Electrophysiology News and Research

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Metrion Biosciences expands ion channel drug discovery service capabilities and in-house expertise

Metrion today announced it has expanded its capabilities and expertise through the addition of automated low volume liquid handling capability.

From Metrion Biosciences Limited 7 Dec 2021

First pediatric-only guidelines for the use of pacemakers and implantable defibrillators

Children's Hospital Los Angeles cardiologist Michael Silka, MD, helped to pioneer the development of indications for the use of pacemakers and implantable defibrillators in young patients.

6 Dec 2021

Study reports first-ever modeling of the electrical activity of circadian clock neurons in diurnal species

It's no secret that jet lag and night-shift work can wreak havoc on the way our body's internal clock syncs up our daily wake-sleep cycle, known as circadian rhythm, but now researchers say they are a step closer to understanding how the brain creates behavioral rhythms optimized for diurnal, rather than nocturnal, life.

30 Nov 2021

Many long-haul COVID-19 patients may experience breathing issues, chronic fatigue syndrome

Many long-haul COVID-19 patients have chronic fatigue syndrome and other breathing issues months after their initial COVID-19 diagnosis, according to study in JACC: Heart Failure, which is the first of its kind to identify a correlation between long-haul COVID-19 and chronic fatigue syndrome.

29 Nov 2021

Clinical drug research for the treatment of CNS and neurological disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

29 Nov 2021

Persistent opioid use among 12% of patients after cardiac implantable electronic device procedures

About 12 percent of patients who receive implantable cardiac devices such as a pacemaker or defibrillator and fill an opioid prescription after surgery will consistently use the pain medication in the months afterward, raising the potential for addiction following these common procedures and identifying another pathway that could contribute to the national opioid crisis, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

26 Nov 2021

Researchers develop AI-based method for identifying patients at risk of atrial fibrillation

Atrial fibrillation-;an irregular and often rapid heart rate-;is a common condition that often leads to the formation of clots in the heart that can travel to the brain to cause a stroke.

15 Nov 2021

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Researchers at the University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that a new compound they created reduces the sensation of pain by regulating a biological channel linked to pain.

10 Nov 2021

Single mathematical equation can be used to predict a life-threatening heart rhythm

How ventricular fibrillation will behave in an individual patient can be accurately modelled and predicted using a single mathematical equation, according to Flinders University researchers.

9 Nov 2021

Substance use, high alcohol consumption may increase the risk of new-onset atrial fibrillation

Using methamphetamines, opiates, cocaine and cannabis, as well as acute alcohol consumption (alcohol consumption within a week preceding an atrial fibrillation event) may increase the risk of new-onset atrial fibrillation, according to preliminary research to be presented at the American Heart Association's Scientific Sessions 2021.

8 Nov 2021

Some immune checkpoint inhibitors can cause serious arrhythmias and myocarditis

Immune checkpoint inhibitors (ICIs) have transformed cancer care by unleashing T-cells to fight tumors, but they can cause serious cardiotoxicities including myocarditis. ICI-induced myocarditis represents a new clinical syndrome because of the novelty and considerable usage of ICIs.

7 Nov 2021

Neural synchrony found to be predictive for favorable outcome after coma

Coma patients in ICU, e.g. after cardiac arrest, have been targeted in research projects for many years. One of the key questions is how to predict the outcome after coma. Current approaches are often based on qualitative assessment of electroencephalogram (EEG) patterns.

6 Nov 2021

Socioeconomic barriers impact women's cardiovascular health early in life

Socioeconomic barriers unique to women, including inadequate access to contraception, postpartum follow-up and maternity leave, set women's cardiovascular health back early in life and can result in heart attack, stroke and cardiovascular death in at-risk populations later in life, according to a review paper from the American College of Cardiology Cardiovascular Disease in Women Committee and Health Equity Taskforce published in the Journal of the American College of Cardiology.

1 Nov 2021

Using deep brain stimulation to treat Parkinson’s Disease

News-Medical spoke to Dr. Aryn Gittis about her latest research into Parkinson's disease and how deep brain stimulation could be used to help treat it.

27 Oct 2021

DOD funds first human trial of a device to enhance the natural brain cleansing system

The U.S. Department of Defense is funding the first human trial of a device to speed up and enhance the natural system of brain cleansing that occurs when we sleep.

26 Oct 2021

Racial and ethnic minority cardiologists face discrimination, analysis reveals

Underrepresented racial and ethnic minorities in the cardiovascular workforce continue to experience a lack of representation and face discrimination, inequitable job negotiations and burnout in their professional lives, according to an analysis of the 2015 Professional Life Survey conducted by the American College of Cardiology. The analysis published today in the Journal of the American College of Cardiology.

19 Oct 2021

Patient-specific whole-heart computational models provide insights for personalized treatment

Whole-heart ventricular modeling has come a long way in recent years and is currently witnessing the evolution of a variety of computational approaches, especially within the realm of personalized technologies for patient-specific clinical applications.

29 Sep 2021