field the molecules judder along the channel, while in weaker fields they move more smoothly. This enables DNA fragments to be 'captured' on a chip and separated for analysis.

24 Jun 2008

New insight into radiation damage to DNA

A new technique for assessing the damage radiation causes to DNA indicates that the spatial arrangement of damaged sites, or lesions, is more important than the number of lesions in determining the severity of the damage.

24 Mar 2008

Protein fingerprinting made easy

Combining some traditional experimental methods of molecular biology with computational methods of artificial intelligence, a group of researchers from Ruder Boskovic Instititute and Faculty of Natural Sciences and Mathematics from Zagreb, Croatia, demonstrated a novel approach for producing 'protein fingerprints' of diverse tissues.

13 Dec 2007

SEBIA joins EDMA corporate membership

EDMA , the European Diagnostic Manufacturers Association welcomes SEBIA as new corporate affiliate, bringing the Association's overall membership up to 33 major IVD companies and 21 National Associations.

12 Dec 2007

Fast way of spotting multidrug resistant bacteria could help stop outbreaks in hospitals

A type of bacterium widely found on our skin and in the environment has now become a major threat in hospitals where it can cause serious infections, such as pneumonia in severely ill patients.

27 Nov 2007

There is a new twist on the question of how biological clocks work

In recent years, scientists have discovered that biological clocks help organize a dizzying array of biochemical processes in the body. Despite a number of hypotheses, exactly how the microscopic pacemakers in every cell in the body exert such a widespread influence has remained a mystery.

21 Nov 2007

Proteins found that could be used to improve diagnosis of hepatocellular carcinoma

Researchers report in the October 2007 issue of Molecular & Cellular Proteomics that they have identified proteins that could be used to improve the diagnosis of hepatocellular carcinoma, the most common type of liver cancer.

8 Oct 2007

New test detects the presence of biogenic amines

Researchers in California are reporting development of a fast, inexpensive test suitable for home use that could help millions of people avoid those 'out of the blue' headaches that may follow consumption of certain red wines, cheese, chocolate, and other aged or fermented foods.

2 Oct 2007

Discovery of two new proteins associated with colorectal cancer

Researchers at the Zhejiang University, Hangzhou have discovered that mimecan and Thioredoxin Domain-Containing Protein 5 (TXNDC5) were differentially expressed in colorectal adenoma.

25 Sep 2007

Alternative methods proposed to detect pesticides and antibiotics in water and natural food

Water or food of natural origins (from plants or animals) that we consume on a daily basis can contain unwanted ‘supplies' for our organism, such as pesticides or antibiotics.

18 Sep 2007

Mechanistic model of DNA repair

Ionizing radiation, toxic chemicals, and other agents continually damage the body's DNA, threatening life and health: unrepaired DNA can lead to mutations, which in turn can lead to diseases like cancer.

6 Aug 2007

Jefferson scientist shares patent for DNA analysis

A basic scientist in the Department of Surgery at Jefferson Medical College and the Kimmel Cancer Center at Jefferson has shared a patent on what may someday be a ubiquitous tool in DNA analysis.

19 Jul 2007

Snake venom medication

A chemist at the Vienna University of Technology (TU Vienna) is looking for unusual structures in snake venom and plans to prove their medical effectiveness.

16 Jun 2007

Salmonella outbreak tails off but 628 infected by contaminated peanut butter

Latest figures from the U.S. Centers for Disease Control and Prevention (CDC), say since 1st August 2006, 628 people in 47 states have been infected with salmonellosis after eating peanut butter contaminated with the Tennessee strain of Salmonella.

4 Jun 2007

Radically different approach to nuclear magnetic resonance

Detecting the molecular structure of a tiny protein using nuclear magnetic resonance (NMR) currently requires two things: a million-dollar machine the size of a massive SUV, and a large sample of the protein under study.

16 May 2007

Nanoparticles could damage DNA and lead to cancer

Tissue studies indicate that nanoparticles, engineered materials about a billionth of a meter in size, could damage DNA and lead to cancer, according to research presented at the 2007 Annual Meeting of the American Association for Cancer Research.

18 Apr 2007

Handheld instrument assesses dental disease in minutes

Who would have guessed that when the Star Trek medical diagnostic tool known as the tricorder makes its appearance in real life, the first user might be . . . your dentist.

5 Apr 2007

A fully integrated microfluidic genetic analysis system with sample-in-answer-out capability

In an accomplishment that represents a significant step toward an era of rapid, inexpensive, bedside testing for cancer, researchers at the University of Virginia have developed a microfluidic device that can process human blood samples and yield diagnostic results within an hour.

8 Jan 2007

Templated self-assembly of quantum dots from aqueous solution using protein scaffolds

Quantum dots are rapidly becoming biomedical researchers' tool of choice for adding a fluorescent label to a wide variety of biomolecules.

20 Nov 2006

Scientists identify novel central nervous system proteins affected by chronic alcohol exposure

Researchers at the University at Buffalo studying the effects of alcohol on the brain, using zebrafish as a model, have identified several novel central nervous system proteins that are affected by chronic alcohol exposure.

31 Aug 2006